Difference between revisions of "Team:SSTi-SZGD"

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<head>
 
<head>
 
<link rel="stylesheet" type="text/css" href="https://2018.igem.org/Team:SSTi-SZGD/css/Home?action=raw&ctype=text/css">
 
<link rel="stylesheet" type="text/css" href="https://2018.igem.org/Team:SSTi-SZGD/css/Home?action=raw&ctype=text/css">
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<link rel="stylesheet" type="text/css" href="https://2018.igem.org/Team:SSTi-SZGD/css/Footer?action=raw&ctype=text/css">
 
<script src="https://2018.igem.org/Team:SSTi-SZGD/js/Home?action=raw&ctype=text/javascript" type="text/javascript" charset="utf-8"></script>
 
<script src="https://2018.igem.org/Team:SSTi-SZGD/js/Home?action=raw&ctype=text/javascript" type="text/javascript" charset="utf-8"></script>
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<script src="https://2018.igem.org/Team:SSTi-SZGD/js/Footer?action=raw&ctype=text/javascript" type="text/javascript" charset="utf-8"></script>
 
</head>
 
</head>
  
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<!--page_content-->
 
<!--page_content-->
<div class="page_content">
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<div class="page_content container">
 
 
<!--slogan-->
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<div class="col-xs-12 col-sm-10 name hidden-xs">Team:SSTi-SZGD</div>
<section class="container-fluid slogan">
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<div class="col-xs-12 col-sm-10 name visible-xs">SSTi-SZGD</div>
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<!--ProjectVideo-->
<div class="slogan_mask">
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<section class="col-xs-12 col-sm-10 ProjectVideo">
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<video width="100%" controls="controls">
<div class="Hyaluronic">
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<source src="https://static.igem.org/mediawiki/2018/9/90/T--SSTi-SZGD--ProjectVideo.mp4" type="video/mp4" />
Hyaluronic acid micro factory : A bacterium produces low molecular weight hyaluronic acid
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<source src="movie.ogg" type="video/ogg" />
<!--{cn}透明质酸微工厂:一菌直接生产小分子透明质酸-->
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<source src="https://static.igem.org/mediawiki/2018/9/9c/T--SSTi-SZGD--ProjectVideo.webm" type="video/webm" />
</div>
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<object data="https://static.igem.org/mediawiki/2018/9/90/T--SSTi-SZGD--ProjectVideo.mp4" width="100%">
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<embed src="movie.swf" width="100%" />
<div class="used">
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</object>
Engineering strain : Bacillus subtilis
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</video>
<!--{cn}工程菌株:枯草芽孢杆菌-->
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</div>
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<div class="origin">
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Genetic origin : Streptococcus equi and Leech
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<!--{cn}遗传起源:马链球菌和水蛭-->
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</div>
+
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<div class="href_slogan">
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<a href="#description">
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read more
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<!--{cn}阅读更多-->
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</a>
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</div>
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+
</div>
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+
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</section>
 
</section>
 
 
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In our modern world, millions of people do not hesitate to spend a fortune to achieve younger looking and vibrant appearances, thus the cosmetic industry keeps growing.
 
In our modern world, millions of people do not hesitate to spend a fortune to achieve younger looking and vibrant appearances, thus the cosmetic industry keeps growing.
 
<!--{cn}在我们的现代社会,数以百万计的人会不假思索地花一大笔钱,以获得更年轻和更加充满活力的外观,因此化妆品行业不断增长。-->
 
<!--{cn}在我们的现代社会,数以百万计的人会不假思索地花一大笔钱,以获得更年轻和更加充满活力的外观,因此化妆品行业不断增长。-->
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<span class="before"></span>
 +
<span class="after"></span>
 
</div>
 
</div>
 
<div class="col-xs-12 col-md-6 img"></div>
 
<div class="col-xs-12 col-md-6 img"></div>
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<div class="col-xs-12 break">
 
<div class="col-xs-12 break">
<img src="img/home_break.png"/>
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<img src="https://static.igem.org/mediawiki/2018/thumb/4/41/T--SSTi-SZGD--home_break.png/187px-T--SSTi-SZGD--home_break.png"/>
 
</div>
 
</div>
 
 
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Hyaluronic acid is one of the mostly used ingredients in cosmetic products, thanks to its exceptional water retention ability that helps rejuvenating skin and reducing wrinkles.  
 
Hyaluronic acid is one of the mostly used ingredients in cosmetic products, thanks to its exceptional water retention ability that helps rejuvenating skin and reducing wrinkles.  
 
<!--{cn}透明质酸是化妆品中最常用的成分之一,因为它具有超强的保水能力,可以帮助皮肤恢复活力,减少皱纹。-->
 
<!--{cn}透明质酸是化妆品中最常用的成分之一,因为它具有超强的保水能力,可以帮助皮肤恢复活力,减少皱纹。-->
 +
<span class="before"></span>
 +
<span class="after"></span>
 
</div>
 
</div>
 
<div class="clearfix"></div>
 
<div class="clearfix"></div>
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<div class="col-xs-12 break original">
 
<div class="col-xs-12 break original">
<img src="img/home_break.png"/>
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<img src="https://static.igem.org/mediawiki/2018/thumb/4/41/T--SSTi-SZGD--home_break.png/187px-T--SSTi-SZGD--home_break.png"/>
 
</div>
 
</div>
 
 
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Hyaulornic acid production via microbial fermentation is generally through  
 
Hyaulornic acid production via microbial fermentation is generally through  
 
<!--{cn}通过微生物发酵产生的下透明质酸通常是通过-->  
 
<!--{cn}通过微生物发酵产生的下透明质酸通常是通过-->  
<i>Streptococus species<!--{cn}兽疫链球菌--></i>
+
<i>Streptococus<!--{cn}兽疫链球菌--></i>
, which contains endotoxins. We constructed recombinant Bacillus subtilis, the food-grade safe species, to mass produce hyaluronic acid.
+
species, which contains endotoxins. We constructed recombinant  
<!--{cn},但其中含有内毒素。为了安全的大量生产透明质酸,我们构建了食品级安全菌枯草芽孢杆菌。-->
+
<!--{cn},但其中含有内毒素。为了安全的大量生产透明质酸,我们构建了食品级安全菌-->
 +
<i>Bacillus subtilis<!--{cn}枯草芽孢杆菌--></i>
 +
, the food-grade safe species, to mass produce hyaluronic acid.
 +
<!--{cn}-->
 +
<span class="before"></span>
 +
<span class="after"></span>
 
</div>
 
</div>
 
<div class="col-xs-12 col-md-6 img"></div>
 
<div class="col-xs-12 col-md-6 img"></div>
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<div class="col-xs-12 break">
 
<div class="col-xs-12 break">
<img src="img/home_break.png"/>
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<img src="https://static.igem.org/mediawiki/2018/thumb/4/41/T--SSTi-SZGD--home_break.png/187px-T--SSTi-SZGD--home_break.png"/>
 
</div>
 
</div>
 
 
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<div class="col-xs-12 col-md-6 img"></div>
 
<div class="col-xs-12 col-md-6 img"></div>
 
<div class="col-xs-12 col-md-6 content">
 
<div class="col-xs-12 col-md-6 content">
After covalently cross-link, low molecular weight hyaluronic acid (LMW-HA) forms stable hydrogel that is important for film-forming process. By introducing a hydrolase gene, we constructed a B. Subtilis strain that is able to biosynthesize LMW-HA.
+
After covalently cross-link, low molecular weight hyaluronic acid (LMW-HA) forms stable hydrogel that is important for film-forming process. By introducing a hydrolase gene, we constructed a  
<!--{cn}低分子量透明质酸(LMW-HA)共价交联后形成稳定的水凝胶,对成膜过程具有重要意义。通过引入水解酶基因,构建了一株能够生物合成LMW-HA的枯草芽孢杆菌菌株。-->
+
<!--{cn}低分子量透明质酸(LMW-HA)共价交联后形成稳定的水凝胶,对成膜过程具有重要意义。通过引入水解酶基因,构建了一株能够生物合成LMW-HA的-->
 +
<i>B. Subtilis<!--{cn}枯草芽孢杆菌--></i>
 +
strain that is able to biosynthesize LMW-HA.
 +
<!--{cn}菌株。-->
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<span class="before"></span>
 +
<span class="after"></span>
 
</div>
 
</div>
 
<div class="clearfix"></div>
 
<div class="clearfix"></div>
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<div class="col-xs-12 break original">
 
<div class="col-xs-12 break original">
<img src="img/home_break.png"/>
+
<img src="https://static.igem.org/mediawiki/2018/thumb/4/41/T--SSTi-SZGD--home_break.png/187px-T--SSTi-SZGD--home_break.png"/>
 
</div>
 
</div>
 
 
 
<!--paragraph 5-->
 
<!--paragraph 5-->
 
<div class="col-xs-12 paragraph five" style="text-align: center;">
 
<div class="col-xs-12 paragraph five" style="text-align: center;">
<div class="col-xs-12 img"></div>
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<div class="col-xs-12 col-sm-8 Cimg">
 +
<img src="https://static.igem.org/mediawiki/2018/thumb/4/40/T--SSTi-SZGD--home_hamp.png/800px-T--SSTi-SZGD--home_hamp.png"/>
 +
</div>
 
<div class="col-xs-12 content">
 
<div class="col-xs-12 content">
 
We developed a novel cosmetic product: HA Micro-Needle Patch !!!
 
We developed a novel cosmetic product: HA Micro-Needle Patch !!!
 
<!--{cn}我们开发了一种新型的化妆品:透明质酸微针贴片!!!-->
 
<!--{cn}我们开发了一种新型的化妆品:透明质酸微针贴片!!!-->
 +
<span class="before"></span>
 +
<span class="after"></span>
 
</div>
 
</div>
<div class="clearfix"></div>
 
 
</div>
 
</div>
 
 
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</section>
 
</section>
 
 
 
 
</div>
 
</div>
 
 
 +
<!--Footer-->
 +
<footer class="container-fluid page_footer">
 +
 +
<!--Sponsor-->
 +
<section class="Sponsor container">
 +
 +
<div class="col-xs-12">
 +
<img src="https://static.igem.org/mediawiki/2018/5/58/T--SSTi-SZGD--Sponsor.png"/>
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</div>
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</section>
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<!--page_copyright-->
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<section class="container-fluid page_copyright">
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Copyright © 2018 SSTi-SZGD All Rights Reserved.
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</section>
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</footer>
 
 
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</body>
 
</body>
  
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{{SSTi-SZGD/btn}}
 
{{SSTi-SZGD/btn}}
{{SSTi-SZGD/Footer}}
 

Latest revision as of 05:50, 2 November 2018

SSTi-SZGD
In our modern world, millions of people do not hesitate to spend a fortune to achieve younger looking and vibrant appearances, thus the cosmetic industry keeps growing.
Hyaluronic acid is one of the mostly used ingredients in cosmetic products, thanks to its exceptional water retention ability that helps rejuvenating skin and reducing wrinkles.
Hyaulornic acid production via microbial fermentation is generally through Streptococus species, which contains endotoxins. We constructed recombinant Bacillus subtilis , the food-grade safe species, to mass produce hyaluronic acid.
After covalently cross-link, low molecular weight hyaluronic acid (LMW-HA) forms stable hydrogel that is important for film-forming process. By introducing a hydrolase gene, we constructed a B. Subtilis strain that is able to biosynthesize LMW-HA.
We developed a novel cosmetic product: HA Micro-Needle Patch !!!