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</td><td></td><td>Interlab</td><td>Complete Interlab measurement study</td><td>We successfully took part in the Interlab measurement study and a page documenting our work can be found here</td></tr> | </td><td></td><td>Interlab</td><td>Complete Interlab measurement study</td><td>We successfully took part in the Interlab measurement study and a page documenting our work can be found here</td></tr> | ||
<tr><td>Silver</td><td> Validated Part</td><td>Add a successfully characterised new part to the BioBrick registry</td><td>To enable expression of pTet-controlled constructs in bacterial strains which do not endogenously express TetR, we added the bidirectional pTet promoter, BBa_K2757002, to the registry More information on the design and characterisation of this part can be found here.</td></tr> | <tr><td>Silver</td><td> Validated Part</td><td>Add a successfully characterised new part to the BioBrick registry</td><td>To enable expression of pTet-controlled constructs in bacterial strains which do not endogenously express TetR, we added the bidirectional pTet promoter, BBa_K2757002, to the registry More information on the design and characterisation of this part can be found here.</td></tr> | ||
− | <tr><td></td><td>Human Practices</td><td>Consider the wider implications of the project</td><td> | + | <tr><td></td><td>Human Practices</td><td>Consider the wider implications of the project</td><td> Throughout the project, we took steps to better understand the application, safety, and implementation of our design. In addition to our discussions with medical professionals and IBD patients we hosted a number of outreach events and investigated ethical issues associated with GMO probiotics. Read more about our work here.</td></tr> |
</td><td></td><td>Collaboration</td><td>Describe work completed by the team and others</td><td>Over the Summer, we worked with a range of iGEM teams from around the world, both inside and outside the lab. A summary of our collaborations can be found here.</td></tr> | </td><td></td><td>Collaboration</td><td>Describe work completed by the team and others</td><td>Over the Summer, we worked with a range of iGEM teams from around the world, both inside and outside the lab. A summary of our collaborations can be found here.</td></tr> | ||
<tr><td>Gold</td><td>Modelling</td><td>Construct a meaningful model of the system</td><td>As shown here, we created a model of the system in both the time and frequency domain. Our model was integral in highlighting the need for a dual feedback loop to to optimise the response.</td></tr> | <tr><td>Gold</td><td>Modelling</td><td>Construct a meaningful model of the system</td><td>As shown here, we created a model of the system in both the time and frequency domain. Our model was integral in highlighting the need for a dual feedback loop to to optimise the response.</td></tr> | ||
− | <tr><td></td><td>Integrated Human Practices</td><td> | + | <tr><td></td><td>Integrated Human Practices</td><td>Document how the project was guided by Human Practices</td><td>A variety of public surveys, patient interviews, and meetings with researchers helped both to guide further research and to shape our design. A notable contribution was the development of an inducible kill switch system to enhance the safety of our probiotic. More information can be found here.</td></tr> |
<tr><td></td><td>Part Improvement</td><td>Create and characterise a BioBrick part with a functional improvement on an existing BioBrick part.</td><td>We decided to redesign the Art-175/DsbA composite, BBa_K1659002, submitted by the 2015 Oxford iGEM team by linking it with a pTet promoter to create BBa_K2757001, a functional probiotic kill switch. Read more about it here..</td></tr> | <tr><td></td><td>Part Improvement</td><td>Create and characterise a BioBrick part with a functional improvement on an existing BioBrick part.</td><td>We decided to redesign the Art-175/DsbA composite, BBa_K1659002, submitted by the 2015 Oxford iGEM team by linking it with a pTet promoter to create BBa_K2757001, a functional probiotic kill switch. Read more about it here..</td></tr> | ||
</table></center> | </table></center> |
Revision as of 18:12, 17 October 2018
Medals
Medal | Requirement | Criteria | Fulfilment |
---|---|---|---|
Bronze | Registration | Complete registration and attend the Giant Jamboree | We successfully registered for iGEM and are looking forward to attending the Boston jamboree! |
Competition Deliverables | Poster, Judging Form, Wiki and Presentation | We have created a poster and presentation to exhibit at the Giant Jamboree, and our judging form can be found here. | |
Attributions | Describe work completed by the team and others | A page describing project attributions can be found here | Interlab | Complete Interlab measurement study | We successfully took part in the Interlab measurement study and a page documenting our work can be found here |
Silver | Validated Part | Add a successfully characterised new part to the BioBrick registry | To enable expression of pTet-controlled constructs in bacterial strains which do not endogenously express TetR, we added the bidirectional pTet promoter, BBa_K2757002, to the registry More information on the design and characterisation of this part can be found here. |
Human Practices | Consider the wider implications of the project | Throughout the project, we took steps to better understand the application, safety, and implementation of our design. In addition to our discussions with medical professionals and IBD patients we hosted a number of outreach events and investigated ethical issues associated with GMO probiotics. Read more about our work here. | Collaboration | Describe work completed by the team and others | Over the Summer, we worked with a range of iGEM teams from around the world, both inside and outside the lab. A summary of our collaborations can be found here. |
Gold | Modelling | Construct a meaningful model of the system | As shown here, we created a model of the system in both the time and frequency domain. Our model was integral in highlighting the need for a dual feedback loop to to optimise the response. |
Integrated Human Practices | Document how the project was guided by Human Practices | A variety of public surveys, patient interviews, and meetings with researchers helped both to guide further research and to shape our design. A notable contribution was the development of an inducible kill switch system to enhance the safety of our probiotic. More information can be found here. | |
Part Improvement | Create and characterise a BioBrick part with a functional improvement on an existing BioBrick part. | We decided to redesign the Art-175/DsbA composite, BBa_K1659002, submitted by the 2015 Oxford iGEM team by linking it with a pTet promoter to create BBa_K2757001, a functional probiotic kill switch. Read more about it here.. |