Sam Grainger (Talk | contribs) |
|||
Line 132: | Line 132: | ||
<p style="text-align:left"> </p> | <p style="text-align:left"> </p> | ||
− | <h3 class="brand-heading"> | + | <h3 class="brand-heading">Semantic Containment System</h3> |
− | <p class="intro-text"> | + | <p class="intro-text"> These parts collectively provide proof of concept for a semantic containment system that can prevent a horizontally transferred gene being read and expressed by any environmental cell that has picked it up. Our <a href="https://2018.igem.org/Team:Edinburgh_UG/Semantic_Containment_Modelling"> probability modelling </a> predicts that a gene that has 5 and 10 amber STOP codons substituted into the coding sequence will only be expressed 1 in every 10<sup>10</sup> and 1 in every 10<sup>18</sup> translation attempts. </p> |
<p style="text-align:left"> </p> | <p style="text-align:left"> </p> |
Revision as of 22:46, 17 October 2018
Part Collection
Semantic Containment System
These parts collectively provide proof of concept for a semantic containment system that can prevent a horizontally transferred gene being read and expressed by any environmental cell that has picked it up. Our probability modelling predicts that a gene that has 5 and 10 amber STOP codons substituted into the coding sequence will only be expressed 1 in every 1010 and 1 in every 1018 translation attempts.
Part number | Type | Description | Supporting information | Part length (bp) |
---|---|---|---|---|
BBa_K2725012 | Basic | KanR 5* | P1003 kanamycin resistance with 5 amber stop codons | 967 |
BBa_K2725013 | Basic | KanR 10* | P1003 kanamycin resistance with 10 amber stop codons | 967 |
BBa_K2725016 | Basic | J23108 - SupD | Serine amber suppressor tRNA gene under J23108 Anderson promoter | 224 |
Contact EdiGEM18
Feel free to leave us a comment on social media!