Difference between revisions of "Team:Utrecht/Results"
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| + | $("#menuLaboratory").addClass('active'); | ||
| + | defSubmenu = submenuLab; | ||
| + | defActive = '#submenuResults'; | ||
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| + | <div class = "customHeader2" id = "header"><img src="https://static.igem.org/mediawiki/2018/b/b3/T--Utrecht--2018-HeaderImprove.svg"></div> | ||
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| + | <div class = "customelementM5A" id = "Introduction"> | ||
| + | <p> DeTaXion is a bacterial-based sensor for the detection of pharmaceutical contaminants in surface water. In its final form, DeTaXion will consist of a series of bacteria that can detect a wide variety of compounds. This will be achieved by engineering the chemotaxis pathway of Escherichia coli to emit a visible light signal in response to different pharmaceutical compounds. The project consists of three main aims: | ||
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| + | Aim 1: Explore the possibility of using the ligand binding domains from different transmembrane receptors. | ||
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| + | Aim 2: Development of a Bioluminescence Resonance Energy Transfer (BRET) readout for the activity of the chemotaxis pathway. | ||
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| + | Aim 3: Adjusting the dynamic range of the chemotaxis system to enable detection of a broad range of contaminant concentrations. | ||
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| + | Below we describe the results in each of these aims, including a description of the successful use of our submitted parts BBa_K2736101 and BBa_K2736105. | ||
| + | </p> | ||
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| + | </div> | ||
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| + | <div class = "navigateArrows"> | ||
| + | <div class = "arrowLeft"> <a href="https://2018.igem.org/Team:Utrecht/Parts"><b class = "fa fa-angle-left"></b> Biobricks</a></div> | ||
| + | <div class = "arrowLeft"> <a href="https://2018.igem.org/Team:Utrecht/Design"><b class = "fa fa-angle-double-left"></b> Project Design</a></div> | ||
| + | <div class = "arrowRight"> <a href="https://2018.igem.org/Team:Utrecht/Results">Results <b class = "fa fa-angle-right"></b></a></div> | ||
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| + | </body> | ||
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| + | {{Utrecht/Footer}} | ||
Revision as of 20:44, 17 October 2018
DeTaXion is a bacterial-based sensor for the detection of pharmaceutical contaminants in surface water. In its final form, DeTaXion will consist of a series of bacteria that can detect a wide variety of compounds. This will be achieved by engineering the chemotaxis pathway of Escherichia coli to emit a visible light signal in response to different pharmaceutical compounds. The project consists of three main aims: Aim 1: Explore the possibility of using the ligand binding domains from different transmembrane receptors. Aim 2: Development of a Bioluminescence Resonance Energy Transfer (BRET) readout for the activity of the chemotaxis pathway. Aim 3: Adjusting the dynamic range of the chemotaxis system to enable detection of a broad range of contaminant concentrations. Below we describe the results in each of these aims, including a description of the successful use of our submitted parts BBa_K2736101 and BBa_K2736105.