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<p>Based on the results of the Testing and Modeling groups, we arrived at the following simple model for how StarCores function.</p> | <p>Based on the results of the Testing and Modeling groups, we arrived at the following simple model for how StarCores function.</p> | ||
+ | <br><li>StarCores act by destabilizing the bacterial membrane, similar to conventional AMPs.</li></br> | ||
<br><li>StarCore activity is mediated by a nonspecific mechanism, probably charge.</li></br> | <br><li>StarCore activity is mediated by a nonspecific mechanism, probably charge.</li></br> | ||
<li>AMP-Core fusions are difficult to express, probably because the do not fold well.</li></br> | <li>AMP-Core fusions are difficult to express, probably because the do not fold well.</li></br> |
Revision as of 23:44, 17 October 2018
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Box 1: Why are StarCore Proteins Difficult to Express? |
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Based on the results of the Testing and Modeling groups, we arrived at the following simple model for how StarCores function. |