Difference between revisions of "Team:Paris Bettencourt/Results"

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<li>The StarCores we have obtained show antimicrobial activity.</li>
 
<li>The StarCores we have obtained show antimicrobial activity.</li>
 
<li>8 out of the 10 constructs showed antimicrobial activity towards E. coli while 9 out of the 10 constructs displayed antimicrobial potential towards B. subtilis.</li>
 
<li>8 out of the 10 constructs showed antimicrobial activity towards E. coli while 9 out of the 10 constructs displayed antimicrobial potential towards B. subtilis.</li>
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<li>StarCores of varying geometry displayed similar MIC values.</li>
 
<li>StarCores of varying geometry displayed similar MIC values.</li>
 
<li>There was no clear correlation between the geometry of the StarCores and their antimicrobial activity, indicating a non-specific mechanism of action.</li>
 
<li>There was no clear correlation between the geometry of the StarCores and their antimicrobial activity, indicating a non-specific mechanism of action.</li>
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Revision as of 02:48, 18 October 2018

Key Results

Key results from the Testing

  • The StarCores we have obtained show antimicrobial activity.
  • 8 out of the 10 constructs showed antimicrobial activity towards E. coli while 9 out of the 10 constructs displayed antimicrobial potential towards B. subtilis.
  • The top performing StarCore was the Ferritin-Alyteserin fusion, with an activity almost 10 times higher than that of the control. Some StarCores exhibited species-specific killing, being particularly active against E. coli.
  • StarCores of varying geometry displayed similar MIC values.
  • There was no clear correlation between the geometry of the StarCores and their antimicrobial activity, indicating a non-specific mechanism of action.
    • Centre for Research and Interdisciplinarity (CRI)
    Faculty of Medicine Cochin Port-Royal, South wing, 2nd floor
    Paris Descartes University
    24, rue du Faubourg Saint Jacques
    75014 Paris, France
    paris-bettencourt-2018@cri-paris.org