Formaldehyde brings different degrees of harmful symptoms to us humans, such as eye, throat and skin irritation, and even carcinogenicity, which is widely used in construction and decoration industries. In previous iGEM projects related to formaldehyde, several problems still need to improve, such as 1) the present sensing threshold of formaldehyde concentration (~ 10 ppm) is far upper beyond the environment-protecting standard (~ 0.1 ppm); 2) the degrading system seems to work unstably, although some survival or duration after formaldehyde addition was observed. Our project is aiming to construct a more sensitive and effective E. coli-based system for detecting and further degrading formaldehyde in environments, basing on current systems (already registered as BioBrick parts).

Team:HFLS ZhejiangUnited

Welcome to iGEM 2018 HFLS ZhejiangUnited!

Formaldehyde Eliminator: Engineered Microbes for Detecting and Biodegrading of Formaldehyde