Mechanistic Modelling for the uninitiated
Why do Mathematical Modelling?
Synthetic Biology is a discipline with an inherantly large amount of unpredictability. There are many difficult to account for factors within the cell which can cause BioBrick parts to function in unexpected ways. In order to combat this uncertainty mathematical modelling techniques are often applied to make predictions about how BioBrick parts will operate to inform their design and characterisation before parts are obtained by DNA synthesis or other methods.
Modelling Methodology
A wide variety of modelling methodologies exist with adaptations to a miriad of different tasks. Here we would like to focus on the particular mechanistic modelling methodology that we applied in our DNA Degradation Switch, Semantic Containment Failure and Collaboration models.
Mass Action Equations
Ordinary Differential Equations
Contact EdiGEM18
Feel free to leave us a comment on social media!