Team:Paris Bettencourt/Results

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@iGEM_Paris

Key Results

Key results from the Testing

The StarCores we have obtained show antimicrobial activity.

8 out of the 10 constructs showed antimicrobial activity towards E. coli while 9 out of the 10 constructs displayed antimicrobial potential towards B. subtilis.

The top performing StarCore was the Ferritin-Alyteserin fusion, with an activity almost 10 times higher than that of the control. Some StarCores exhibited species-specific killing, being particularly active against E. coli.

StarCores of varying geometry displayed similar MIC values.

There was no clear correlation between the geometry of the StarCores and their antimicrobial activity, indicating a non-specific mechanism of action.

Centre for Research and Interdisciplinarity (CRI)
Faculty of Medicine Cochin Port-Royal, South wing, 2nd floor
Paris Descartes University
24, rue du Faubourg Saint Jacques
75014 Paris, France
paris-bettencourt-2018@cri-paris.org