Difference between revisions of "Team:NTHU Formosa/Description"

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  <li><a href="https://2018.igem.org/Team:NTHU_Formosa/test01">HOME</a>
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      <li><a href="https://2018.igem.org/Team:NTHU_Formosa/Project">Project</a>
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      <li><a href="https://2018.igem.org/Team:NTHU_Formosa/Experiment">Experiment</a>
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      <li><a href="https://2018.igem.org/Team:NTHU_Formosa/Human_Pratice">Human Pratice</a>
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      <li><a href="#">Team</a>
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      <li><a href="#">Modeling</a>
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  <li><a href="https://2018.igem.org/Team:NTHU_Formosa/Project">Project</a>
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  <li><a href="https://2018.igem.org/Team:NTHU_Formosa/Experiment">Experiment</a>
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  <li><a href="https://2018.igem.org/Team:NTHU_Formosa/Human_Pratice">Human Pratice</a>
  
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<h1>Description</h1>
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      <li><a href="https://2018.igem.org/Team:NTHU_Formosa/Conference">Conference</a>
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      <li><a href="https://2018.igem.org/Team:NTHU_Formosa/Industry">Industry</a>
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      <li><a href="https://2018.igem.org/Team:NTHU_Formosa/Academics">Academics</a>
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      <li><a href="https://2018.igem.org/Team:NTHU_Formosa/Public_Engagement">Public Engagement</a>
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      <li><a href="https://2018.igem.org/Team:NTHU_Formosa/Interlab">Interlab</a>
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<p>People around the world are growing awareness to their health condition. To
 
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monitor the health condition, a wide range of biomarkers-- special substances in the
 
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bloodstream representing the physiological and pathological states-- has been used in
 
  
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clinical diagnoses. Blood test is one of the most common way for detecting
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biomarkers but it suffers from several inevitable drawbacks such as invasiveness,
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  <li><a href="#">Team</a>
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time-consuming procedure, demand for medical staff service, non real-time tracking
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and so on. These disadvantages may discourage people from the periodic medical
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  <li><a href="#">Modeling</a>
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checkup. Indeed, according to a survey (of 1862 samples) pulled by our team, nearly
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half of the participants took blood test less than once a five-year frequency (Fig. 1),
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which is impractical for early detection and early treatment of diseases.
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<br>
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<div class="column full_size">
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  <h1>Description</h1>
  
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　To get rid of limits such as invasiveness and non real-time tracking, our team
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  <p>People around the world are growing awareness to their health condition. To monitor the health condition, a wide range of biomarkers-- special substances in the bloodstream representing the physiological and pathological states-- has been used in clinical
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proposed Biowatcher, engineered reporter cells that enable detection and autonomous
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    diagnoses. Blood test is one of the most common way for detecting biomarkers but it suffers from several inevitable drawbacks such as invasiveness, time-consuming procedure, demand for medical staff service, non real-time tracking and so on. These
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report of soluble biomarkers in bloodstream. The sensing parts of the reporter
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    disadvantages may discourage people from the periodic medical checkup. Indeed, according to a survey (of 1862 samples) pulled by our team, nearly half of the participants took blood test less than once a five-year frequency (Fig. 1), which is impractical
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cells are powered by nanobodies, the single-domain antibody that can be
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    for early detection and early treatment of diseases.
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engineered to detect different biomarkers. Binding of biomarkers on
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    <br> 　To get rid of limits such as invasiveness and non real-time tracking, our team proposed Biowatcher, engineered reporter cells that enable detection and autonomous report of soluble biomarkers in bloodstream. The sensing parts of the reporter cells
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nanobodies triggers our synthetic gene circuits and in turn induces
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    are powered by nanobodies, the single-domain antibody that can be engineered to detect different biomarkers. Binding of biomarkers on nanobodies triggers our synthetic gene circuits and in turn induces autonomous bioluminescent system as a readout
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autonomous bioluminescent system as a readout for devices to detect. This
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    for devices to detect. This kind of autonomous reporting system can have great varieties of application by installation on wearable devices, watch for example. With the required software (will be displayed at the giant jamboree?), the wearable devices
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kind of autonomous reporting system can have great varieties of application
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    could track the level of risk factors by measuring the bioluminescence intensity and record the data as numbers and graphs. It will send alert to users once the level of the risk factors is too high. Meanwhile, there will be suggestions of nearby
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by installation on wearable devices, watch for example. With the required
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    hospitals according to the users’ location. The system will also upload and attribute the data to public health analysis under the users’ consent.
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software (will be displayed at the giant jamboree?), the wearable devices
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    <br>
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could track the level of risk factors by measuring the bioluminescence
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intensity and record the data as numbers and graphs. It will send alert to
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users once the level of the risk factors is too high. Meanwhile, there will be
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suggestions of nearby hospitals according to the users’ location. The system
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will also upload and attribute the data to public health analysis under the
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users’ consent.
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<h3>What should this page contain?</h3>
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  <h3>What should this page contain?</h3>
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<li> A clear and concise description of your project.</li>
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    <li> A clear and concise description of your project.</li>
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<li>A detailed explanation of why your team chose to work on this particular project.</li>
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    <li>A detailed explanation of why your team chose to work on this particular project.</li>
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<li>References and sources to document your research.</li>
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    <li>References and sources to document your research.</li>
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<li>Use illustrations and other visual resources to explain your project.</li>
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    <li>Use illustrations and other visual resources to explain your project.</li>
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</ul>
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  </ul>
 
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<h3>Inspiration</h3>
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    <h3>Inspiration</h3>
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<p>See how other teams have described and presented their projects: </p>
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    <p>See how other teams have described and presented their projects: </p>
  
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<li><a href="https://2016.igem.org/Team:Imperial_College/Description">2016 Imperial College</a></li>
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      <li><a href="https://2016.igem.org/Team:Imperial_College/Description">2016 Imperial College</a></li>
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<li><a href="https://2016.igem.org/Team:Wageningen_UR/Description">2016 Wageningen UR</a></li>
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      <li><a href="https://2016.igem.org/Team:Wageningen_UR/Description">2016 Wageningen UR</a></li>
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<li><a href="https://2014.igem.org/Team:UC_Davis/Project_Overview"> 2014 UC Davis</a></li>
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      <li><a href="https://2014.igem.org/Team:UC_Davis/Project_Overview"> 2014 UC Davis</a></li>
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<li><a href="https://2014.igem.org/Team:SYSU-Software/Overview">2014 SYSU Software</a></li>
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      <li><a href="https://2014.igem.org/Team:SYSU-Software/Overview">2014 SYSU Software</a></li>
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  <h3>Advice on writing your Project Description</h3>
  
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    We encourage you to put up a lot of information and content on your wiki, but we also encourage you to include summaries as much as possible. If you think of the sections in your project description as the sections in a publication, you should try to
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    be concise, accurate, and unambiguous in your achievements.
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<h3>Advice on writing your Project Description</h3>
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<p>
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We encourage you to put up a lot of information and content on your wiki, but we also encourage you to include summaries as much as possible. If you think of the sections in your project description as the sections in a publication, you should try to be concise, accurate, and unambiguous in your achievements.  
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<h3>References</h3>
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  <h3>References</h3>
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<p>iGEM teams are encouraged to record references you use during the course of your research. They should be posted somewhere on your wiki so that judges and other visitors can see how you thought about your project and what works inspired you.</p>
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  <p>iGEM teams are encouraged to record references you use during the course of your research. They should be posted somewhere on your wiki so that judges and other visitors can see how you thought about your project and what works inspired you.</p>
  
 
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Revision as of 12:08, 18 September 2018

Description

People around the world are growing awareness to their health condition. To monitor the health condition, a wide range of biomarkers-- special substances in the bloodstream representing the physiological and pathological states-- has been used in clinical diagnoses. Blood test is one of the most common way for detecting biomarkers but it suffers from several inevitable drawbacks such as invasiveness, time-consuming procedure, demand for medical staff service, non real-time tracking and so on. These disadvantages may discourage people from the periodic medical checkup. Indeed, according to a survey (of 1862 samples) pulled by our team, nearly half of the participants took blood test less than once a five-year frequency (Fig. 1), which is impractical for early detection and early treatment of diseases.
　To get rid of limits such as invasiveness and non real-time tracking, our team proposed Biowatcher, engineered reporter cells that enable detection and autonomous report of soluble biomarkers in bloodstream. The sensing parts of the reporter cells are powered by nanobodies, the single-domain antibody that can be engineered to detect different biomarkers. Binding of biomarkers on nanobodies triggers our synthetic gene circuits and in turn induces autonomous bioluminescent system as a readout for devices to detect. This kind of autonomous reporting system can have great varieties of application by installation on wearable devices, watch for example. With the required software (will be displayed at the giant jamboree?), the wearable devices could track the level of risk factors by measuring the bioluminescence intensity and record the data as numbers and graphs. It will send alert to users once the level of the risk factors is too high. Meanwhile, there will be suggestions of nearby hospitals according to the users’ location. The system will also upload and attribute the data to public health analysis under the users’ consent.

What should this page contain?

  • A clear and concise description of your project.
  • A detailed explanation of why your team chose to work on this particular project.
  • References and sources to document your research.
  • Use illustrations and other visual resources to explain your project.

Inspiration

See how other teams have described and presented their projects:

Advice on writing your Project Description

We encourage you to put up a lot of information and content on your wiki, but we also encourage you to include summaries as much as possible. If you think of the sections in your project description as the sections in a publication, you should try to be concise, accurate, and unambiguous in your achievements.

References

iGEM teams are encouraged to record references you use during the course of your research. They should be posted somewhere on your wiki so that judges and other visitors can see how you thought about your project and what works inspired you.