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Revision as of 14:24, 2 October 2018
//小标题
Attribution
What makes Alpha Ant meaningful and wonderful is those people’s great work.
Since we are from different majors, all things can be covered by everyone of us. More information about team members could be found in Team.Generally, we have three main sessions: biology logic thinking and investigation, programming and modeling, design.
It’s more like a workflow. At first, everyone is engaged in previous biology research and decide to do a topic about pathway design. Secondly, biology group try to get access to different database and deliver data to programming group. Then data processing and main part programming are followed. At last, design group can figure out how to show our software reasonably and wiki design.
It’s more like a workflow. At first, everyone is engaged in previous biology research and decide to do a topic about pathway design. Secondly, biology group try to get access to different database and deliver data to programming group. Then data processing and main part programming are followed. At last, design group can figure out how to show our software reasonably and wiki design.
overview
Previous Research
Haiyan He, Xiaotian Yu, Zhichao Ma and Wei Cao are responsible for learning synthetic biology and mining proper topic.
Wei Cao investigated the barriers that experimenters could occur in metabolic engineering and interviewed Professor Ping Li for Tongji University for general workflow of metabolic pathway research.
Zhichao Ma communicated with postgraduate students major in bioinformatics.
Xiangzhen Li did some research on graph theoretic algorithm.
Database
Xiaotian Yu, Xiangzhen Li and Zhichao Ma were responsible for getting data from KEGG Database and data processing.
Haiyan He and Xiaotian Yu were responsible for calculating thermodynamic data by using equilibrator.
Zhichao Ma and Wei Cao was responsible for getting data from Brenda, ChEBI, DrugBank and KnowledgeBase.
Search algorithm & Ranking criteria
Xiangzhen Li did a lot of research on Graph Theoretic Algorithm and wrote code of DFS.
Xiaotian Yu and Wei Cao read some paper about atom conservation. Then they worked together on coding and model building.
Xiaotian Yu and Zhichao Ma worked on toxicity of compound and added it to ranking criteria.
Additional Functions
FBA
Wei Cao and Haiyan He learned COBRA toolbox and built FBA model.
Microorganism recommendation
Zhichao Ma and Xiangzhen Li built and optimized microorganism recommendation model.
SMILES Comparison
Xiaotian Yu learned RDkit toolbox and added SMILES Comparison to our project.
Design
Yuchen Xing, Yuejia Li were responsible for wiki design.
Yuchen Xing, Wei Cao and Zhichao Ma designed software interface.
YueJia Li also carried poster design work.
Human Practice and Collaboration
Visiting WuXi AppTec
Wei Cao communicated with WuXi AppTec and made an interview on experts in WuXi AppTec. Haiyan He, Xiaotian Yu, Zhichao Ma and Xiangzhen Li participated this interview and proposed many great ideas. Haiyan He give an excellent speech on this meeting.
Communicate with programmers
Zhichao Ma made a speech on a forum in school of life science and technology, Tongji University. There, we got a lot of suggestions on modeling.
Contact with experimenters
Wei Cao made a speech on professor Ping Li’s class and then investigate need of experimenters.
EuroAsia Meetup
All members attended EuroAsia Meetup in Shenzhen, China. Haiyan took picture for us. Wei Cao and Xiaotian Yu did presentation in this Meetup.
CCiC
Xiaotian Yu contacted with Shanghai-tech, who held CCiC in Shanghai.
Xiangzhen Li , Xiaotian Yu and Wei Cao gave the committee a great presentation.
Meeting with SJTU
Wei Cao contacted with SJTU-software and helped arrange meeting with SJTU-software. And rest of the team attended this meeting.
Game : “Go Ant!”
Xiaotian Yu developed the whole game. Of course, the rest of teammates gave him some advice. Yuejia Li designed the magnificent background, which made the game even more fun!
Financing
Xiaotian Yu is in charge of Financial management.
Trip planning
Wei Cao is responsible for flight tickets booking and hotel reservation. The rest of team members help plan the whole trip.
Advice and human practice support
Professor Qi Liu gave us advice on search algorithm and help us contact with WuXi AppTec.
Professor Ping Li taught us basic knowledge of synthetic biology and introduced MEIHUA GROUP to us. Then we visited the company and got a lot of useful comments on our software.
Associate professor Ye Len helped us make a speech in The first affiliated middle school of Tongji University.
We are sincerely grateful to everyone who help us in many ways.