Difference between revisions of "Team:NTU-Singapore"

 
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<a class="navbar-brand logo-margin" href="https://2018.igem.org/Team:NTU-Singapore"><img src="img/lazyload-ph.png" data-src="https://static.igem.org/mediawiki/2018/2/2b/T--NTU-Singapore--Logo.png" alt="logo" width="150" height="42" class="lazyload" style="margin-top: 17px;"/></a>
 
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<a href="https://2018.igem.org/Team:NTU-Singapore" style="padding-top: 17px; color:white">Home</a>
 
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<a href="https://2018.igem.org/Team:NTU-Singapore/Collaborations">Collaborations</a>
 
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<img src="img/lazyload-ph.png" data-src="https://static.igem.org/mediawiki/2018/3/3e/T--NTU-Singapore--Logo_Eye.png" class="center-block mg-sm hero-break img-responsive lazyload" width="500" srcset="img/Eye%20Structure.png 2x, img/Eye%20Structure.png 3x" style="padding-top: 10px;"/><img src="img/lazyload-ph.png" data-src="https://static.igem.org/mediawiki/2018/2/2b/T--NTU-Singapore--Logo.png" class="center-block mg-lg img-responsive logo-break lazyload" width="218" height="38" />
 
<h1 class="text-center mg-md tc-white  ">
 
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A CRISPR/Cas Base-Editing Toolkit
 
A CRISPR/Cas Base-Editing Toolkit
 
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From Genome to Transcriptome, From Detection to Modification.
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From Genome to Transcriptome, From Modification to Detection.
 
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Human-Centred Research
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Human-Centered Research
 
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Our research involves not only the students and scientists, but also the Singapore public. While doing our project, we looked into the public opinions towards gene editing. Our human practice tells how&nbsp;our project evolved around the local community that we live in.&nbsp;
 
Our research involves not only the students and scientists, but also the Singapore public. While doing our project, we looked into the public opinions towards gene editing. Our human practice tells how&nbsp;our project evolved around the local community that we live in.&nbsp;
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</p><a href="https://2018.igem.org/Team:NTU-Singapore/IHP" class="btn btn-wire btn-rd">Integrated Human Practice</a>
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</p><a href="https://2018.igem.org/Team:NTU-Singapore/Human_Practices" class="btn btn-wire btn-rd">Integrated Human Practice</a>
 
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CRISPR/Cas13b RNA Base Editor
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CRISPR/Cas13 RNA Base Editor
 
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As we have learnt through our interviews with medical doctors and interaction with the public, it is evident that RNA editing is more promising and better accep-ted in our society. Hence, we reflected on our project and ventured into RNA editing.
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As we have learnt through our interviews with medical doctors and interaction with the public, it is evident that RNA editing is a hidden gem of gene therapy that awaits to be explored. Hence, we evolved our project and ventured into RNA editing.
 
</p><a href="https://2018.igem.org/Team:NTU-Singapore/RNA" class="btn btn-wire btn-rd pull-left">Proejct REPAIR</a>
 
</p><a href="https://2018.igem.org/Team:NTU-Singapore/RNA" class="btn btn-wire btn-rd pull-left">Proejct REPAIR</a>
 
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Aim Even Higher.
 
Aim Even Higher.
 
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Modification-Sensitive&nbsp;Nanopore Sequencing
 
Modification-Sensitive&nbsp;Nanopore Sequencing
 
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To address the significant concern around the safety of RNA editing technology, we designed an unbiased, accurate RNA sequencing tool. Expanding the nanopore sequencing platform, we hope to enhance the saftey of RNA editing.
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To address the public concerns around RNA editing technology, we designed an unbiased, accurate RNA sequencing tool. Expanding the nanopore sequencing platform, we hope to enhance the safety of RNA editing and reduce its cost.
 
</p><a href="https://2018.igem.org/Team:NTU-Singapore/Nanopore" class="btn btn-wire btn-rd pull-left">Project Nanopore</a>
 
</p><a href="https://2018.igem.org/Team:NTU-Singapore/Nanopore" class="btn btn-wire btn-rd pull-left">Project Nanopore</a>
 
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Latest revision as of 18:48, 17 October 2018

Home

A Continuation and Beyond.

CRISPR/Cas9 DNA Base Editor

With the successful truncated dCas9-mediated transcriptional activation last year, we moved further this year into DNA base editing using CRISPR/Cas9 system. We also improved our truncated dCas9 further with novel strategies for higher binding efficiency.

Project Editor

Human-Centered Research

Our research involves not only the students and scientists, but also the Singapore public. While doing our project, we looked into the public opinions towards gene editing. Our human practice tells how our project evolved around the local community that we live in. 

Integrated Human Practice

Adapt to Change.

CRISPR/Cas13 RNA Base Editor

As we have learnt through our interviews with medical doctors and interaction with the public, it is evident that RNA editing is a hidden gem of gene therapy that awaits to be explored. Hence, we evolved our project and ventured into RNA editing.

Proejct REPAIR

Aim Even Higher.

Modification-Sensitive Nanopore Sequencing

To address the public concerns around RNA editing technology, we designed an unbiased, accurate RNA sequencing tool. Expanding the nanopore sequencing platform, we hope to enhance the safety of RNA editing and reduce its cost.

Project Nanopore