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<h1>Achievements</h1> | <h1>Achievements</h1> | ||
+ | <div> <h3>Dry lab </h3> | ||
+ | <ul> | ||
+ | <li>Developed an electrochemical model which simulates oxidised or reduced species being formed at and diffusing away from an electrode surface</li> | ||
+ | <li>Developed a biological model which simulates the genetic response to the concentration of oxidised and reduced species on a single cell level</li> | ||
+ | <li>Developed an integrated model and fitted it to experimental data to estimate absolute parameters of the electrogenetic system</li> | ||
+ | <li>Designed and constructed an affordable electrode array to facilitate programmable spatial using the electrogenetic device. </li> | ||
+ | <li>Developed a user-friendly phone application for remote control of patterning using the electrode array. </li> | ||
+ | </ul> | ||
+ | |||
+ | |||
+ | <h3>Wet lab </h3> | ||
+ | <ul> | ||
+ | |||
+ | <li>Generated the first aerobic electrogenetic device in <i>E. coli </i></li> | ||
+ | <li>Optimised chemical conditions of the system to maximise the biological response of the electrogenetic device without significantly impacting cell viability. </li> | ||
+ | <li>Proved this electrogenetic can provide fine spatial control of gene expression using a cheap electrode set-up. </li> | ||
+ | <li>Created a library of electrogenetic parts for use in future electrogenetic project. </li> | ||
+ | <li>Assembled the electrogenetic library into X different constructs using the next-generation BASIC assembly method, which were then characterised. </li> | ||
+ | <li>Proved applications of electrogenetic devices in biocontainment and biomanifacturing. </li> | ||
+ | <li>Found evidence of a new phenazine molecule as an inducer, which was suggested to exist in prior literature. </li> | ||
+ | </ul> | ||
+ | |||
+ | <h3>Human practices and outreach </h3> | ||
+ | <ul> | ||
+ | <li>Proved molecules in the system could be replaced with safer alternatives following experts’ concerns of the toxicity of the system. </li> | ||
+ | <li>Designed a Communinication Strategy Guide (CSG) to direct communication of our project with stakeholders</li> | ||
+ | <li>Desined an interactive app (LTAT) to foster communication of problems within a team</li> | ||
+ | </ul> | ||
+ | |||
+ | <h3>Collaborations </h3> | ||
+ | <ul> | ||
+ | <li>Collaborated with X different teams from X different countries.</li> | ||
+ | <li>Proved the part library can be used for alternative devices to electrogenetic systems with Oxford University.</li> | ||
+ | <li>Ensured comparability of the part library with multiple assembly methods with Oxford University</li> | ||
+ | </ul> | ||
+ | |||
+ | |||
<br/> | <br/> | ||
<br/> | <br/> |
Revision as of 23:41, 17 October 2018
Achievements
Dry lab
- Developed an electrochemical model which simulates oxidised or reduced species being formed at and diffusing away from an electrode surface
- Developed a biological model which simulates the genetic response to the concentration of oxidised and reduced species on a single cell level
- Developed an integrated model and fitted it to experimental data to estimate absolute parameters of the electrogenetic system
- Designed and constructed an affordable electrode array to facilitate programmable spatial using the electrogenetic device.
- Developed a user-friendly phone application for remote control of patterning using the electrode array.
Wet lab
- Generated the first aerobic electrogenetic device in E. coli
- Optimised chemical conditions of the system to maximise the biological response of the electrogenetic device without significantly impacting cell viability.
- Proved this electrogenetic can provide fine spatial control of gene expression using a cheap electrode set-up.
- Created a library of electrogenetic parts for use in future electrogenetic project.
- Assembled the electrogenetic library into X different constructs using the next-generation BASIC assembly method, which were then characterised.
- Proved applications of electrogenetic devices in biocontainment and biomanifacturing.
- Found evidence of a new phenazine molecule as an inducer, which was suggested to exist in prior literature.
Human practices and outreach
- Proved molecules in the system could be replaced with safer alternatives following experts’ concerns of the toxicity of the system.
- Designed a Communinication Strategy Guide (CSG) to direct communication of our project with stakeholders
- Desined an interactive app (LTAT) to foster communication of problems within a team
Collaborations
- Collaborated with X different teams from X different countries.
- Proved the part library can be used for alternative devices to electrogenetic systems with Oxford University.
- Ensured comparability of the part library with multiple assembly methods with Oxford University