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<h1>Achievements</h1> | <h1>Achievements</h1> | ||
<div> <h3>Dry lab </h3> | <div> <h3>Dry lab </h3> | ||
− | < | + | <p> |
− | + | - Developed an electrochemical model which simulates oxidised or reduced species being formed at and diffusing away from an electrode surface | |
− | + | - Developed a biological model which simulates the genetic response to the concentration of oxidised and reduced species on a single cell level | |
− | + | - Developed an integrated model and fitted it to experimental data to estimate absolute parameters of the electrogenetic system | |
− | + | - Designed and constructed an affordable electrode array to facilitate programmable spatial using the electrogenetic device. | |
− | + | - Developed a user-friendly phone application for remote control of patterning using the electrode array. | |
− | </ | + | </p> |
<h3>Wet lab </h3> | <h3>Wet lab </h3> | ||
− | < | + | <p> |
− | + | - Generated the first aerobic electrogenetic device in <i>E. coli </i> | |
− | + | - Optimised chemical conditions of the system to maximise the biological response of the electrogenetic device without significantly impacting cell viability. | |
− | + | - Proved this electrogenetic can provide fine spatial control of gene expression using a cheap electrode set-up. | |
− | + | - Created a library of electrogenetic parts for use in future electrogenetic project. | |
− | + | - Assembled the electrogenetic library into X different constructs using the next-generation BASIC assembly method, which were then characterised. | |
− | + | - Proved applications of electrogenetic devices in biocontainment and biomanifacturing. | |
− | + | - Found evidence of a new phenazine molecule as an inducer, which was suggested to exist in prior literature. | |
− | </ | + | </p> |
<h3>Human practices and outreach </h3> | <h3>Human practices and outreach </h3> | ||
− | < | + | <p> |
− | + | - Proved molecules in the system could be replaced with safer alternatives following experts’ concerns of the toxicity of the system. | |
− | + | - Designed a Communinication Strategy Guide (CSG) to direct communication of our project with stakeholders | |
− | + | - Desined an interactive app (LTAT) to foster communication of problems within a team | |
− | </ | + | </p> |
<h3>Collaborations </h3> | <h3>Collaborations </h3> | ||
− | < | + | <p> |
− | + | - Collaborated with X different teams from X different countries. | |
− | + | - Proved the part library can be used for alternative devices to electrogenetic systems with Oxford University. | |
− | + | - Ensured comparability of the part library with multiple assembly methods with Oxford University | |
− | </ | + | </p> |
Revision as of 23:49, 17 October 2018
Achievements
Dry lab
- Developed an electrochemical model which simulates oxidised or reduced species being formed at and diffusing away from an electrode surface - Developed a biological model which simulates the genetic response to the concentration of oxidised and reduced species on a single cell level - Developed an integrated model and fitted it to experimental data to estimate absolute parameters of the electrogenetic system - Designed and constructed an affordable electrode array to facilitate programmable spatial using the electrogenetic device. - Developed a user-friendly phone application for remote control of patterning using the electrode array.
Wet lab
- Generated the first aerobic electrogenetic device in E. coli - Optimised chemical conditions of the system to maximise the biological response of the electrogenetic device without significantly impacting cell viability. - Proved this electrogenetic can provide fine spatial control of gene expression using a cheap electrode set-up. - Created a library of electrogenetic parts for use in future electrogenetic project. - Assembled the electrogenetic library into X different constructs using the next-generation BASIC assembly method, which were then characterised. - Proved applications of electrogenetic devices in biocontainment and biomanifacturing. - Found evidence of a new phenazine molecule as an inducer, which was suggested to exist in prior literature.
Human practices and outreach
- Proved molecules in the system could be replaced with safer alternatives following experts’ concerns of the toxicity of the system. - Designed a Communinication Strategy Guide (CSG) to direct communication of our project with stakeholders - Desined an interactive app (LTAT) to foster communication of problems within a team
Collaborations
- Collaborated with X different teams from X different countries. - Proved the part library can be used for alternative devices to electrogenetic systems with Oxford University. - Ensured comparability of the part library with multiple assembly methods with Oxford University