Difference between revisions of "Team:Imperial College/Achievements"
| Line 45: | Line 45: | ||
<p> | <p> | ||
- Developed an electrochemical model which simulates oxidised or reduced species being formed at and diffusing away from an electrode surface | - Developed an electrochemical model which simulates oxidised or reduced species being formed at and diffusing away from an electrode surface | ||
| + | </p><p> | ||
- Developed a biological model which simulates the genetic response to the concentration of oxidised and reduced species on a single cell level | - Developed a biological model which simulates the genetic response to the concentration of oxidised and reduced species on a single cell level | ||
| − | - Developed an integrated model and fitted it to experimental data to estimate absolute parameters of the electrogenetic system | + | </p><p> |
| + | - Developed an integrated model and fitted it to experimental data to estimate absolute parameters of the electrogenetic system | ||
| + | </p><p> | ||
- Designed and constructed an affordable electrode array to facilitate programmable spatial using the electrogenetic device. | - Designed and constructed an affordable electrode array to facilitate programmable spatial using the electrogenetic device. | ||
| + | </p><p> | ||
- Developed a user-friendly phone application for remote control of patterning using the electrode array. | - Developed a user-friendly phone application for remote control of patterning using the electrode array. | ||
</p> | </p> | ||
| Line 54: | Line 58: | ||
<h3>Wet lab </h3> | <h3>Wet lab </h3> | ||
<p> | <p> | ||
| − | + | - Generated the first aerobic electrogenetic device in <i>E. coli </I> | |
| − | - Generated the first aerobic electrogenetic device in <i>E. coli </ | + | </p><p> |
| − | - Optimised chemical conditions of the system to maximise the biological response of the electrogenetic device without significantly impacting cell viability. | + | - Optimised chemical conditions of the system to maximise the biological response of the electrogenetic device without significantly impacting cell viability. </p><p> |
| − | - Proved this electrogenetic can provide fine spatial control of gene expression using a cheap electrode set-up. | + | - Proved this electrogenetic can provide fine spatial control of gene expression using a cheap electrode set-up. </p><p> |
| − | - Created a library of electrogenetic parts for use in future electrogenetic project. | + | - Created a library of electrogenetic parts for use in future electrogenetic project. </p><p> |
| − | - Assembled the electrogenetic library into X different constructs using the next-generation BASIC assembly method, which were then characterised. | + | - Assembled the electrogenetic library into X different constructs using the next-generation BASIC assembly method, which were then characterised. </p><p> |
| − | - Proved applications of electrogenetic devices in biocontainment and biomanifacturing. | + | - Proved applications of electrogenetic devices in biocontainment and biomanifacturing. </p><p> |
- Found evidence of a new phenazine molecule as an inducer, which was suggested to exist in prior literature. | - Found evidence of a new phenazine molecule as an inducer, which was suggested to exist in prior literature. | ||
</p> | </p> | ||
| Line 66: | Line 70: | ||
<h3>Human practices and outreach </h3> | <h3>Human practices and outreach </h3> | ||
<p> | <p> | ||
| − | - Proved molecules in the system could be replaced with safer alternatives following experts’ concerns of the toxicity of the system. | + | - Proved molecules in the system could be replaced with safer alternatives following experts’ concerns of the toxicity of the system. </p><p> |
| − | - Designed a Communinication Strategy Guide (CSG) to direct communication of our project with stakeholders | + | - Designed a Communinication Strategy Guide (CSG) to direct communication of our project with stakeholders</p><p> |
- Desined an interactive app (LTAT) to foster communication of problems within a team | - Desined an interactive app (LTAT) to foster communication of problems within a team | ||
</p> | </p> | ||
| Line 73: | Line 77: | ||
<h3>Collaborations </h3> | <h3>Collaborations </h3> | ||
<p> | <p> | ||
| − | - Collaborated with X different teams from X different countries. | + | - Collaborated with X different teams from X different countries.</p><p> |
| − | - Proved the part library can be used for alternative devices to electrogenetic systems with Oxford University. | + | - Proved the part library can be used for alternative devices to electrogenetic systems with Oxford University.</p><p> |
- Ensured comparability of the part library with multiple assembly methods with Oxford University | - Ensured comparability of the part library with multiple assembly methods with Oxford University | ||
</p> | </p> | ||
Revision as of 23:50, 17 October 2018
Achievements
Dry lab
- Developed an electrochemical model which simulates oxidised or reduced species being formed at and diffusing away from an electrode surface
- Developed a biological model which simulates the genetic response to the concentration of oxidised and reduced species on a single cell level
- Developed an integrated model and fitted it to experimental data to estimate absolute parameters of the electrogenetic system
- Designed and constructed an affordable electrode array to facilitate programmable spatial using the electrogenetic device.
- Developed a user-friendly phone application for remote control of patterning using the electrode array.
Wet lab
- Generated the first aerobic electrogenetic device in E. coli
- Optimised chemical conditions of the system to maximise the biological response of the electrogenetic device without significantly impacting cell viability.
- Proved this electrogenetic can provide fine spatial control of gene expression using a cheap electrode set-up.
- Created a library of electrogenetic parts for use in future electrogenetic project.
- Assembled the electrogenetic library into X different constructs using the next-generation BASIC assembly method, which were then characterised.
- Proved applications of electrogenetic devices in biocontainment and biomanifacturing.
- Found evidence of a new phenazine molecule as an inducer, which was suggested to exist in prior literature.
Human practices and outreach
- Proved molecules in the system could be replaced with safer alternatives following experts’ concerns of the toxicity of the system.
- Designed a Communinication Strategy Guide (CSG) to direct communication of our project with stakeholders
- Desined an interactive app (LTAT) to foster communication of problems within a team
Collaborations
- Collaborated with X different teams from X different countries.
- Proved the part library can be used for alternative devices to electrogenetic systems with Oxford University.
- Ensured comparability of the part library with multiple assembly methods with Oxford University
BRONZE
SILVER
GOLD
