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<h1>Achievements</h1> | <h1>Achievements</h1> | ||
− | <div> <h3>Dry lab </h3> | + | |
+ | <div> | ||
+ | <p>During these months we worked, had fun, made new friends and also achieved great things. </p> | ||
+ | <h3>Dry lab </h3> | ||
<p> | <p> | ||
- Developed an electrochemical model which simulates oxidised or reduced species being formed at and diffusing away from an electrode surface | - Developed an electrochemical model which simulates oxidised or reduced species being formed at and diffusing away from an electrode surface | ||
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<img src="https://static.igem.org/mediawiki/2018/9/9e/T--Imperial_College--bronze.png"alt="" width="10%";> | <img src="https://static.igem.org/mediawiki/2018/9/9e/T--Imperial_College--bronze.png"alt="" width="10%";> | ||
<p2>criteria for bronze medal</p2> | <p2>criteria for bronze medal</p2> | ||
− | <p> ✔ | + | <p> ✔ We registered for the Giant Jamboree and are excited to go there </p> |
− | <p> ✔ | + | <p> ✔ We contacted advisors, collaborators, sponsors and supporters and attributed their work on out attributions page <a href="https://2018.igem.org/Team:Imperial_College/Attributions" target="blank">Attributions </a> </p> |
− | <p> ✔ | + | <p> ✔ We have submitted a comprehensive judging form and wiki and finalised our poster and presentation on time for the Jamboree. <a href="https://igem.org/2018_Judging_Form?id=2862" target="blank">Judging form </a></p> |
− | <p> ✔ | + | <p> ✔ We improved gp2 T7 small protein (<a href="http://parts.igem.org/Part:BBa_K1893019" target="blank">BBa_ K1893019 </a>) characterisation using our electric activation system. </p> |
</div> | </div> |
Revision as of 00:52, 18 October 2018
Achievements
During these months we worked, had fun, made new friends and also achieved great things.
Dry lab
- Developed an electrochemical model which simulates oxidised or reduced species being formed at and diffusing away from an electrode surface
- Developed a biological model which simulates the genetic response to the concentration of oxidised and reduced species on a single cell level
- Developed an integrated model and fitted it to experimental data to estimate absolute parameters of the electrogenetic system
- Designed and constructed an affordable electrode array to facilitate programmable spatial using the electrogenetic device.
- Developed a user-friendly phone application for remote control of patterning using the electrode array.
Wet lab
- Generated the first aerobic electrogenetic device in E. coli
- Optimised chemical conditions of the system to maximise the biological response of the electrogenetic device without significantly impacting cell viability.
- Proved this electrogenetic can provide fine spatial control of gene expression using a cheap electrode set-up.
- Created a library of electrogenetic parts for use in future electrogenetic project.
- Assembled the electrogenetic library into X different constructs using the next-generation BASIC assembly method, which were then characterised.
- Proved applications of electrogenetic devices in biocontainment and biomanifacturing.
- Found evidence of a new phenazine molecule as an inducer, which was suggested to exist in prior literature.
Human practices and outreach
- Proved molecules in the system could be replaced with safer alternatives following experts’ concerns of the toxicity of the system.
- Designed a Communinication Strategy Guide (CSG) to direct communication of our project with stakeholders
- Desined an interactive app (LTAT) to foster communication of problems within a team
Collaborations
- Collaborated with X different teams from X different countries.
- Proved the part library can be used for alternative devices to electrogenetic systems with Oxford University.
- Ensured comparability of the part library with multiple assembly methods with Oxford University
BRONZE
✔ We registered for the Giant Jamboree and are excited to go there
✔ We contacted advisors, collaborators, sponsors and supporters and attributed their work on out attributions page Attributions
✔ We have submitted a comprehensive judging form and wiki and finalised our poster and presentation on time for the Jamboree. Judging form
✔ We improved gp2 T7 small protein (BBa_ K1893019 ) characterisation using our electric activation system.
SILVER
✔ Registration for Jamboree and Jamboree attendance done
✔ Registration for Jamboree and Jamboree attendance done
✔ Registration for Jamboree and Jamboree attendance done
GOLD
✔ Registration for Jamboree and Jamboree attendance done
✔ Registration for Jamboree and Jamboree attendance done
✔ Registration for Jamboree and Jamboree attendance done
✔ Registration for Jamboree and Jamboree attendance done