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</style> | </style> | ||
− | < | + | <div class="bg"></div> |
− | <h6><b> | + | |
+ | <body> | ||
+ | <br> | ||
+ | <h6><b>Integrated Human Practices</b></h6> | ||
+ | |||
+ | <div> | ||
+ | <h2>Our primary goal was to build a tool that enables users to check the safety of the food and water they might consume. We started off with the device as a wearable for travelers, who often fall victim to foodborne diseases. Extensive interviews, however, with possible users ranging from food vendors, travelers, pregnant women, to health professionals across 4 continents showed the device's wider potential contribution. The wearable then became a pen-and-holder to allow for this diverse usage while the casing color and material changed to accommodate various environments. Interactions with UAE and Bosnian government institutions prompted us to think about benefits to government and public agencies as well. The Quality Control Centre, Abu Dhabi Food Control Authority, and Institute of Public Health in Bosnia alongside food analysts indicated a niche in rapid food inspection and analysis that our device could fill upon refinement. Refinement meant integrating a faster DNA amplification technique operating at a lower temperature without sacrificing specificity. The device also had to be compact and safe to handle following discussions with health ethnologists and NGOs. The World Health Organization and our very own Vice Provost for Global Education made us realize the project as a start of a global health network. The device was designed in a way to be as neutral as possible to diverse cultural and social environments, with the idea of developing future plans for worldwide educational resources coupled with the distribution of the device. It has been clear to us that problems in global health cannot only be solved by using new biological and engineering integration but also social and educational progress. We are proud that <i>Pathogene</i> provides a new and unique guarantee for food safety on individual, communal, and governmental levels as a result of our integrated human practices. Please note that the interviews conducted with target groups have been IRB approved. | ||
+ | </h2> | ||
+ | </div> | ||
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+ | <br> | ||
+ | <br> | ||
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+ | <center><img src="https://static.igem.org/mediawiki/2018/5/5a/T--NYU_Abu_Dhabi--Integrated_Human_Practices--design.png" alt="Workplace" width="1000" position="relative" /></center> | ||
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+ | <div class="content"> | ||
+ | <div class="content-inside"> | ||
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+ | <div class="center"><font size="6">Expert Counsel</font></div> | ||
+ | <hr> | ||
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<h2> Clinical laboratories are at the center of the health providers’ analysis of food pathogens. Currently, the fastest tools they possess are PCR-based and take over 6 hours with per-sample price of over 100$. Less financially supported hospitals and healthcare providers might have to depend on machines that take several days. The more rapid the result is, the faster the response the clinical laboratory can provide to physicians and others. Bacterial pathogens of note in the region of Abu Dhabi are Campylobacter and Shigella. Devices used in the laboratory are provided for free by the manufacturers and they are recharged for the biological buffer and reagents. </h2> | <h2> Clinical laboratories are at the center of the health providers’ analysis of food pathogens. Currently, the fastest tools they possess are PCR-based and take over 6 hours with per-sample price of over 100$. Less financially supported hospitals and healthcare providers might have to depend on machines that take several days. The more rapid the result is, the faster the response the clinical laboratory can provide to physicians and others. Bacterial pathogens of note in the region of Abu Dhabi are Campylobacter and Shigella. Devices used in the laboratory are provided for free by the manufacturers and they are recharged for the biological buffer and reagents. </h2> | ||
</div> | </div> | ||
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<h2> The device could be a first step in creating an integrated network across the world, providing low-income communities not only with much higher food safety, but coupled with educational programs, providing them also with the skills they need to take it even further. Reaching out to local members of the community can make the device a household name and increase trust, not just in the device, but also in the NGOs working on the field. To this end, collaboration with already developed on-the-ground NGOs is a great window into integrating the device into the communities. Therefore, with centers around the world working on feedback and education of the device, it can make an even bigger contribution to global health. </h2> | <h2> The device could be a first step in creating an integrated network across the world, providing low-income communities not only with much higher food safety, but coupled with educational programs, providing them also with the skills they need to take it even further. Reaching out to local members of the community can make the device a household name and increase trust, not just in the device, but also in the NGOs working on the field. To this end, collaboration with already developed on-the-ground NGOs is a great window into integrating the device into the communities. Therefore, with centers around the world working on feedback and education of the device, it can make an even bigger contribution to global health. </h2> | ||
</div> | </div> | ||
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<div id='akpaka'> | <div id='akpaka'> | ||
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<h2> Dr. Akpaka informed us about the impact Salmonella and pathogenic E. Coli have on the communities on Trinidad, encasing our project as one of global impact. Current highest-class toxin identifiers take 30 minutes with the devices being expensive and not usable in the field. The conventional tests are much cheaper but take several days, thereby restricting diagnosis by physicians and laboratories. It is finding a balance between cheap, fast, and reliable that has led our project through development. In Dr. Akpaka’s own words: “such a device would enable the doctor to give a more accurate diagnosis.” In the end, point-of-care diagnostics are limited by their price and their sensitivity, both issues solved by our simple design and amplifying technique. </h2> | <h2> Dr. Akpaka informed us about the impact Salmonella and pathogenic E. Coli have on the communities on Trinidad, encasing our project as one of global impact. Current highest-class toxin identifiers take 30 minutes with the devices being expensive and not usable in the field. The conventional tests are much cheaper but take several days, thereby restricting diagnosis by physicians and laboratories. It is finding a balance between cheap, fast, and reliable that has led our project through development. In Dr. Akpaka’s own words: “such a device would enable the doctor to give a more accurate diagnosis.” In the end, point-of-care diagnostics are limited by their price and their sensitivity, both issues solved by our simple design and amplifying technique. </h2> | ||
</div> | </div> | ||
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<h2> <br> <br> <br> <br> <br> <font size="5.5"> Dr. Khalid Malik </font> </h2> | <h2> <br> <br> <br> <br> <br> <font size="5.5"> Dr. Khalid Malik </font> </h2> | ||
<h2> <i> <font size="3"> Consultant Physician | <h2> <i> <font size="3"> Consultant Physician | ||
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NYU Abu Dhabi Health and Wellness </font> </i> </h2> | NYU Abu Dhabi Health and Wellness </font> </i> </h2> | ||
<h4> “Currently, we have to wait 48-72 hours for targeted laboratory results of the patient’s blood and stool sample.” </h4> | <h4> “Currently, we have to wait 48-72 hours for targeted laboratory results of the patient’s blood and stool sample.” </h4> | ||
<h2> Dr. Khalid has stressed the important potential the device can contribute by making the diagnosis of food infections much faster, providing nearly immediate results compared to current solutions. This attribute provides the physician with more time and higher flexibility when trying to diagnose. The device can also make sure the patients themselves check their food as well as themselves for possible infections before having to consult a physician. Such opportunity becomes even more important, even life-saving, in communities with lower access to health professionals. </h2> | <h2> Dr. Khalid has stressed the important potential the device can contribute by making the diagnosis of food infections much faster, providing nearly immediate results compared to current solutions. This attribute provides the physician with more time and higher flexibility when trying to diagnose. The device can also make sure the patients themselves check their food as well as themselves for possible infections before having to consult a physician. Such opportunity becomes even more important, even life-saving, in communities with lower access to health professionals. </h2> | ||
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<h2> As food products are being imported into the UAE, they are being kept at airports and ports of entry until they are screened for bacterial pathogens which can takes more than 3 days. With this device, products can enter the market faster, and with food, the chance of it going to waste is severely decreased. It also makes it possible for routine inspections in grocery stores and restaurants to end in immediate response by the food inspector so that when the results are positive, the business can be closed for the public’s safety. The Agency has expressed full support of the project and suggests that accreditation of the device is possible for use in government regulation. </h2> | <h2> As food products are being imported into the UAE, they are being kept at airports and ports of entry until they are screened for bacterial pathogens which can takes more than 3 days. With this device, products can enter the market faster, and with food, the chance of it going to waste is severely decreased. It also makes it possible for routine inspections in grocery stores and restaurants to end in immediate response by the food inspector so that when the results are positive, the business can be closed for the public’s safety. The Agency has expressed full support of the project and suggests that accreditation of the device is possible for use in government regulation. </h2> | ||
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<h2> From her devotion in community outreach and involvement in projects related to global health back in India, Dr. Parekh stressed the paucity of potable, uncontaminated water in underdeveloped communities. Enormous number of young people, especially children under 5, suffer or die from dehydration due to consuming unclean water. To make an impact, Dr. Parekh highlighted the importance of instilling the mindset of valuing the safety of food and water through educational programs. She commented on how marketing strategies, such as the four Ps of marketing (product/place/price/promotion), can be utilized to aid cultivating the habit and promoting health and wellness in these communities. </h2> | <h2> From her devotion in community outreach and involvement in projects related to global health back in India, Dr. Parekh stressed the paucity of potable, uncontaminated water in underdeveloped communities. Enormous number of young people, especially children under 5, suffer or die from dehydration due to consuming unclean water. To make an impact, Dr. Parekh highlighted the importance of instilling the mindset of valuing the safety of food and water through educational programs. She commented on how marketing strategies, such as the four Ps of marketing (product/place/price/promotion), can be utilized to aid cultivating the habit and promoting health and wellness in these communities. </h2> | ||
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<h2> A challenge to implement this device in low-income countries would be the cost, drawing from a similar discussion on insect repellent bed nets (ITNs). The take-up could also be faced with other barriers in trying to make the device more affordable. For the US, the USDA (Department of Agriculture) can provide possible frameworks in ensuring food regulation through such a device. </h2> | <h2> A challenge to implement this device in low-income countries would be the cost, drawing from a similar discussion on insect repellent bed nets (ITNs). The take-up could also be faced with other barriers in trying to make the device more affordable. For the US, the USDA (Department of Agriculture) can provide possible frameworks in ensuring food regulation through such a device. </h2> | ||
</div> | </div> | ||
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<h2> The WHO stressed the recent outbreaks of Listeria in Hungary, and stressed the benefit our device would provide to Food Authorities and Public Health Institutions. The project directly touches upon the WHO principles as pointed out on their main web page. Prior to the use of the device for setting a standard in Food Health globally, authoritative licensing is required. </h2> | <h2> The WHO stressed the recent outbreaks of Listeria in Hungary, and stressed the benefit our device would provide to Food Authorities and Public Health Institutions. The project directly touches upon the WHO principles as pointed out on their main web page. Prior to the use of the device for setting a standard in Food Health globally, authoritative licensing is required. </h2> | ||
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<h2> <br> <br> <br> <br> <font size="5.5"> Institute for Public Health, Central Bosnia </font> </h2> | <h2> <br> <br> <br> <br> <font size="5.5"> Institute for Public Health, Central Bosnia </font> </h2> | ||
<h4> “The faster the result, the faster we can act. In intervening circumstances, such as in educational institutions, being able to prevent harm is vital.” </h4> | <h4> “The faster the result, the faster we can act. In intervening circumstances, such as in educational institutions, being able to prevent harm is vital.” </h4> | ||
− | + | <h2> The device would make life much easier for the food inspection patrol. Immediate action can be taken, on-the-ground, without waiting for several days to receive the result. This kind of action is needed in certain intervening circumstances, such as in educational institutions, and in massive public gatherings, where the scale of impact of an infection is severe. </h2> | |
+ | </div> | ||
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− | + | <a class="dropdown-item" href="https://2018.igem.org/Team:NYU_Abu_Dhabi/Results">Results</a> | |
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+ | <a class="dropdown-item" href="https://2018.igem.org/Team:NYU_Abu_Dhabi/Medal_Requirements">Medal Requirements</a> | ||
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+ | <a class="nav-link" href="https://2018.igem.org/Team:NYU_Abu_Dhabi/Hardware">Design<span class="sr-only"></span></a> | ||
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+ | Lab notebooks | ||
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+ | <a class="dropdown-item" href="https://2018.igem.org/Team:NYU_Abu_Dhabi/Ideation">Ideation</a> | ||
+ | <a class="dropdown-item" href="https://2018.igem.org/Team:NYU_Abu_Dhabi/Engineering">Engineering</a> | ||
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− | <a class="dropdown-item" href="https://2018.igem.org/Team:NYU_Abu_Dhabi/ | + | <a class="dropdown-item" href="https://2018.igem.org/Team:NYU_Abu_Dhabi/Public_Engagement">Education and Public Engagement</a> |
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<a class="dropdown-item" href="https://2018.igem.org/Team:NYU_Abu_Dhabi/Home_Outreach">Home Country Outreach</a> | <a class="dropdown-item" href="https://2018.igem.org/Team:NYU_Abu_Dhabi/Home_Outreach">Home Country Outreach</a> | ||
<a class="dropdown-item" href="https://2018.igem.org/Team:NYU_Abu_Dhabi/Social_Media">Social Media</a> | <a class="dropdown-item" href="https://2018.igem.org/Team:NYU_Abu_Dhabi/Social_Media">Social Media</a> | ||
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Latest revision as of 12:23, 9 November 2018
Integrated Human Practices
Our primary goal was to build a tool that enables users to check the safety of the food and water they might consume. We started off with the device as a wearable for travelers, who often fall victim to foodborne diseases. Extensive interviews, however, with possible users ranging from food vendors, travelers, pregnant women, to health professionals across 4 continents showed the device's wider potential contribution. The wearable then became a pen-and-holder to allow for this diverse usage while the casing color and material changed to accommodate various environments. Interactions with UAE and Bosnian government institutions prompted us to think about benefits to government and public agencies as well. The Quality Control Centre, Abu Dhabi Food Control Authority, and Institute of Public Health in Bosnia alongside food analysts indicated a niche in rapid food inspection and analysis that our device could fill upon refinement. Refinement meant integrating a faster DNA amplification technique operating at a lower temperature without sacrificing specificity. The device also had to be compact and safe to handle following discussions with health ethnologists and NGOs. The World Health Organization and our very own Vice Provost for Global Education made us realize the project as a start of a global health network. The device was designed in a way to be as neutral as possible to diverse cultural and social environments, with the idea of developing future plans for worldwide educational resources coupled with the distribution of the device. It has been clear to us that problems in global health cannot only be solved by using new biological and engineering integration but also social and educational progress. We are proud that Pathogene provides a new and unique guarantee for food safety on individual, communal, and governmental levels as a result of our integrated human practices. Please note that the interviews conducted with target groups have been IRB approved.
Expert Counsel