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Revision as of 12:32, 12 October 2018
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Integrated Human Practice
Our primary goal was to build a tool that enables users to check the safety of their food and water. We started off with the device as a wearable for travelers, who often fall victim to foodborne diseases. Extensive interviews, however, with possible users ranging from food vendors, travelers, pregnant women, to health professionals across 4 continents showed the device's wider potential contribution. The wearable then became a pen-and-holder to allow for this diverse usage while the casing color and material changed to accommodate various environments. Interactions with UAE and Bosnian government institutions prompted us to think about benefits to government and public agencies as well. The Quality Control Centre, Abu Dhabi Food Control Authority, and Institute of Public Health in Bosnia alongside food analysts indicated a niche in rapid food inspection and analysis that our device could fill upon refinement. Refinement meant integrating a faster DNA amplification technique operating at a lower temperature without sacrificing specificity. The device also had to be compact and safe to handle following discussions with health ethnologists and NGOs. The World Health Organization and our very own Vice Provost for Global Education made us realize the project as a start of a global health network. The device was designed in a way to be as neutral as possible to diverse cultural and social environments, with the idea of developing future plans for worldwide educational resources coupled with the distribution of the device. It has been clear to us that problems in global health cannot only be solved by using new biological and engineering integration but also social and educational progress. We are proud that Pathogene provides new and unique guarantee for food safety on individual/communal and governmental levels as a result of our integrated human practices.
Expert Counsel
Dr. Adnan Alatoom
Staff Physician and Head of the Pathology & Laboratory Medicine Institute
Cleveland Clinic Abu Dhabi
“Currently, the fastest clinical tools for pathogen detection take over 6 hours and cost 140$ per test.”
Clinical laboratories are at the center of the health providers’ analysis of food pathogens. Currently, the fastest tools they possess are PCR-based and take over 6 hours with per-sample price of over 100$. Less financially supported hospitals and healthcare providers might have to depend on machines that take several days. The more rapid the result is, the faster the response the clinical laboratory can provide to physicians and others. Bacterial pathogens of note in the region of Abu Dhabi are Campylobacter and Shigella. Devices used in the laboratory are provided for free by the manufacturers and they are recharged for the biological buffer and reagents.
Dr. Carol Brandt
Associate Vice Chancellor, Head of Global Education and Outreach, Vice Provost
NYU Abu Dhabi
“This device can create a global network of increasing food safety and contribute significantly to global health.”
The device could be a first step in creating an integrated network across the world, providing low-income communities not only with much higher food safety, but coupled with educational programs, providing them also with the skills they need to take it even further. Reaching out to local members of the community can make the device a household name and increase trust, not just in the device, but also in the NGOs working on the field. To this end, collaboration with already developed on-the-ground NGOs is a great window into integrating the device into the communities. Therefore, with centers around the world working on feedback and education of the device, it can make an even bigger contribution to global health.
Dr. Patrick E. Akpaka
Professor of Medical Microbiology
University of the West Indies, St. Augustine
“Conventional tests take 48 hours and cost 30-50$, being limited by series of tests needed after which the results are still not definitive.“
Dr. Akpaka informed us about the impact Salmonella and pathogenic E. Coli have on the communities on Trinidad, encasing our project as one of global impact. Current highest-class toxin identifiers take 30 minutes with the devices being expensive and not usable in the field. The conventional tests are much cheaper but take several days, thereby restricting diagnosis by physicians and laboratories. It is finding a balance between cheap, fast, and reliable that has led our project through development. In Dr. Akpaka’s own words: “such a device would enable the doctor to give a more accurate diagnosis.” In the end, point-of-care diagnostics are limited by their price and their sensitivity, both issues solved by our simple design and amplifying technique.
Dr. Khalid Malik
Consultant Physician NYU Abu Dhabi Health and Wellness
“Currently, we have to wait 48-72 hours for targeted laboratory results of the patient’s blood and stool sample.”
Dr. Khalid has stressed the important potential the device can contribute by making the diagnosis of food infections much faster, providing nearly immediate results compared to current solutions. This attribute provides the physician with more time and higher flexibility when trying to diagnose. The device can also make sure the patients themselves check their food as well as themselves for possible infections before having to consult a physician. Such opportunity becomes even more important, even life-saving, in communities with lower access to health professionals.
Abu Dhabi Food Safety Agency
“With a much faster response than 3 days, the device makes rapid and urgent response possible for the food inspector.”
As food products are being imported into the UAE, they are being kept at airports and ports of entry until they are screened for bacterial pathogens which can takes more than 3 days. With this device, products can enter the market faster, and with food, the chance of it going to waste is severely decreased. It also makes it possible for routine inspections in grocery stores and restaurants to end in immediate response by the food inspector so that when the results are positive, the business can be closed for the public’s safety. The Agency has expressed full support of the project and suggests that accreditation of the device is possible for use in government regulation.
Dr. Niyati Parekh
Director and Associate Professor of Public Health Nutrition
NYU College of Global Public Health
“Lots of children’s lives were lost yearly due to contacting water contaminated with food-related pathogens.”
From her devotion in community outreach and involvement in projects related to global health back in India, Dr. Parekh stressed the paucity of potable, uncontaminated water in underdeveloped communities. Enormous number of young people, especially children under 5, suffer or die from dehydration due to consuming unclean water. To make an impact, Dr. Parekh highlighted the importance of instilling the mindset of valuing the safety of food and water through educational programs. She commented on how marketing strategies, such as the four Ps of marketing (product/place/price/promotion), can be utilized to aid cultivating the habit and promoting health and wellness in these communities.
Dr. Diana Silver
Associate Professor of Public Health Policy and Management
NYU College of Global Public Health
“This device could contribute to the health of immuno-compromised individuals in the US, and to communities in low-income countries”
A challenge to implement this device in low-income countries would be the cost, drawing from a similar discussion on insect repellent bed nets (ITNs). The take-up could also be faced with other barriers in trying to make the device more affordable. For the US, the USDA (Department of Agriculture) can provide possible frameworks in ensuring food regulation through such a device.
Dr. Sanela Teskeredzic
Specialist and Head of Clinical Microbiology Laboratory
Hospital “Travnik”
“The high cost of DNA amplification devices limits the majority of hospitals and laboratories in providing the fastest and most accurate result possible.”
With the concept of the device as presented, it could significantly contribute to the work of most microbiological (clinical or sanitary) laboratories in the world. As we already use incubators, the eventual heating of the device for a faster result is not a problem. Using DNA rather than growing colonies not only increases the faithfulness of the result but decreases the time, effort, and danger of the traditional way of checking for these bacteria.
MSc Zudi Osmani
Head of the Department for Hygiene and Health Ecology
Institute for Public Health, SBK
“This device will allow inspectors to act immediately to contain food-related dangers, and not have to depend on several days old laboratory results. In that time, the food would have already been eaten.”
Accreditation will be the cornerstone of the fidelity of using such a device. The low cost of having such an accurate and fast way of detecting these pathogens is revolutionary for many areas of food inspection. Presently, devices that rely on similar DNA amplification methods are too expensive, and bulky, to significantly contribute to the improvement of food safety and sanitation in large parts of the world.
World Health Organization, Office in Bosnia and Herzegovina
“Food safety is an important component of any public health policy or measures to prevent diseases. Any region of the world can be affected where no or weak measure of food safety is implemented.”
The WHO stressed the recent outbreaks of Listeria in Hungary, and stressed the benefit our device would provide to Food Authorities and Public Health Institutions. The project directly touches upon the WHO principles as pointed out on their main web page. Prior to the use of the device for setting a standard in Food Health globally, authoritative licensing is required.
