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Revision as of 20:30, 17 October 2018
Project Description
PixCell
Electrogenetics is a synthetic biology discipline developing electronic methods to control and measure gene expression. For PixCell we developed the first aerobic electrogenetic control system.
Using this system we demonstrated electronic control of gene expression and built a affordable custom-built electrode array which can be used as a tool for precise, programmable biological patterning.
We further improved our system by building a library of electrogenetic parts compatible with a variety of assembly standards. This is the first electrogenetic toolkit and has been characterised for “plug-and-play” manipulation of the transcriptional response to electricity.
Robust models of the system were developed so that electrogenetic circuits can be tested in silico before they are in vivo.
Using this library we developed a device with an important application in the field of biocontainment.
Mechanism
Electronic control
Patterning