Our team seeks to synthesize membrane-less organelles and turn it into a multi-functional toolbox for synthetic biology based on basic phase separation principles, which is a rather fundamental field in condensed matter physics. Therefore, it’s not really a reality application so far. Nonetheless, it’s definitely not the reason that we are confined in the laboratory coping with experiments and mathematical models without making a difference to the society directly. Meanwhile, we need to get to know about the demand of engineers and consumers. Thus we did an integrated human practice in several different ways.
Inside the iGEM community, we made statistics of the education background and numbers of igemers each year in order to investigate how iGEM has been broadcasted internationally and how the field of synthetic biology has changed over the last 14 years. We noticed that most iGEM teams are becoming more and more diverse, which promotes the development of iGEM community but make it more challenging for team members to communicate. This can also be read as more people from different disciplines especially mathematics and physics have been devoted to systems and synthetic biology, which are interdisciplinary sciences needing various knowledge while on the same time, they can feed back to enrich the individual scientific disciplines and biology-based solutions for societal problems can be worked out.
We also tried to play an active part in public engagement. We communicated with people from various backgrounds in universities, high schools, kindergartens and on the internet. We realized that there has always been a gap between the achievements in scientific research and reality application. People from academic world and industrial world barely know each others’ requirements most of the time. Thus we discussed this topic in detail using fluorescence microscope as an example.
Our human practice reinforced our team construction creating more chance for the team members to communicate and collaborate with each other. We tried to make synthetic biology accessible for as many people as possible and we do expect our efforts may make a difference. Meanwhile, we’d be more than glad if our work may give the synthetic biology community some inspiration. To gain a deeper understanding of biology in the 21st century, we need to integrate knowledge from various disciplines while biology-based solutions to societal problems can influence the world more profoundly.
In the following sections, you will go through our human practice in details.
Investigation on the education background of iGEMers
Figure 1 shows the geographical distribution of the number of teams. (2007-2018)
Figure 2.A, B show teams attending iGEM from different regions. Figure 2.A shows the number of teams in each year (2007-2018) . Figure 2.B shows the proportion of each year (2007-2018). Different colors of columns represent different regions.
In 2007, only 61 teams from around the world participated in iGEM, but iGEM has now attracted more than 300 teams from around the world for three consecutive years(305 teams in 2016, 338 teams in 2017, 370 teams in 2018). Especially since 2015, IGEM has teams from Africa every year.
Overall, it could be found that the number of teams increases with the year. Though teams mainly come from Asia, North America and Europe, we still find more and more African and Latin American teams participating in this important event in the field of synthetic biology. We have reason to believe that the influence of iGEM in developing countries is gradually increasing.
In addition, we find that iGEM's influence in Asia, especially in the Western Pacific, is gradually increasing. Asia has become an important pillar in iGEM that cannot be ignored.
Figure 3.A.B show the proportion of track selections in 10 years. Figure3.A shows the proportion in 2009-2013 and Figure3.B in 2014-2018. Different colors of columns represent different tracks.
In the 2009-2013 track selection, ‘Foundational Research’ entered the Top 3 tracks that were most popular in the past five times, followed by ‘Enviroment’ 4 times, ‘Health’ 3 times, and ‘New application’ 3 times.
In 2014, iGEM officially made major adjustments to the track. Added the resources of ‘Community labs’, ‘Hardware’, ‘Measurement’, ‘Microfluids’, ‘Arts & Design’, and split the original ‘Food & Energy’ into ‘Energy’, ‘Food & Nutrition’ (2014);and split ‘Health’ into ‘Diagnostics’, ‘Therapeutics’ in 2016. After the adjustment, if we do not count ‘High school’ as a scientific research track, then the Top 3 list is as shown in the table below.
Table 1 shows the top three tracks that are most popular among the participating teams in 10 years.
We find that in 2009-2018, iGEM's participating teams are more concerned with the four aspects of Environment, Foundational Research, Health & Medicine, and New application. This implies that environmental pollution and health care are still the most popular issues in the world.
It is worth noting that compared with 2009, the choice of track in 2018 is more diversified, and the track of ‘Art & Design’ and other humanities and social sciences has received enough attention.
In 2014, iGEM officially made major adjustments to the track. Added the resources of ‘Community labs’, ‘Hardware’, ‘Measurement’, ‘Microfluids’, ‘Arts & Design’, and split the original ‘Food & Energy’ into ‘Energy’, ‘Food & Nutrition’ (2014);and split ‘Health’ into ‘Diagnostics’, ‘Therapeutics’ in 2016. After the adjustment, if we do not count ‘High school’ as a scientific research track, then the Top 3 list is as shown in the table below.
In 2014, iGEM officially made major adjustments to the track. Added the resources of ‘Community labs’, ‘Hardware’, ‘Measurement’, ‘Microfluids’, ‘Arts & Design’, and split the original ‘Food & Energy’ into ‘Energy’, ‘Food & Nutrition’ (2014);and split ‘Health’ into ‘Diagnostics’, ‘Therapeutics’ in 2016. After the adjustment, if we do not count ‘High school’ as a scientific research track, then the Top 3 list is as shown in the table below.
In 2014, iGEM officially made major adjustments to the track. Added the resources of ‘Community labs’, ‘Hardware’, ‘Measurement’, ‘Microfluids’, ‘Arts & Design’, and split the original ‘Food & Energy’ into ‘Energy’, ‘Food & Nutrition’ (2014);and split ‘Health’ into ‘Diagnostics’, ‘Therapeutics’ in 2016. After the adjustment, if we do not count ‘High school’ as a scientific research track, then the Top 3 list is as shown in the table below.
In 2014, iGEM officially made major adjustments to the track. Added the resources of ‘Community labs’, ‘Hardware’, ‘Measurement’, ‘Microfluids’, ‘Arts & Design’, and split the original ‘Food & Energy’ into ‘Energy’, ‘Food & Nutrition’ (2014);and split ‘Health’ into ‘Diagnostics’, ‘Therapeutics’ in 2016. After the adjustment, if we do not count ‘High school’ as a scientific research track, then the Top 3 list is as shown in the table below.
In 2014, iGEM officially made major adjustments to the track. Added the resources of ‘Community labs’, ‘Hardware’, ‘Measurement’, ‘Microfluids’, ‘Arts & Design’, and split the original ‘Food & Energy’ into ‘Energy’, ‘Food & Nutrition’ (2014);and split ‘Health’ into ‘Diagnostics’, ‘Therapeutics’ in 2016. After the adjustment, if we do not count ‘High school’ as a scientific research track, then the Top 3 list is as shown in the table below.
In 2014, iGEM officially made major adjustments to the track. Added the resources of ‘Community labs’, ‘Hardware’, ‘Measurement’, ‘Microfluids’, ‘Arts & Design’, and split the original ‘Food & Energy’ into ‘Energy’, ‘Food & Nutrition’ (2014);and split ‘Health’ into ‘Diagnostics’, ‘Therapeutics’ in 2016. After the adjustment, if we do not count ‘High school’ as a scientific research track, then the Top 3 list is as shown in the table below.
In the following sections, you will go through our human practice in details.