Line 190: | Line 190: | ||
</tr> | </tr> | ||
<tr> | <tr> | ||
− | <th>R<sup>2</sup> value<th> | + | <th>R<sup>2</sup> value</th> |
<td>0.908</td> | <td>0.908</td> | ||
<td>0.997</td> | <td>0.997</td> | ||
Line 212: | Line 212: | ||
The negative correlation was revealed by Pearson correlation coefficient R and coefficient of determination R<sup>2</sup>. | The negative correlation was revealed by Pearson correlation coefficient R and coefficient of determination R<sup>2</sup>. | ||
</article> | </article> | ||
− | <table id="t01" class="centern" style="margin-top:30px; margin-bottom:30px;" width="100 | + | <table id="t01" class="centern" style="margin-top:30px; margin-bottom:30px;" width="100"> |
<caption style="line-height:1.5; text.align:left;"><b>Table 2:</b>R and R<sup>2</sup> values of the tested constructs.</caption> | <caption style="line-height:1.5; text.align:left;"><b>Table 2:</b>R and R<sup>2</sup> values of the tested constructs.</caption> | ||
<tr> | <tr> |
Revision as of 17:53, 17 October 2018
Toxicity Results
Abstract
Evaluation
Heavy metal exposure poses many risks and dangers to living organisms and the environment. Certain heavy metal ions such as copper can interact with enzymes and lower their activity as well as their specificity. Reactive oxygen species (ROS) arise from processes such as Fenton chemistry and Haber-Weiss reactions. Therefore, a sophisticated approach to lower the toxic effects of heavy metals on the cell is desired. We evaluated several approaches of applying anti-oxidants against the generation of ROS.
In our project, we set a focus on the accumulation of copper ions. Furthermore, using cupric salts is cheaper than gold ions and easier to solve than ferric salts. Its toxicity is lower than that of silver ions. Hence there is a broader spectrum in which anti-toxic measures can be explored. Therefore, we tested our approaches on anti-oxidant measures in different concentrations of cupric salts.
Subject to our research were the five following composite parts: BBa_K2638109, BBa_K2638112, BBa_K2638114, BBa_K2638110 and BBa_K2638118.
BBa_K2638112 | pSB1C3 | BBa_K2638114 | BBa_K2638118 | BBa_K2638110 | |
---|---|---|---|---|---|
R value | 0.996 | 0.952 | 0.993 | 0.987 | 0.994 |
R2 value | 0.992 | 0.907 | 0.985 | 0.973 | 0.989 |
BBa_K2638112 | pSB1C3 | BBa_K2638114 | BBa_K2638118 | BBa_K2638110 | |
---|---|---|---|---|---|
R value | 0.953 | 0.998 | 0.968 | 0.972 | 0.915 |
R2 value | 0.908 | 0.997 | 0.937 | 0.945 | 0.837 |
BBa_K2638112 | pSB1C3 | BBa_K2638114 | BBa_K2638118 | BBa_K2638110 | |
---|---|---|---|---|---|
R value | -0.576 | -0.955 | -0.817 | -0.952 | -0.924 |
R2 value | 0.332 | 0.913 | 0.668 | 0.906 | 0.853 |