Difference between revisions of "Team:CPU CHINA"

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<script src="https://2017.igem.org/Team:CPU_CHINA/js/bootstrap?action=raw&amp;ctype=text/javascript"></script>
 
<script src="https://2017.igem.org/Team:CPU_CHINA/js/bootstrap?action=raw&amp;ctype=text/javascript"></script>
 
<link rel="stylesheet" href="https://2018.igem.org/Team:CPU_CHINA/bootstrap_style_css?action=raw&ctype=text/css">
 
<link rel="stylesheet" href="https://2018.igem.org/Team:CPU_CHINA/bootstrap_style_css?action=raw&ctype=text/css">
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<link rel="stylesheet" href="https://2018.igem.org/Team:CPU_CHINA/navfoot_style_css?action=raw&amp;ctype=text/css">
 
 
</head>
 
</head>
 
<style>
 
<style>
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{
 
{
 
position:relative;
 
position:relative;
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top:-20px;
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top:-60px;
 
}
 
}
 
button
 
button
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outline:none;
 
outline:none;
 
}
 
}
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#top_title{
 
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    display:none !important;
 
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}
 
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#sideMenu{
 
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    display:none !important;
 
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}
 
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.img-div p{
 
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    margin: 10px 0 40px 0;
 
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    font-size: 20px !important;
 
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    text-align: center !important;
 
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    font-family: "Century Gothic";
 
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}
 
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.homej:link{
 
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color:rgb(189,190,176);text-decoration:none;
 
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}
 
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.homej:hover{
 
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color:rgb(0,0,0);
 
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}
 
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.homej:visited{
 
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color:rgb(189,190,176);text-decoration:none;
 
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}
 
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button:hover{background-color:#400080;}
 
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a:visited{color:purple;}
 
 
.mw-content-ltr {
 
.mw-content-ltr {
 
     background: url(https://static.igem.org/mediawiki/2018/b/bc/T--CPU_CHINA--wiki-background.png) center 29px;position:relative;
 
     background: url(https://static.igem.org/mediawiki/2018/b/bc/T--CPU_CHINA--wiki-background.png) center 29px;position:relative;
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}
 
}
  
 +
.btn-group{
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border:none;
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background-color:transparent;
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height:45px;
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position:absolute;
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float:right;
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top: 9%;
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}
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 +
.head_btn{
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width:100%;
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height:45px;
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.box{
 
.box{
 
       position: absolute;
 
       position: absolute;
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<!--*******************************************头部代码***************************************-->
 
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<div class="btn-group"style="border:none;background-color:transparent;width: 80px;height:45px;position:relative;top: 60px;left: 15%;">
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<div class="btn-group"style="width:70px;left: 16%;">
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                <button id="home"type="button" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false" style="border:none;background-color:transparent;width: 100%;height:45px;" onclick="returnHome()"></button>
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<button id="home"type="button" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false"class="head_btn" onclick="returnHome()"></button>
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</div>
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</div>
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<script>
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<script>
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function returnHome(){
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function returnHome(){
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  window.location.href="https://2018.igem.org/Team:CPU_CHINA"
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  window.location.href="https://2018.igem.org/Team:CPU_CHINA"
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}
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}
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</script>
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</script>
−
 
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<div class="btn-group"  style="border:none;background-color:transparent;width: 100px;height:45px;position:relative;float:right;top: 60px;left: -70%;">
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                <button type="button" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false" style="border:none;background-color:transparent;width: 100%;height:45px;">
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                </button>
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                <ul class="dropdown-menu" style="background:url(https://static.igem.org/mediawiki/2018/d/d3/T--CPU_CHINA--dropdown1.png)">
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                    <li style="margin-top:23px">  </li>
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                    <li>
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−
                        <a href="https://2018.igem.org/Team:CPU_CHINA/Background">Background</a>
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                    </li>
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−
                    <li>
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−
                        <a href="https://2018.igem.org/Team:CPU_CHINA/Results">Results</a>
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                    </li>
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−
                    <li>
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−
                        <a href="https://2018.igem.org/Team:CPU_CHINA/Experiments">Experiments</a>
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                    </li>
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−
                    <li>
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−
                        <a href="https://2018.igem.org/Team:CPU_CHINA/Application">Application</a>
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                    </li>
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−
                    <li>
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−
                        <a href="https://2018.igem.org/Team:CPU_CHINA/Part">Part</a>
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                    </li>
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−
                    <li>
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−
                        <a href="https://2018.igem.org/Team:CPU_CHINA/Interlab">Interlab</a>
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                    </li>
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−
                </ul>
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−
</div>
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−
 
+
  
−
            <div class="btn-group"  style="border:none;background-color:transparent;width: 190px;height:45px;position:relative;float:right;top: 60px;left: -48%;">
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<div class="btn-group"  style=" width: 100px; left: 23%;">
−
                <button type="button" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false"style="border:none;background-color:transparent;width:100%;height:45px;">
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<button type="button" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false" class="head_btn"></button>
−
                </button>
+
<ul class="dropdown-menu" style="background:url(https://static.igem.org/mediawiki/2018/d/d3/T--CPU_CHINA--dropdown1.png)">
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                <ul class="dropdown-menu" style="background:url(https://static.igem.org/mediawiki/2018/4/4a/T--CPU_CHINA--dropdown2.png)">
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<li style="margin-top:23px">  </li>
−
                    <li style="margin-top:23px">  </li>
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<li>
−
                    <li>
+
<a href="https://2018.igem.org/Team:CPU_CHINA/Background">Background</a>
−
                        <a href="https://2018.igem.org/Team:CPU_CHINA/HP/Silver">Silver HP</a>
+
</li>
−
                    </li>
+
<li>
−
                    <li>
+
<a href="https://2018.igem.org/Team:CPU_CHINA/Results">Results</a>
−
                        <a href="https://2018.igem.org/Team:CPU_CHINA/HP/Gold_Integrated">Intergrated and Gold HP</a>
+
</li>
−
                    </li>
+
<li>
−
                    <li>
+
<a href="https://2018.igem.org/Team:CPU_CHINA/Experiments">Experiments</a>
−
                        <a href="https://2018.igem.org/Team:CPU_CHINA/Engagement">Education and Public Engagement</a>
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</li>
−
                    </li>
+
<li>
−
                </ul>
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<a href="https://2018.igem.org/Team:CPU_CHINA/Application">Application</a>
−
            </div>
+
</li>
 +
<li>
 +
<a href="https://2018.igem.org/Team:CPU_CHINA/Part">Part</a>
 +
</li>
 +
<li>
 +
<a href="https://2018.igem.org/Team:CPU_CHINA/Interlab">Interlab</a>
 +
</li>
 +
</ul>
 +
</div>
 +
<div class="btn-group"  style=" width: 190px;left: 32%;">
 +
        <button type="button" class="head_btn" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false">
 +
        </button>
 +
        <ul class="dropdown-menu" style="background:url(https://static.igem.org/mediawiki/2018/4/4a/T--CPU_CHINA--dropdown2.png)">
 +
            <li style="margin-top:23px">  </li>
 +
            <li>
 +
            <a href="https://2018.igem.org/Team:CPU_CHINA/HP/Silver">Silver HP</a>
 +
            </li>
 +
            <li>
 +
            <a href="https://2018.igem.org/Team:CPU_CHINA/HP/Gold_Integrated">Intergrated and Gold HP</a>
 +
            </li>
 +
            <li>
 +
            <a href="https://2018.igem.org/Team:CPU_CHINA/Engagement">Education and Public Engagement</a>
 +
            </li>
 +
        </ul>
 +
    </div>
  
  
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            <div class="btn-group"  style="border:none;background-color:transparent;width: 105px;height:45px;position:relative;float:right;top: 60px;left: -16%;">
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    <div class="btn-group"  style=" width: 105px; left: 55%;">
−
              <button type="button" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false"style="border:none;background-color:transparent;width:100%;height:45px;"></button>
+
        <button type="button" class="head_btn" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false"></button>
−
             
+
    </div>
−
            </div>
+
  
−
            <div class="btn-group" style="border:none;background-color:transparent;width: 105px;height:45px;position:relative;float:right;top: 60px;left: 3%;">
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    <div class="btn-group" style=" width: 105px; left: 65%;">
−
                <button type="button" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false" style="border:none;background-color:transparent;width:100%;height:45px;"></button>
+
        <button type="button" class="head_btn" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false"></button>
−
                <ul class="dropdown-menu" style="background:url(https://static.igem.org/mediawiki/2018/a/a5/T--CPU_CHINA--dropdown3.png)">
+
        <ul class="dropdown-menu" style="background:url(https://static.igem.org/mediawiki/2018/a/a5/T--CPU_CHINA--dropdown3.png)">
−
                    <li style="margin-top:23px">  </li>
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<li style="margin-top:23px">  </li>
−
                    <li>
+
<li>
−
                        <a href="https://2018.igem.org/Team:CPU_CHINA/Notebook/Log">Log</a>
+
<a href="https://2018.igem.org/Team:CPU_CHINA/Notebook/Log">Log</a>
−
                    </li>
+
</li>
−
                    <li>
+
<li>
−
                        <a href="https://2018.igem.org/Team:CPU_CHINA/Safety">Safety</a>
+
<a href="https://2018.igem.org/Team:CPU_CHINA/Safety">Safety</a>
−
                    </li>
+
</li>
−
            </div>
+
</ul>
 +
    </div>
  
−
            <div class="btn-group" style="border:none;background-color:transparent;width: 95px;height:45px;position:relative;float:right;top: 60px;left: 20%;">
+
    <div class="btn-group" style=" width: 95px; left: 75%;">
−
                <button type="button" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false" style="border:none;background-color:transparent;width:100%;height:45px;"></button>
+
        <button type="button" class="head_btn" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false"></button>
−
                <ul class="dropdown-menu" style="background:url(https://static.igem.org/mediawiki/2018/c/c5/T--CPU_CHINA--dropdown4.png)">
+
        <ul class="dropdown-menu" style="background:url(https://static.igem.org/mediawiki/2018/c/c5/T--CPU_CHINA--dropdown4.png)">
−
                    <li style="margin-top:23px">  </li>
+
<li style="margin-top:23px">  </li>
−
                    <li>
+
<li>
−
                        <a href="https://2018.igem.org/Team:CPU_CHINA/Team">Team</a>
+
<a href="https://2018.igem.org/Team:CPU_CHINA/Team">Team</a>
−
                    </li>
+
</li>
−
                    <li>
+
<li>
−
                        <a href="https://2018.igem.org/Team:CPU_CHINA/Attributions">Attributions</a>
+
<a href="https://2018.igem.org/Team:CPU_CHINA/Attributions">Attributions</a>
−
                    </li>
+
</li>
−
                    <li>
+
<li>
−
                        <a href="https://2018.igem.org/Team:CPU_CHINA/Collborations">Collaborations</a>
+
<a href="https://2018.igem.org/Team:CPU_CHINA/Collborations">Collaborations</a>
−
                    </li>
+
</li>
−
            </div>
+
</ul>
 +
    </div>
  
  
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<div style="position:relative;top:280px;font-size:16px;color:black;" id="href">
 
<div style="position:relative;top:280px;font-size:16px;color:black;" id="href">
 
More relevant background information can be seen in <a href="/Team:CPU_CHINA/Background">Background</a>
 
More relevant background information can be seen in <a href="/Team:CPU_CHINA/Background">Background</a>
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<div>
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</div>
  
 
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</div>
 
</div>
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</body>
 
</body>

Revision as of 14:55, 7 September 2018

Hepatocellular carcinoma (HCC), also called malignant hepatoma, is one of the deadliest cancers. Through the introduction of a double-stranded RNA to the targeted messenger RNA (mRNA), RNA interference (RNAi) leads to the specific cleavage of the mRNA and efficient silencing of gene expression. Since RNAi could be used to silence genes involved in the development and progression of carcinomas, it has promising therapeutic potential for their treatment. The gene therapy strategy we propose here: (1) utilize two cancer-specific promoters (one HCC-specific) to open an AND-gated system to target HCC, the selectivity supposed to be extremely high; (2) is dependent on and hence controllable by a low molecular weight compound; (3) has the flexibility to be adapted to target any mRNA and, if there are disease-specific promoters, other diseases.
More relevant background information can be seen in Background