Difference between revisions of "Team:IIT Delhi/Description"
(Prototype team page) |
|||
| Line 7: | Line 7: | ||
<h1>Description</h1> | <h1>Description</h1> | ||
| − | <p> | + | <p>With the growth of synthetic biology, there has been an increase in the development of digital synthetic circuits. They require biological logic gates that can accept a binary input and generates a suitable output. But biological systems may not always exist at two stable concentrations. Hence there exists a need of robust and reliable circuits that can transform the analog and stochastic behaviours of biology into a digital response. Our elementary constructs can then be used to develop complex circuits with specialized functions. <br> |
| + | <br> | ||
| + | Recombinases are enzymes that have proven to be highly robust and efficient. They trigger site-specific recombination to perform excision/incision or inversion of genetic circuits, exclusively or in tandem to produce the desired gene expression. Our project involves use of serine based recombinases to develop a novel recombinase based toolkit of elementary circuits such as switch, feedforward loop, feedback loop etc. This toolkit will allow researchers to develop modular and orthogonal systems that can be tuned provide the desired output.</p> | ||
</div> | </div> | ||
Revision as of 17:23, 29 June 2018
Description
With the growth of synthetic biology, there has been an increase in the development of digital synthetic circuits. They require biological logic gates that can accept a binary input and generates a suitable output. But biological systems may not always exist at two stable concentrations. Hence there exists a need of robust and reliable circuits that can transform the analog and stochastic behaviours of biology into a digital response. Our elementary constructs can then be used to develop complex circuits with specialized functions.
Recombinases are enzymes that have proven to be highly robust and efficient. They trigger site-specific recombination to perform excision/incision or inversion of genetic circuits, exclusively or in tandem to produce the desired gene expression. Our project involves use of serine based recombinases to develop a novel recombinase based toolkit of elementary circuits such as switch, feedforward loop, feedback loop etc. This toolkit will allow researchers to develop modular and orthogonal systems that can be tuned provide the desired output.
What should this page contain?
- A clear and concise description of your project.
- A detailed explanation of why your team chose to work on this particular project.
- References and sources to document your research.
- Use illustrations and other visual resources to explain your project.
Inspiration
See how other teams have described and presented their projects:
Advice on writing your Project Description
We encourage you to put up a lot of information and content on your wiki, but we also encourage you to include summaries as much as possible. If you think of the sections in your project description as the sections in a publication, you should try to be concise, accurate, and unambiguous in your achievements.
References
iGEM teams are encouraged to record references you use during the course of your research. They should be posted somewhere on your wiki so that judges and other visitors can see how you thought about your project and what works inspired you.