Difference between revisions of "Team:Queens Canada/Hardware"

 
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<h3>★  ALERT! </h3>
 
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<p>This page is used by the judges to evaluate your team for the <a href="https://2018.igem.org/Judging/Medals">medal criterion</a> or <a href="https://2018.igem.org/Judging/Awards"> award listed below</a>. </p>
 
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<p> Delete this box in order to be evaluated for this medal criterion and/or award. See more information at <a href="https://2018.igem.org/Judging/Pages_for_Awards"> Instructions for Pages for awards</a>.</p>
 
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<h2 style="width:70%;margin-left:15%">Hardware</h2>
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<h3 style="width:70%;margin-left:15%">Overview</h3>
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<p style="width:70%;margin-left:15%;font-size:18px">Saliva contains a wealth of information about one’s health. In the doctor’s office, saliva samples are readily taken to screen for disease as well as measure hormone and other bioactive molecule presence. This year, team Queen’s Canada has developed a diagnostic pacifier with the ability to passively collect saliva, measure analytes present, and wirelessly transmit this data. The pacifier works by passively collecting saliva from the user's mouth into the pacifier’s internal compartment through a channel in the nipple. An off-board system could collect the saliva and mix it with the <a href="https://2018.igem.org/Team:Queens_Canada/Design" target="_blank"> FRET biosensor</a>, then its composition could be probed with a fluorometer, or confocal microscope. The onboard sytem would contain contain an <a href="https://2018.igem.org/Team:Queens_Canada/Design" target="_blank">immobilized protein biosensor.</a> Once enough saliva has accumulated within the well type container, the proteins would react and produce a luminescent signal corresponding to analyte concentration. This luminescence would be detected by the built-in luminometer located directly behind the well which would transfer the information to the user device. Some of our considerations and investigations during our design process are summarized below.</p>
  
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<a href="https://2018.igem.org/Team:Queens_Canada/Pacifier"><h3 style="width:70%;margin-left:15%;color:blue; text-decoration: underline">Pacifier</h3></a>
  
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<a href="https://2018.igem.org/Team:Queens_Canada/Luminometer"><h3 style="width:70%;margin-left:15%;color:blue; text-decoration: underline">Luminometer</h3></a>
  
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<a href="https://2018.igem.org/Team:Queens_Canada/Thermistor"><h3 style="width:70%;margin-left:15%; color:blue; text-decoration: underline">Thermistor</h3></a>
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<h1>Hardware</h1>
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<p style="width:70%;margin-left:15%;font-size:18px">Below are photos of the finished pacifier, with the luminometer installed within in.</p>
  
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<a href="https://2018.igem.org/Team:Queens_Canada/Pacifier"><img src="https://static.igem.org/mediawiki/2018/f/fe/T--Queens_Canada--pac1.jpeg" alt='bestfit' width="50%"/></a>
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<a href="https://2018.igem.org/Team:Queens_Canada/Pacifier"><img style="float:left" src="https://static.igem.org/mediawiki/2018/6/65/T--Queens_Canada--pac2.jpeg" alt='bestfit' width="50%"/></a>
 
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<a href="https://2018.igem.org/Team:Queens_Canada/Pacifier"><img src="https://static.igem.org/mediawiki/2018/a/a4/T--Queens_Canada--pac3.jpeg" alt='bestfit' width="49%"/></a>
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<h3>Best Hardware Special Prize</h3>
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<a href="https://2018.igem.org/Team:Queens_Canada/Pacifier"><img style="float:left" src="https://static.igem.org/mediawiki/2018/0/0d/T--Queens_Canada--pac4.jpeg" alt='bestfit' width="50%"/></a>
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<p>iGEM is about making teams of students making synthetic biology projects. We encourage teams to work with parts and build biological devices in the lab. But we are inclusive and want all teams to work on many other types of problems in synbio. Robotic assembly, microfluidics, low cost equipment and measurement hardware are all areas ripe for innovation in synbio. </p>
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<p>
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Teams who are interested in working with hardware as a side project are encouraged to apply for the hardware award.
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<br><br>
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To compete for the <a href="https://2018.igem.org/Judging/Awards">Best Hardware prize</a>, please describe your work on this page and also fill out the description on the <a href="https://2018.igem.org/Judging/Judging_Form">judging form</a>.
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You must also delete the message box on the top of this page to be eligible for this prize.
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<h3>Inspiration</h3>
 
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<p>You can look at what other teams did to get some inspiration! <br />
 
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Here are a few examples:</p>
 
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<ul>
 
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<li><a href="https://2016.igem.org/Team:Valencia_UPV">2016 Valencia UPV</a></li>
 
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<li><a href="https://2016.igem.org/Team:Aachen">2016 Aachen </a></li>
 
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<li><a href="https://2015.igem.org/Team:TU_Delft">2015 TU Delft  </a></li>
 
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<li><a href="https://2015.igem.org/Team:TU_Darmstadt">2015 TU Darmstadt</a></li>
 
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Latest revision as of 19:20, 17 October 2018

Hardware

Overview

Saliva contains a wealth of information about one’s health. In the doctor’s office, saliva samples are readily taken to screen for disease as well as measure hormone and other bioactive molecule presence. This year, team Queen’s Canada has developed a diagnostic pacifier with the ability to passively collect saliva, measure analytes present, and wirelessly transmit this data. The pacifier works by passively collecting saliva from the user's mouth into the pacifier’s internal compartment through a channel in the nipple. An off-board system could collect the saliva and mix it with the FRET biosensor, then its composition could be probed with a fluorometer, or confocal microscope. The onboard sytem would contain contain an immobilized protein biosensor. Once enough saliva has accumulated within the well type container, the proteins would react and produce a luminescent signal corresponding to analyte concentration. This luminescence would be detected by the built-in luminometer located directly behind the well which would transfer the information to the user device. Some of our considerations and investigations during our design process are summarized below.

Pacifier

Luminometer

Thermistor

Below are photos of the finished pacifier, with the luminometer installed within in.

bestfit bestfit
bestfit bestfit