ElishaKrauss (Talk | contribs) (Undo revision 485983 by ElishaKrauss (talk)) |
|||
(178 intermediate revisions by 4 users not shown) | |||
Line 2: | Line 2: | ||
{{Queens Canada/Navbar}} | {{Queens Canada/Navbar}} | ||
<html> | <html> | ||
− | < | + | <head> |
<style> | <style> | ||
* { | * { | ||
Line 8: | Line 8: | ||
} | } | ||
− | /* | + | |
+ | |||
+ | /* Create two equal columns that floats next to each other */ | ||
+ | .column { | ||
+ | float: left; | ||
+ | width: 50%; | ||
+ | padding: 10px; | ||
+ | height: 300px; /* Should be removed. Only for demonstration */ | ||
+ | } | ||
+ | |||
+ | /* Clear floats after the columns */ | ||
+ | .row:after { | ||
+ | content: ""; | ||
+ | display: table; | ||
+ | clear: both; | ||
+ | } | ||
+ | |||
body { | body { | ||
− | + | background-color: white; | |
− | + | position: relative; | |
+ | margin-left: auto; | ||
+ | margin-right: auto; | ||
} | } | ||
/* The actual timeline (the vertical ruler) */ | /* The actual timeline (the vertical ruler) */ | ||
.timeline { | .timeline { | ||
− | + | position: relative; | |
− | + | max-width: 70%; | |
− | + | margin: 0 auto; | |
} | } | ||
/* The actual timeline (the vertical ruler) */ | /* The actual timeline (the vertical ruler) */ | ||
.timeline::after { | .timeline::after { | ||
− | + | content: ''; | |
− | + | position: absolute; | |
− | + | width: 6px; | |
− | + | background-color: #0485BF; | |
− | + | top: 0; | |
− | + | bottom: 0; | |
− | + | left: 50%; | |
− | + | margin-left: -3px; | |
+ | z-index: -1; | ||
} | } | ||
/* Container around content */ | /* Container around content */ | ||
.container { | .container { | ||
− | + | padding: 10px 40px; | |
− | + | position: relative; | |
− | + | background-color: inhert; | |
− | + | width: 50%; | |
} | } | ||
/* The circles on the timeline */ | /* The circles on the timeline */ | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
/* Place the container to the left */ | /* Place the container to the left */ | ||
.left { | .left { | ||
− | + | left: -25%; | |
} | } | ||
/* Place the container to the right */ | /* Place the container to the right */ | ||
.right { | .right { | ||
− | + | left: 25%; | |
} | } | ||
/* Add arrows to the left container (pointing right) */ | /* Add arrows to the left container (pointing right) */ | ||
.left::before { | .left::before { | ||
− | + | content: " "; | |
− | + | height: 0; | |
− | + | position: absolute; | |
− | + | top: 22px; | |
− | + | width: 0; | |
− | + | z-index: 1; | |
− | + | right: 30px; | |
− | + | border: medium solid white; | |
− | + | border-width: 10px 0 10px 10px; | |
− | + | border-color: transparent transparent transparent #0485BF; | |
} | } | ||
/* Add arrows to the right container (pointing left) */ | /* Add arrows to the right container (pointing left) */ | ||
.right::before { | .right::before { | ||
− | + | content: " "; | |
− | + | height: 0; | |
− | + | position: absolute; | |
− | + | top: 22px; | |
− | + | width: 0; | |
− | + | z-index: 1; | |
− | + | left: 30px; | |
− | + | border: medium solid white; | |
− | + | border-width: 10px 10px 10px 0; | |
− | + | border-color: transparent #0485BF transparent transparent; | |
} | } | ||
/* Fix the circle for containers on the right side */ | /* Fix the circle for containers on the right side */ | ||
.right::after { | .right::after { | ||
− | + | left: -15px; | |
} | } | ||
/* The actual content */ | /* The actual content */ | ||
.content { | .content { | ||
− | + | padding: 20px 30px; | |
− | + | position: relative;border: 20px double #0485BF; | |
− | + | border-radius: 15px; | |
− | + | ||
} | } | ||
+ | |||
+ | .box { | ||
+ | padding: 15px 15px; | ||
+ | background-color: #FFFFFF; | ||
+ | position: relative;border: 20px double #0485BF; | ||
+ | border-radius: 50px; | ||
+ | display: block; | ||
+ | margin-left: auto; | ||
+ | margin-right: auto; | ||
+ | width: 80%; | ||
+ | } | ||
+ | |||
+ | /* Media queries - Responsive timeline on screens less than 600px wide */ | ||
+ | @media screen and (max-width: 600px) { | ||
+ | /* Place the timelime to the left */ | ||
+ | .timeline::after { | ||
+ | left: 31px; | ||
+ | } | ||
− | /* Full-width containers */ | + | /* Full-width containers */ |
.container { | .container { | ||
width: 100%; | width: 100%; | ||
Line 112: | Line 137: | ||
padding-right: 25px; | padding-right: 25px; | ||
} | } | ||
− | + | ||
− | /* Make sure that all arrows are pointing leftwards */ | + | /* Make sure that all arrows are pointing leftwards */ |
.container::before { | .container::before { | ||
left: 60px; | left: 60px; | ||
Line 121: | Line 146: | ||
} | } | ||
− | /* Make sure all circles are at the same spot */ | + | /* Make sure all circles are at the same spot */ |
.left::after, .right::after { | .left::after, .right::after { | ||
− | left: | + | left: 0px; |
} | } | ||
− | + | ||
− | /* Make all right containers behave like the left ones */ | + | /* Make all right containers behave like the left ones */ |
.right { | .right { | ||
left: 0%; | left: 0%; | ||
} | } | ||
+ | } | ||
+ | |||
+ | h5 { | ||
+ | text-align: center; | ||
+ | } | ||
+ | |||
+ | h3 { | ||
+ | text-align: center; | ||
} | } | ||
</style> | </style> | ||
Line 136: | Line 169: | ||
<body> | <body> | ||
− | <div class="timeline"> | + | <h2 style="width:70%;margin-left:15%">Market Direction Analysis</h2> |
− | + | <br> | |
− | + | <p style="width:1200px;margin-left:12%;font-size: 18pt"> <br><br> | |
− | + | <img src="https://static.igem.org/mediawiki/2018/b/bb/T--Queens_Canada--marketstrategy.png" alt='wirelessLum' style="height=50%"/><br><br> | |
− | < | + | Following our interview series, we reflected on all the insight we had gained from the various experts, parents, and community members. We came to the conclusion, that the use of the diagnostic pacifier device, was perhaps not best fit in the hands of all parents, because they may lack the scientific literacy to properly interpret fluctuations in their child's hormone levels. Additionally we received specific feedback on our pacifiers design and implemented the experts advice into our next iteration of the design seen <a href="https://2018.igem.org/Team:Queens_Canada/Pacifier">here.</a> </h5> |
− | + | <br><br> | |
+ | Ultimately, we weighed impact and feasibility in our design and proposed the following strategy for our device, detailed in the graphic below. Most immediately, the technology we worked on developing this year could be best utilized by researchers for the immediate quantification of hormones in samples, following appropriate testing and clinical trials this device could benefit researchers as a non-invasive method of measuring salivary analytes. After the product has gained validation by clinicans, we would hope that the device could be used for non-verbally expressive individuals, such as those suffering from neurodevelopmental disorders to gauge well-being. Additionally, this device may have application in those suffering from neurodegenerative disease as a tool to gauge their well-being. Lastly, if the device is approved for such an indication, it may benefit wider audiences to track hormone levels and gain greater visibility to their endocrine health. | ||
+ | </p> | ||
+ | <br> | ||
+ | <h4 style="width:70%;margin-left:15%">Market Direction Analysis Summary</h4> | ||
+ | <br> | ||
+ | |||
+ | <div class="timeline" style="width:70%;margin-left:15%"> | ||
+ | <div class="box" style="width:70%;margin-left:15%"> | ||
+ | <h3 >Use by parents to monitor child’s stress levels and general well-being</h3> | ||
+ | <div class="row" > | ||
+ | <div class="column" > | ||
+ | <h5 >Pros</h5> | ||
+ | <ul > | ||
+ | <li>Can remove any communication barriers between parent and child</li> | ||
+ | <li>Ability to measure Δ cortisol could be useful in evaluating changes over time</li> | ||
+ | <li>Useful in the early detection of illness and prevention of Sudden Infant Death Syndrome (SIDS)</li> | ||
+ | </ul> | ||
</div> | </div> | ||
− | + | <div class="column" > | |
− | < | + | <h5>Cons</h5> |
− | + | <ul> | |
− | + | <li>Continual monitoring may lead to more anxiety in parents</li> | |
− | + | <li>Expensive technology</li> | |
+ | <li>Difficulties in establishing a baseline</li> | ||
+ | <li>Knowing the information does not have a substantial effect; minimal chance for intervention</li> | ||
+ | </ul> | ||
</div> | </div> | ||
+ | </div> | ||
</div> | </div> | ||
+ | <!-- <div class="container left"> | ||
+ | <div class="content" style="background-color:#44D9E6;"> | ||
+ | <p>Useful in the early detection of illness & Prevention of Sudden Infant Death Syndrome</p> | ||
+ | </div> | ||
+ | </div> | ||
+ | <div class="container right"> | ||
+ | <div class="content" style="background-color:#33A3AD;"> | ||
+ | <p>Will lead to more anxiety on the parental end</p> | ||
+ | </div> | ||
+ | </div> | ||
+ | --> | ||
+ | <br> | ||
+ | <br> | ||
+ | <br> | ||
− | < | + | <div class="box" style="width:70%;margin-left:15%"> |
− | + | <h3>Used as a diagnostic tool in clinical settings</h3> | |
− | <div class=" | + | <div class="row"> |
− | <div class=" | + | <div class="column"> |
− | < | + | <h5>Pros</h5> |
− | < | + | <ul> |
− | + | <li>Non-invasive procedure</li> | |
− | + | <li>Instant results could facilitate faster diagnosis leading to earlier intervention</li> | |
− | + | <li>Could aid in current diagnostic test of endocrine disorders, The Dexamethasone Suppression test, for </li> | |
+ | <li>Could help reduce extensive wait times in clinics or Emergency Room (ER)</li> | ||
+ | <li>Little training required to operate.</li> | ||
+ | </ul> | ||
</div> | </div> | ||
− | + | <div class="column"> | |
− | + | <h5>Cons</h5> | |
− | + | <ul> | |
− | + | <li>Concerns about biomarkers in saliva being as accurate as plasma samples</li> | |
− | + | <li>Sensitivity and specificity must be very high for proper diagnosis</li> | |
− | + | </ul> | |
</div> | </div> | ||
− | + | </div> | |
− | + | </div> | |
− | + | <br> | |
− | < | + | <br> |
− | + | <br> | |
+ | |||
+ | |||
+ | <div class="box" style="width:70%;margin-left:15%"> | ||
+ | <h3>Use in monitoring treatment in clinical settings</h3> | ||
+ | <div class="row"> | ||
+ | <div class="column"> | ||
+ | <h5>Pros</h5> | ||
+ | <ul> | ||
+ | <li>Non-invasive method Instant and ongoing surveillance</li> | ||
+ | <li>Could be used to evaluate metabolism of hormone</li> | ||
+ | <li>Help to determine personalised treatment plan and dosage</li> | ||
+ | <li>Could be useful in determining effectiveness of a treatment</li> | ||
+ | </ul> | ||
</div> | </div> | ||
− | + | <div class="column"> | |
− | < | + | <h5>Cons</h5> |
− | + | <ul> | |
− | + | <li>Concerns about biomarkers in saliva being as accurate as plasma samples</li> | |
− | + | <li>Expensive to replace cartridges</li> | |
+ | </ul> | ||
</div> | </div> | ||
− | + | </div> | |
− | + | </div> | |
− | + | <br> | |
− | < | + | <br> |
− | + | <br> | |
+ | |||
+ | |||
+ | <div class="box" style="background-color:#E3F2FD;" style="width:70%;margin-left:15%"> | ||
+ | <h3>Used in research studies to monitor levels of specific biomarker(s) in saliva</h3> | ||
+ | <div class="row" > | ||
+ | <div class="column"> | ||
+ | <h5>Pros</h5> | ||
+ | <ul> | ||
+ | <li>Could replace disruptive method of salivary collection</li> | ||
+ | <li>Could reveal critical information missed in current studies</li> | ||
+ | <li>Easier to complete studies with young children and infants</li> | ||
+ | </ul> | ||
</div> | </div> | ||
− | + | <div class="column" > | |
− | < | + | <h5>Cons</h5> |
− | + | <ul> | |
− | + | <li>Would need different designs that don’t interrupt the studies and are less noticeable</li> | |
− | + | <li>Would need different designs to use in studies with people of all ages</li> | |
+ | <li>Must be incredibly sensitive and specific for the desired biomarker</li> | ||
+ | </ul> | ||
</div> | </div> | ||
− | + | </div> | |
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
</div> | </div> | ||
+ | </div> | ||
+ | |||
+ | <br> | ||
+ | <br> | ||
+ | <footer style="background-color: #212121;height:90px "> | ||
+ | <div class="container"> | ||
+ | <div class="row"> | ||
+ | <div class="col-md-4"> | ||
+ | <ul class="list-inline quicklinks"> | ||
+ | <li><a href="https://igem.org/Main_Page" style="color:white; font-size:16pt">iGEM Headquarters</a> | ||
+ | </li> | ||
+ | </ul> | ||
+ | </div> | ||
+ | <div class="col-md-4"> | ||
+ | <ul class="list-inline social-buttons" style="margin-left:20%"> | ||
+ | <li><a href="https://twitter.com/iGEMQueens"style=" display: block; | ||
+ | background-color: #fff; | ||
+ | height: 40px; | ||
+ | width: 40px; | ||
+ | border-radius: 100%; | ||
+ | font-size: 20px; | ||
+ | line-height: 40px; | ||
+ | color: #000; | ||
+ | outline: 0; | ||
+ | -webkit-transition: all .3s; | ||
+ | -moz-transition: all .3s; | ||
+ | transition: all .3;"><i class="fa fa-twitter"style="color:black; font-family:FontAwesome;margin-left:10.75px;"></i></a> | ||
+ | </li> | ||
+ | <li><a href="https://www.facebook.com/iGEMQueens/?fref=ts"style=" display: block; | ||
+ | background-color: #fff; | ||
+ | height: 40px; | ||
+ | width: 40px; | ||
+ | border-radius: 100%; | ||
+ | font-size: 20px; | ||
+ | line-height: 40px; | ||
+ | color: #000; | ||
+ | outline: 0; | ||
+ | -webkit-transition: all .3s; | ||
+ | -moz-transition: all .3s; | ||
+ | transition: all .3;"><i class="fa fa-facebook"style="color:black;font-family:FontAwesome;margin-left:10.75px;"></i></a> | ||
+ | </li> | ||
+ | <li><a href="mailto:director@qgemteam.com" style=" display: block; | ||
+ | background-color: #fff; | ||
+ | height: 40px; | ||
+ | width: 40px; | ||
+ | border-radius: 100%; | ||
+ | font-size: 20px; | ||
+ | line-height: 40px; | ||
+ | color: #000; | ||
+ | outline: 0; | ||
+ | -webkit-transition: all .3s; | ||
+ | -moz-transition: all .3s; | ||
+ | transition: all .3;"><i class="fa fa-envelope"style="color:black;font-family:FontAwesome;margin-left:10.75px;"></i></a> | ||
+ | </li> | ||
+ | <li><a href="https://www.linkedin.com/company/1633448?trk=tyah&trkInfo=clickedVertical%3Acompany%2CclickedEntityId%3A1633448%2Cidx%3A1-1-1%2CtarId%3A1464110668532%2Ctas%3Aqgem" style=" display: block; | ||
+ | background-color: #fff; | ||
+ | height: 40px; | ||
+ | width: 40px; | ||
+ | border-radius: 100%; | ||
+ | font-size: 20px; | ||
+ | line-height: 40px; | ||
+ | color: #000; | ||
+ | outline: 0; | ||
+ | -webkit-transition: all .3s; | ||
+ | -moz-transition: all .3s; | ||
+ | transition: all .3;"><i class="fa fa-linkedin"style="color:black; font-family:FontAwesome;margin-left:10.75px;"></i></a> | ||
+ | </li> | ||
+ | </ul> | ||
+ | </div> | ||
+ | <div class="col-md-4"> | ||
+ | <ul class="list-inline quicklinks" style="color: white;font-size:16pt;"> | ||
+ | <li><a href="http://www.queensu.ca/" style="color:white;">Queen's University</a> | ||
+ | </li> | ||
+ | </ul> | ||
+ | </div> | ||
+ | </div> | ||
+ | </div> | ||
+ | </footer> | ||
</body> | </body> | ||
</html> | </html> |
Latest revision as of 03:14, 18 October 2018
Market Direction Analysis
Following our interview series, we reflected on all the insight we had gained from the various experts, parents, and community members. We came to the conclusion, that the use of the diagnostic pacifier device, was perhaps not best fit in the hands of all parents, because they may lack the scientific literacy to properly interpret fluctuations in their child's hormone levels. Additionally we received specific feedback on our pacifiers design and implemented the experts advice into our next iteration of the design seen here.
Ultimately, we weighed impact and feasibility in our design and proposed the following strategy for our device, detailed in the graphic below. Most immediately, the technology we worked on developing this year could be best utilized by researchers for the immediate quantification of hormones in samples, following appropriate testing and clinical trials this device could benefit researchers as a non-invasive method of measuring salivary analytes. After the product has gained validation by clinicans, we would hope that the device could be used for non-verbally expressive individuals, such as those suffering from neurodevelopmental disorders to gauge well-being. Additionally, this device may have application in those suffering from neurodegenerative disease as a tool to gauge their well-being. Lastly, if the device is approved for such an indication, it may benefit wider audiences to track hormone levels and gain greater visibility to their endocrine health.
Market Direction Analysis Summary
Use by parents to monitor child’s stress levels and general well-being
Pros
- Can remove any communication barriers between parent and child
- Ability to measure Δ cortisol could be useful in evaluating changes over time
- Useful in the early detection of illness and prevention of Sudden Infant Death Syndrome (SIDS)
Cons
- Continual monitoring may lead to more anxiety in parents
- Expensive technology
- Difficulties in establishing a baseline
- Knowing the information does not have a substantial effect; minimal chance for intervention
Used as a diagnostic tool in clinical settings
Pros
- Non-invasive procedure
- Instant results could facilitate faster diagnosis leading to earlier intervention
- Could aid in current diagnostic test of endocrine disorders, The Dexamethasone Suppression test, for
- Could help reduce extensive wait times in clinics or Emergency Room (ER)
- Little training required to operate.
Cons
- Concerns about biomarkers in saliva being as accurate as plasma samples
- Sensitivity and specificity must be very high for proper diagnosis
Use in monitoring treatment in clinical settings
Pros
- Non-invasive method Instant and ongoing surveillance
- Could be used to evaluate metabolism of hormone
- Help to determine personalised treatment plan and dosage
- Could be useful in determining effectiveness of a treatment
Cons
- Concerns about biomarkers in saliva being as accurate as plasma samples
- Expensive to replace cartridges
Used in research studies to monitor levels of specific biomarker(s) in saliva
Pros
- Could replace disruptive method of salivary collection
- Could reveal critical information missed in current studies
- Easier to complete studies with young children and infants
Cons
- Would need different designs that don’t interrupt the studies and are less noticeable
- Would need different designs to use in studies with people of all ages
- Must be incredibly sensitive and specific for the desired biomarker