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{{Ecuador}} | {{Ecuador}} | ||
+ | {{Ecuador/slide_script}} | ||
<html> | <html> | ||
− | + | <style> | |
− | + | @import url('https://fonts.googleapis.com/css?family=Raleway'); | |
− | @import url('https://fonts.googleapis.com/css?family= | + | |
*{ | *{ | ||
margin: 0px; | margin: 0px; | ||
− | font-family: ' | + | font-family: 'Raleway', sans-serif; |
+ | } | ||
+ | @keyframes slide-in { | ||
+ | from { | ||
+ | margin-left: -100%; | ||
+ | border-bottom-right-radius: 30px; | ||
+ | border-top-right-radius: 30px; | ||
} | } | ||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | + | to { | |
− | + | margin-left: 0%; | |
− | + | border-bottom-right-radius: 0; | |
− | + | border-top-right-radius: 0px; | |
− | + | ||
} | } | ||
+ | } | ||
− | + | @keyframes slide-in-menu { | |
− | + | from { | |
− | + | margin-left: -120%; | |
− | + | border-bottom-right-radius: 30px; | |
+ | border-top-right-radius: 30px; | ||
+ | opacity: 0.5; | ||
+ | } | ||
− | + | to { | |
− | + | margin-left: 0%; | |
− | + | border-bottom-right-radius: 0; | |
+ | border-top-right-radius: 0px; | ||
+ | opacity: 1; | ||
} | } | ||
− | + | } | |
− | + | ||
+ | @keyframes fade-in { | ||
+ | from { | ||
+ | opacity: 0; | ||
} | } | ||
− | + | ||
− | + | to { | |
− | + | opacity: 1; | |
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
} | } | ||
+ | } | ||
+ | |||
+ | @keyframes slide-in-oposite { | ||
+ | from { | ||
+ | margin-left: 100%; | ||
+ | } | ||
+ | |||
+ | to { | ||
+ | margin-left: 0%; | ||
+ | } | ||
+ | } | ||
+ | |||
+ | @keyframes slide-in-up { | ||
+ | from { | ||
+ | margin-top: 100%; | ||
+ | } | ||
+ | |||
+ | to { | ||
+ | margin-left: 0%; | ||
+ | } | ||
+ | } | ||
+ | |||
+ | @keyframes slide-in-up-oposite { | ||
+ | from { | ||
+ | margin-top: -100%; | ||
+ | } | ||
+ | |||
+ | to { | ||
+ | margin-left: 0%; | ||
+ | } | ||
+ | } | ||
+ | .igem_2018_team_menu.displaying_menu { | ||
+ | display: none; | ||
+ | } | ||
+ | .ecuador_menu { | ||
+ | font-size: 14px; | ||
+ | width: 100%; | ||
+ | height: 80px; | ||
+ | position: fixed; | ||
+ | left: 0px; | ||
+ | top: 15px; | ||
+ | background-color: #2471A3; | ||
+ | animation-name: fade-in; | ||
+ | animation-duration: 2s; | ||
+ | -webkit-box-shadow: 0px 3px 11px 0px rgba(0,0,0,0.75); | ||
+ | -moz-box-shadow: 0px 3px 11px 0px rgba(0,0,0,0.75); | ||
+ | box-shadow: 0px 3px 11px 0px rgba(0,0,0,0.75); | ||
+ | display: flex; | ||
+ | z-index: 5; | ||
+ | } | ||
.ecuador_home { | .ecuador_home { | ||
Line 55: | Line 102: | ||
display: flex; | display: flex; | ||
justify-content: center; | justify-content: center; | ||
− | background-color: # | + | background-color: #1F618D; |
position: absolute; | position: absolute; | ||
align-items: center; | align-items: center; | ||
Line 62: | Line 109: | ||
color: #FFF; | color: #FFF; | ||
transition: 0.5s; | transition: 0.5s; | ||
− | -webkit-box-shadow: inset - | + | -webkit-box-shadow: inset -50px -42px 114px -30px rgba(0,0,0,0.75); |
− | -moz-box-shadow: inset - | + | -moz-box-shadow: inset -50px -42px 114px -30px rgba(0,0,0,0.75); |
− | box-shadow: inset - | + | box-shadow: inset -50px -42px 114px -30px rgba(0,0,0,0.75); |
+ | z-index: 10; | ||
+ | |||
} | } | ||
.ecuador_home:hover { | .ecuador_home:hover { | ||
cursor: pointer; | cursor: pointer; | ||
− | font-size: | + | font-size: 16px; |
− | background-color: # | + | background-color: #1A5276; |
box-shadow: none; | box-shadow: none; | ||
} | } | ||
.menu_options_container { | .menu_options_container { | ||
− | + | width: 79%; | |
− | + | height: 50px; | |
+ | position: absolute; | ||
+ | left: 19%; | ||
+ | top: 15px; | ||
+ | display: flex; | ||
+ | justify-content: center; | ||
+ | } | ||
+ | |||
+ | .menu_option { | ||
+ | width: 14.28%; | ||
+ | height: 100%; | ||
+ | position: relative; | ||
+ | justify-content: center; | ||
+ | align-items: center; | ||
+ | display: flex; | ||
+ | color: #FFFFFF; | ||
+ | transition: 0.2s; | ||
+ | text-align: center; | ||
+ | } | ||
+ | |||
+ | #project { | ||
+ | animation-name: slide-in-up-oposite; | ||
+ | animation-duration: 0.5s; | ||
+ | animation-delay: 0.5s; | ||
+ | animation-fill-mode: backwards; | ||
+ | position: absolute; | ||
+ | left: 0%; | ||
+ | z-index: 9; | ||
+ | } | ||
+ | |||
+ | #parts { | ||
+ | animation-name: slide-in-up-oposite; | ||
+ | animation-duration: 0.5s; | ||
+ | animation-delay: 0.6s; | ||
+ | animation-fill-mode: backwards; | ||
+ | position: absolute; | ||
+ | left: 12.5%; | ||
+ | z-index: 9; | ||
+ | } | ||
+ | |||
+ | #human_practice { | ||
+ | animation-name: slide-in-up-oposite; | ||
+ | animation-duration: 0.5s; | ||
+ | animation-delay: 0.7s; | ||
+ | animation-fill-mode: backwards; | ||
+ | position: absolute; | ||
+ | left: 25%; | ||
+ | z-index: 9; | ||
+ | } | ||
+ | |||
+ | #safety { | ||
+ | animation-name: slide-in-up-oposite; | ||
+ | animation-duration: 0.5s; | ||
+ | animation-delay: 0.8s; | ||
+ | animation-fill-mode: backwards; | ||
+ | position: absolute; | ||
+ | left: 37.5%; | ||
+ | z-index: 9; | ||
+ | } | ||
+ | |||
+ | #interlab { | ||
+ | animation-name: slide-in-up-oposite; | ||
+ | animation-duration: 0.5s; | ||
+ | animation-delay: 0.9s; | ||
+ | animation-fill-mode: backwards; | ||
+ | position: absolute; | ||
+ | left: 50%; | ||
+ | z-index: 9; | ||
+ | } | ||
+ | |||
+ | #judging_forms { | ||
+ | animation-name: slide-in-up-oposite; | ||
+ | animation-duration: 0.5s; | ||
+ | animation-delay: 1s; | ||
+ | animation-fill-mode: backwards; | ||
+ | |||
+ | position: absolute; | ||
+ | left: 62.5%; | ||
+ | z-index: 9; | ||
+ | } | ||
+ | |||
+ | #team { | ||
+ | animation-name: slide-in-up-oposite; | ||
+ | animation-duration: 0.5s; | ||
+ | animation-delay: 1.1s; | ||
+ | animation-fill-mode: backwards; | ||
+ | position: absolute; | ||
+ | left: 75%; | ||
+ | z-index: 9; | ||
+ | } | ||
+ | #atributions { | ||
+ | animation-name: slide-in-up-oposite; | ||
+ | animation-duration: 0.5s; | ||
+ | animation-delay: 1.2s; | ||
+ | animation-fill-mode: backwards; | ||
+ | position: absolute; | ||
+ | left: 87.5%; | ||
+ | z-index: 9; | ||
+ | } | ||
+ | .ecuador_href_text { | ||
+ | width: 14.28% !important; | ||
+ | height: 100% !important; | ||
+ | position: relative !important; | ||
+ | justify-content: center !important; | ||
+ | align-items: center !important; | ||
+ | display: flex !important; | ||
+ | color: #FFFFFF !important; | ||
+ | transition: 0.2s !important; | ||
+ | text-align: center !important; | ||
+ | text-decoration: none !important; | ||
+ | font-weight: bold !important; | ||
+ | } | ||
+ | |||
+ | .ecuador_href_sub_text { | ||
+ | width: 100% !important; | ||
+ | height: 40px !important; | ||
+ | position: relative !important; | ||
+ | text-align: left !important; | ||
+ | text-indent: 20px !important; | ||
+ | display: flex !important; | ||
+ | background-color: #FFF !important; | ||
+ | margin: auto auto !important; | ||
+ | align-items: center !important; | ||
+ | transition: 0.2s !important; | ||
+ | color: #D5DBDB !important; | ||
+ | text-decoration: none !important; | ||
+ | } | ||
+ | |||
+ | .menu_option:hover { | ||
+ | margin-top: 3px; | ||
+ | cursor: pointer; | ||
+ | } | ||
+ | |||
+ | .menu_option:hover div.menu_sub_options_container{ | ||
+ | display: block; | ||
+ | } | ||
+ | |||
+ | .menu_sub_options_container { | ||
+ | width: 100%; | ||
+ | height: auto; | ||
+ | position: absolute; | ||
+ | top: 50px; | ||
+ | display: none; | ||
+ | } | ||
+ | |||
+ | .sub_menu_option { | ||
+ | width: 100%; | ||
+ | height: 40px; | ||
+ | position: relative; | ||
+ | text-align: left; | ||
+ | text-indent: 20px; | ||
+ | display: flex; | ||
+ | background-color: #000; | ||
+ | margin: auto auto; | ||
+ | align-items: center; | ||
+ | transition: 0.2s; | ||
+ | color: #D5DBDB; | ||
+ | } | ||
+ | |||
+ | .sub_menu_option:hover { | ||
+ | text-indent: 15px; | ||
+ | background-color: #2E86C1; | ||
+ | } | ||
+ | |||
+ | .ecuador_footer { | ||
+ | width: 100%; | ||
+ | height: 250px; | ||
+ | position: relative; | ||
+ | left: 0px; | ||
+ | background-color: #212F3C; | ||
+ | } | ||
+ | |||
+ | .ecuador_footer_igem_logo { | ||
+ | width: 180px; | ||
+ | height: 180px; | ||
+ | position: absolute; | ||
+ | right: 80px; | ||
+ | top: 35px; | ||
+ | background-image: url(https://static.igem.org/mediawiki/2018/5/55/T--Ecuador--iGEM--Logo--Black.png); | ||
+ | background-size: 100%; | ||
+ | background-repeat: no-repeat; | ||
+ | background-position: center; | ||
+ | } | ||
+ | |||
+ | .ecuador_footer_information_layout { | ||
+ | width: 75%; | ||
+ | height: 80%; | ||
position: absolute; | position: absolute; | ||
− | left: | + | left: 60px; |
− | top: | + | top: 15%; |
display: flex; | display: flex; | ||
− | |||
} | } | ||
− | . | + | .ecuador_footer_information_container { |
− | width: | + | width: 33.33%; |
height: 100%; | height: 100%; | ||
position: relative; | position: relative; | ||
− | + | } | |
− | + | ||
− | + | .ecuador_footer_information_title_container { | |
− | + | width: 100%; | |
− | + | height: 25px; | |
+ | position: relative; | ||
+ | top: 0px; | ||
text-align: center; | text-align: center; | ||
+ | font-size: 20px; | ||
+ | font-weight: bold; | ||
+ | color: #B2BABB; | ||
} | } | ||
− | . | + | .ecuador_follow_us_icons_container { |
− | margin- | + | width: 50%; |
+ | height: 60px; | ||
+ | position: relative; | ||
+ | top: 40px; | ||
+ | margin: auto; | ||
+ | display: flex; | ||
+ | } | ||
+ | .ecuador_information_data_container{ | ||
+ | width: 50%; | ||
+ | height: 60px; | ||
+ | position: relative; | ||
+ | top: 55px; | ||
+ | margin: auto; | ||
+ | display: flex; | ||
+ | } | ||
+ | |||
+ | .ecuador_follow_us_icon { | ||
+ | width: 70px; | ||
+ | height: 60px; | ||
+ | position: relative; | ||
+ | margin: auto; | ||
+ | } | ||
+ | |||
+ | #facebook { | ||
+ | background-image: url(https://static.igem.org/mediawiki/2018/4/42/T--Ecuador--Facebook.png); | ||
+ | background-repeat: no-repeat; | ||
+ | background-position: center; | ||
+ | background-size: 80%; | ||
+ | transition: 0.4s; | ||
+ | border-radius: 5px; | ||
+ | } | ||
+ | |||
+ | #facebook:hover { | ||
+ | background-image: url(https://static.igem.org/mediawiki/2018/4/40/T--Ecuador--Facebook--White.png); | ||
cursor: pointer; | cursor: pointer; | ||
} | } | ||
− | . | + | #instagram { |
− | + | background-image: url(https://static.igem.org/mediawiki/2018/9/90/T--Ecuador--Instagram.png); | |
+ | background-repeat: no-repeat; | ||
+ | background-position: center; | ||
+ | background-size: 80%; | ||
+ | transition: 0.4s; | ||
+ | border-radius: 5px; | ||
} | } | ||
− | . | + | #instagram:hover { |
− | width: | + | background-image: url(https://static.igem.org/mediawiki/2018/4/49/T--Ecuador--Instagram--White.png); |
− | height: | + | cursor: pointer; |
− | position: | + | } |
− | top: | + | |
+ | .ecuador_down_arrow_container { | ||
+ | width: 130px; | ||
+ | height: 130px; | ||
+ | position: relative; | ||
+ | bottom: 180px; | ||
+ | left: 85%; | ||
+ | background-image: url(https://static.igem.org/mediawiki/2018/d/db/T--Ecuador--Down--Arrow.png); | ||
+ | background-position: center; | ||
+ | background-repeat: no-repeat; | ||
+ | background-size: 65%; | ||
+ | animation-name: fade-in; | ||
+ | animation-duration: 1s; | ||
+ | animation-fill-mode: backwards; | ||
+ | animation-delay: 3s; | ||
+ | transition: 0.5s; | ||
+ | } | ||
+ | |||
+ | .ecuador_down_arrow_container:hover { | ||
+ | transform: scale(1.20); | ||
+ | cursor: pointer; | ||
+ | } | ||
+ | |||
+ | .ecuador_team_icon { | ||
+ | width: 100%; | ||
+ | height: 750px; | ||
+ | position: relative; | ||
+ | left: 0px; | ||
+ | top: 0px; | ||
+ | margin-top: 10px; | ||
background-color: #FFF; | background-color: #FFF; | ||
− | + | ||
− | + | background-position: center; | |
+ | background-repeat: no-repeat; | ||
+ | background-size: 70%; | ||
+ | animation-name: fade-in; | ||
+ | animation-duration: 4s; | ||
} | } | ||
− | . | + | .ecuador_project_description_container { |
width: 100%; | width: 100%; | ||
− | height: | + | height: 800px; |
+ | background-color: #333333; | ||
position: relative; | position: relative; | ||
− | + | transform: skewY(2deg); | |
− | + | ||
display: flex; | display: flex; | ||
− | |||
− | |||
− | |||
− | |||
− | |||
} | } | ||
− | . | + | .ecuador_proyect_description_text_container { |
− | + | transform: skewY(-2deg); | |
+ | width: 40%; | ||
+ | height: 50%; | ||
+ | position: relative; | ||
+ | margin-top: 170px; | ||
+ | justify-content: center; | ||
} | } | ||
− | . | + | .ecuador_project_description_video_container { |
+ | width: 60%; | ||
+ | height: 70%; | ||
+ | transform: skewY(-2deg); | ||
+ | position: relative; | ||
+ | margin-top: 90px; | ||
+ | } | ||
+ | |||
+ | .ecuador_home_content { | ||
width: 100%; | width: 100%; | ||
− | height: | + | height: auto; |
position: absolute; | position: absolute; | ||
left: 0px; | left: 0px; | ||
− | |||
− | |||
} | } | ||
− | . | + | .ecuador_proyect_description_main_text_container { |
+ | width: 80%; | ||
+ | height: auto; | ||
+ | margin: auto; | ||
+ | margin-top: 100px; | ||
+ | color: #FFF; | ||
+ | font-size: 60px; | ||
+ | text-align: center; | ||
+ | text-indent: 20px; | ||
+ | animation-name: fade-in; | ||
+ | animation-duration: 1s; | ||
+ | animation-delay: 0.1s; | ||
+ | animation-fill-mode: backwards; | ||
+ | display: none; | ||
+ | line-height: 1; | ||
+ | } | ||
+ | |||
+ | .ecuador_proyect_description_sub_text_container { | ||
+ | width: 40%; | ||
+ | height: auto; | ||
+ | margin: auto; | ||
+ | margin-top: 60px; | ||
+ | color: #FFF; | ||
+ | font-size: 30px; | ||
+ | text-align: center; | ||
+ | text-indent: 20px; | ||
+ | animation-name: fade-in; | ||
+ | animation-duration: 1s; | ||
+ | animation-delay: 0.5s; | ||
+ | animation-fill-mode: backwards; | ||
+ | display: none; | ||
+ | line-height: 1; | ||
+ | } | ||
+ | .ecuador_down_arrow_container_description { | ||
+ | width: 130px; | ||
+ | height: 130px; | ||
+ | position: absolute; | ||
+ | left: 100px; | ||
+ | bottom: 180px; | ||
+ | background-image: url(https://static.igem.org/mediawiki/2018/d/db/T--Ecuador--Down--Arrow.png); | ||
+ | background-position: center; | ||
+ | background-repeat: no-repeat; | ||
+ | background-size: 65%; | ||
+ | animation-name: fade-in; | ||
+ | animation-duration: 1s; | ||
+ | animation-fill-mode: backwards; | ||
+ | animation-delay: 1.5s; | ||
+ | transition: 0.5s; | ||
+ | transform: scaleX(-1); | ||
+ | display: none; | ||
+ | } | ||
+ | |||
+ | .ecuador_down_arrow_container_description:hover { | ||
+ | bottom: 170px; | ||
+ | cursor: pointer; | ||
+ | } | ||
+ | |||
+ | .ecuador_description_abstract_container { | ||
width: 100%; | width: 100%; | ||
− | height: | + | height: 720px; |
− | background-color: # | + | position: relative; |
+ | transform: skewY(-2deg); | ||
+ | display: block; | ||
+ | background-color: #23496E; | ||
+ | margin-top: -70px; | ||
+ | z-index: 2; | ||
+ | } | ||
+ | |||
+ | .ecuador_description_abstract_container_title { | ||
+ | transform: skewY(2deg); | ||
+ | width: 100%; | ||
+ | height: auto; | ||
+ | position: relative; | ||
+ | font-size: 40px; | ||
+ | display: flex; | ||
+ | justify-content: center; | ||
+ | color: #FFF; | ||
+ | top: 100px; | ||
+ | animation-name: fade-in; | ||
+ | animation-duration: 1s; | ||
+ | animation-fill-mode: backwards; | ||
+ | text-align: center; | ||
+ | display: none; | ||
+ | } | ||
+ | |||
+ | .ecuador_description_abstract_text_container { | ||
+ | width: 80%; | ||
+ | height: auto; | ||
+ | transform: skewY(2deg); | ||
+ | top: 160px; | ||
+ | color: #FFF; | ||
+ | font-size: 20px; | ||
+ | position: relative; | ||
+ | margin: auto; | ||
+ | text-align: justify; | ||
+ | animation-name: fade-in; | ||
+ | animation-duration: 1s; | ||
+ | animation-delay: 0.75s; | ||
+ | animation-fill-mode: backwards; | ||
+ | display: none; | ||
+ | line-height: 2.6; | ||
+ | } | ||
+ | |||
+ | .ecuador_description_separator { | ||
+ | width: 100%; | ||
+ | height: 250px; | ||
+ | background-color: #23496E; | ||
+ | position: relative; | ||
+ | margin-top: -100px; | ||
+ | z-index: 1; | ||
+ | } | ||
+ | |||
+ | .description_video { | ||
position: absolute; | position: absolute; | ||
− | + | right: 200px; | |
− | top: | + | top: 80px; |
+ | width: 60%; | ||
+ | height: 55%; | ||
} | } | ||
+ | |||
+ | .cientific_name_text { | ||
+ | font-style: italic; | ||
+ | } | ||
+ | |||
+ | @media only screen and (max-device-width: 600px) { | ||
+ | .ecuador_team_icon { | ||
+ | display: none; | ||
+ | } | ||
+ | |||
+ | .ecuador_proyect_description_text_container { | ||
+ | width: 0%; | ||
+ | display: none; | ||
+ | } | ||
+ | |||
+ | .ecuador_project_description_video_container { | ||
+ | width: 100%; | ||
+ | } | ||
+ | |||
+ | .ecuador_down_arrow_container_description { | ||
+ | display: none; | ||
+ | width: 0%; | ||
+ | } | ||
+ | |||
+ | .ecuador_down_arrow_container { | ||
+ | display: none; | ||
+ | width: 0%; | ||
+ | } | ||
+ | |||
+ | .ecuador_project_description_container { | ||
+ | height: 600px; | ||
+ | } | ||
+ | |||
+ | .description_video { | ||
+ | position: relative; | ||
+ | width: 60%; | ||
+ | height: 95%; | ||
+ | left: 1%; | ||
+ | } | ||
+ | |||
+ | .ecuador_description_abstract_text_container { | ||
+ | display: block; | ||
+ | font-size: 14px; | ||
+ | } | ||
+ | |||
+ | .ecuador_description_abstract_container_title { | ||
+ | display: block; | ||
+ | } | ||
+ | |||
+ | .ecuador_project_description_video_container { | ||
+ | width: 100%; | ||
+ | height: 300px; | ||
+ | justify-content: center; | ||
+ | display: flex; | ||
+ | } | ||
+ | |||
+ | .menu_options_container { | ||
+ | display: none; | ||
+ | } | ||
+ | |||
+ | .ecuador_home { | ||
+ | font-size: 12px; | ||
+ | } | ||
+ | |||
+ | .ecuador_description_abstract_container { | ||
+ | height: 1400px; | ||
+ | } | ||
+ | |||
+ | .ecuador_footer { | ||
+ | display: none; | ||
+ | } | ||
+ | } | ||
+ | |||
+ | .ecuador_sponsors_icons_container { | ||
+ | width: 100%; | ||
+ | height: 60px; | ||
+ | position: relative; | ||
+ | top: 40px; | ||
+ | margin: auto; | ||
+ | display: flex; | ||
+ | } | ||
+ | .ecuador_sponsors_icon { | ||
+ | width: 60px; | ||
+ | height: 60px; | ||
+ | position: relative; | ||
+ | margin-right: 4px; | ||
+ | margin-left: 4px; | ||
+ | } | ||
+ | #ing_bio{ | ||
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− | + | We are developing a novel biomaterial for biomedical applications based on the cross-linking of bacterial cellulose (BC) and a fusion protein with modules carbohydrate binding domain (CBD) for binding to cellulose, elastin-like polypeptides (ELP) and bone morphogenic protein 2 (BMP-2). The production of this biomaterial is being carried out with synthetic biology techniques using two differents Escherichia coli expression systems. The first one produces bacterial celullose and the second one produces the fusion protein CBD-ELP-BMP2. | |
+ | <br/> | ||
+ | <br/> | ||
+ | |||
+ | Bacterial cellulose is used as a matrix because of the biocompatibility with the human body and has the potential to regulate cell adhesion, that is an important characteristic to be used as a scaffold. ELP is a structural protein which confers new physicochemical characteristics to the biomaterial such us a transition temperature that allows the biomaterial to be as a hydrogel. On the other hand, the BMP2 protein, is an inducer of cell differentiation in osteoblasts, which confers bone tissue regeneration property. | ||
+ | |||
+ | |||
+ | <br/> | ||
+ | <br/> | ||
+ | |||
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− | |||
</html> | </html> | ||
+ | {{Ecuador/footer}} |
Latest revision as of 18:26, 25 November 2018
IdealImageSlider
Captions Extension v1.0.1
What is C-lastin?
Know our idea
About our project
We are developing a novel biomaterial for biomedical applications based on the cross-linking of bacterial cellulose (BC) and a fusion protein with modules carbohydrate binding domain (CBD) for binding to cellulose, elastin-like polypeptides (ELP) and bone morphogenic protein 2 (BMP-2). The production of this biomaterial is being carried out with synthetic biology techniques using two differents Escherichia coli expression systems. The first one produces bacterial celullose and the second one produces the fusion protein CBD-ELP-BMP2.
Bacterial cellulose is used as a matrix because of the biocompatibility with the human body and has the potential to regulate cell adhesion, that is an important characteristic to be used as a scaffold. ELP is a structural protein which confers new physicochemical characteristics to the biomaterial such us a transition temperature that allows the biomaterial to be as a hydrogel. On the other hand, the BMP2 protein, is an inducer of cell differentiation in osteoblasts, which confers bone tissue regeneration property.
Bacterial cellulose is used as a matrix because of the biocompatibility with the human body and has the potential to regulate cell adhesion, that is an important characteristic to be used as a scaffold. ELP is a structural protein which confers new physicochemical characteristics to the biomaterial such us a transition temperature that allows the biomaterial to be as a hydrogel. On the other hand, the BMP2 protein, is an inducer of cell differentiation in osteoblasts, which confers bone tissue regeneration property.