Difference between revisions of "Team:CPU CHINA/Human Practices"

 
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<h1>Human Practices</h1>
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At iGEM we believe societal considerations should be upfront and integrated throughout the design and execution of synthetic biology projects. “Human Practices” refers to iGEM teams’ efforts to actively consider how the world affects their work and the work affects the world. Through your Human Practices activities, your team should demonstrate how you have thought carefully and creatively about whether your project is responsible and good for the world. We invite you to explore issues relating (but not limited) to the ethics, safety, security, and sustainability of your project, and to show how this exploration feeds back into your project purpose, design and execution.
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<h1>Human practice summary for silver medal
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<h4>Through series of visiting and interviews with professionals (learn the details below in integrated human practice summary), we were eventually able to apply our RNA interference strategy to HCC therapeutic. Then we continued our human practice by promoting the public awareness of HCC, our project and synthetic biology.
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<br/>
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<h4>First, we were curious as to how people view HCC. So a public survey about HCC was conducted, and then we realized that their understanding about this deadly disease is generally shallow and misguided. In light of such situation we felt the need for a booklet which is now accessible online in which basic HCC prevention and treatment are discussed.
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<br/>
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<h4><a href="https://2018.igem.org/Team:CPU_CHINA/Engagement">Please click here to see survey and interview.</a></h4>
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<h4><a href="https://2018.igem.org/Team:CPU_CHINA/HP/Silver">Please click here to see booklet.</a></h4>
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<br/>
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<h4>Then, to widen the impact of our project on campus, we organized an Innovation Experiment for College Students study group based on our RNAi system and three junior students joined to learn our project. They were able to practice some experimental techniques such as molecular cloning.
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<br/>
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<h4><a href="https://2018.igem.org/Team:CPU_CHINA/HP/Silver?club=1">Please click here to see Bio-X Club.</a></h4>
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<h4><a href="https://static.igem.org/mediawiki/2018/d/d1/T--CPU_CHINA--HP_dachuang.pdf">Please click here to see Innovation Experiment.</a></h4>
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<br/>
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<br/>
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<h4>Promoting synthetic biology has always been our mission, this iGEM season marks the third year of our life science student club CPU Bio-X Club. The popularity of this club elevated greatly this year with weekly professional lectures and a big campus-ranged event. We also tried some other novel ways including the TED<sup>x</sup> speech “<i>Synthetic biology, creating a better future</i>” and on-street interviews.
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<br/>
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<h4><a href="https://2018.igem.org/Team:CPU_CHINA/HP/Silver">Please click here to see TED.</a></h4>
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<h1>Integrated human practice summary
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<br/>
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<h4>This year, CPU-CHINA conducted integrated human practices by link it with the design of our project, not only in parts design, but also in our future business plan since we were eager to develop a therapy that suits public needs. In the first place, we developed a highly selective novel RNA interference strategy and hoped that it could be applied to certain diseases. We interviewed with clinical oncologists, researched on relevant literature and decided on HCC. We also added disease-specific promoters which could help reduce side effects usually involved in cancer therapy, as well as a small-molecule-dependent switch which would be useful for individual administration through our interview and literature researching as well.
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<br/>
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<h4><a href="https://static.igem.org/mediawiki/2018/5/58/T--CPU_CHINA--hp-linchuangyishengcaifang.pdf">Please click here to see the system.</a></h4>
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<h4><a href="https://2018.igem.org/Team:CPU_CHINA/HP/Gold_Integrated">Please click here to see the interview with the doctor.</a></h4>
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<br/>
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<h4>Since the specific parts had been designed, testing the practical plausibility of our application became the priority. We interviewed with several business experts to discuss the project in real business settings, which led to a business plan. In that plan we thoroughly considered the current market, our competition and our strength.
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<br/>
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<h4><a href="https://2018.igem.org/Team:CPU_CHINA/HP/Gold_Integrated?business=1">Please click here to see our Entrepreneurship Proposal.</a></h4>
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<h4>Last, we tried to learn patients’ reflection about our strategy. We once thought they might feel reluctant because gene therapy is not the most common method for cancer treatment, but soon we found that such concern was unnecessary. We communicated with patients from a huge cancer association, especially one that has much benefitted from novel cancer therapy. He confirmed the significance of specific and effective drugs regardless of how anything is popular at the moment.
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<br/>
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<h4><a href="https://2018.igem.org/Team:CPU_CHINA/HP/Gold_Integrated?patients">Please click here to see the interviews with patients.</a></h4>
  
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<p>For more information, please see the <a href="https://2018.igem.org/Human_Practices">Human Practices Hub</a>. There you will find:</p>
 
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<li> an <a href="https://2018.igem.org/Human_Practices/Introduction">introduction</a> to Human Practices at iGEM </li>
 
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<li>tips on <a href="https://2018.igem.org/Human_Practices/How_to_Succeed">how to succeed</a> including explanations of judging criteria and advice about how to conduct and document your Human Practices work</li>
 
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<li>descriptions of <a href="https://2018.igem.org/Human_Practices/Examples">exemplary work</a> to inspire you</li>
 
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<li>links to helpful <a href="https://2018.igem.org/Human_Practices/Resources">resources</a></li>
 
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<li>And more! </li>
 
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<p>On this page, your team should document all of your Human Practices work and activities. You should write about the Human Practices topics you considered in your project, document any activities you conducted to explore these topics (such as engaging with experts and stakeholders), describe why you took a particular approach (including referencing any work you built upon), and explain if and how you integrated takeaways from your Human Practices work back into your project purpose, design and/or execution. </p>
 
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<p>If your team has gone above and beyond in work related to safety, then you should document this work on your Safety wiki page and provide a description and link on this page. If your team has developed education and public engagement efforts that go beyond a focus on your particular project, and for which would like to nominate your team for the Best Education and Public Engagement Special Prize, you should document this work on your Education and Education wiki page and provide a description and link here. </p>
 
 
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<p>The iGEM judges will review this page to assess whether you have met the Silver and/or Gold medal requirements based on the Integrated Human Practices criteria listed below. If you nominate your team for the <a href="https://2018.igem.org/Judging/Awards">Best Integrated Human Practices Special Prize</a> by filling out the corresponding field in the <a href="https://2018.igem.org/Judging/Judging_Form">judging form</a>, the judges will also review this page to consider your team for that prize.
 
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<p>Convince the judges you have thought carefully and creatively about whether your work is responsible and good for the world. Document how you have investigated these issues and engaged with your relevant communities, why you chose this approach, and what you have learned. Please note that surveys will not fulfill this criteria unless you follow scientifically valid methods. </p>
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<h3>Gold Medal Criterion #1</h3>
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<p>Expand on your silver medal activity by demonstrating how you have integrated the investigated issues into the purpose, design and/or execution of your project. Document how your project has changed based upon your human practices work.
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<h3>Best Integrated Human Practices Special Prize</h3>
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<p>To compete for the Best Integrated Human Practices prize, please describe your work on this page and also fill out the description on the judging form. </p>
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<p>How does your project affect society and how does society influence the direction of your project? How might ethical considerations and stakeholder input guide your project purpose and design and the experiments you conduct in the lab? How does this feedback enter into the process of your work all through the iGEM competition? Document a thoughtful and creative approach to exploring these questions and how your project evolved in the process to compete for this award!</p>
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<p>You must also delete the message box on the top of this page to be eligible for this prize.</p>
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Latest revision as of 14:34, 6 December 2018

Human practice summary for silver medal

Through series of visiting and interviews with professionals (learn the details below in integrated human practice summary), we were eventually able to apply our RNA interference strategy to HCC therapeutic. Then we continued our human practice by promoting the public awareness of HCC, our project and synthetic biology.

First, we were curious as to how people view HCC. So a public survey about HCC was conducted, and then we realized that their understanding about this deadly disease is generally shallow and misguided. In light of such situation we felt the need for a booklet which is now accessible online in which basic HCC prevention and treatment are discussed.

Please click here to see survey and interview.

Please click here to see booklet.



Then, to widen the impact of our project on campus, we organized an Innovation Experiment for College Students study group based on our RNAi system and three junior students joined to learn our project. They were able to practice some experimental techniques such as molecular cloning.

Please click here to see Bio-X Club.

Please click here to see Innovation Experiment.



Promoting synthetic biology has always been our mission, this iGEM season marks the third year of our life science student club CPU Bio-X Club. The popularity of this club elevated greatly this year with weekly professional lectures and a big campus-ranged event. We also tried some other novel ways including the TEDx speech “Synthetic biology, creating a better future” and on-street interviews.

Please click here to see TED.

Integrated human practice summary

This year, CPU-CHINA conducted integrated human practices by link it with the design of our project, not only in parts design, but also in our future business plan since we were eager to develop a therapy that suits public needs. In the first place, we developed a highly selective novel RNA interference strategy and hoped that it could be applied to certain diseases. We interviewed with clinical oncologists, researched on relevant literature and decided on HCC. We also added disease-specific promoters which could help reduce side effects usually involved in cancer therapy, as well as a small-molecule-dependent switch which would be useful for individual administration through our interview and literature researching as well.

Please click here to see the system.

Please click here to see the interview with the doctor.


Since the specific parts had been designed, testing the practical plausibility of our application became the priority. We interviewed with several business experts to discuss the project in real business settings, which led to a business plan. In that plan we thoroughly considered the current market, our competition and our strength.

Please click here to see our Entrepreneurship Proposal.

Last, we tried to learn patients’ reflection about our strategy. We once thought they might feel reluctant because gene therapy is not the most common method for cancer treatment, but soon we found that such concern was unnecessary. We communicated with patients from a huge cancer association, especially one that has much benefitted from novel cancer therapy. He confirmed the significance of specific and effective drugs regardless of how anything is popular at the moment.

Please click here to see the interviews with patients.