ElishaKrauss (Talk | contribs) |
ElishaKrauss (Talk | contribs) |
||
Line 58: | Line 58: | ||
<div class="column full_size" style="width:70%;margin-left:15%"> | <div class="column full_size" style="width:70%;margin-left:15%"> | ||
<h1>Computer Aided Design</h1> | <h1>Computer Aided Design</h1> | ||
− | <p> | + | We created relevant hardware for our project including a 3D printed pacifier to passively collect saliva samples. Before 3D printing any iterations of our design, we modeled our device on Computer Aided Design Software. |
− | + | <p> <h2>Computer Aided Design and 3D Printing</h2> | |
− | + | <h3>Attempt 1</h3> | |
+ | <!-- 3 pics --> | ||
+ | <img src="https://static.igem.org/mediawiki/2018/d/d5/T--Queens_Canada--pacifier1.jpg"/> | ||
+ | <img src="https://static.igem.org/mediawiki/2018/9/9b/T--Queens_Canada--pacifier2.jpg"/> | ||
+ | <img src="https://static.igem.org/mediawiki/2018/f/f9/T--Queens_Canada--pacifier3.jpg" height="300"/> | ||
+ | <h5>Results:</h5> | ||
+ | <!-- 2 pics --> | ||
+ | <img src="https://static.igem.org/mediawiki/2018/5/58/T--Queens_Canada--pacifier4.jpg"/> | ||
+ | <img src="https://static.igem.org/mediawiki/2018/5/58/T--Queens_Canada--pacifier5.jpg"/> | ||
</p> | </p> | ||
</div> | </div> | ||
Line 66: | Line 74: | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
</div> | </div> | ||
<footer style="background-color: #212121;height:90px "> | <footer style="background-color: #212121;height:90px "> |
Revision as of 02:04, 11 October 2018
At team Queens Canada, we believe that proper preparation is the best way to reach a desired outcome. Accordingly, we sought to model many aspects of our project which aided in making the right choices in the lab and receiving positive results. Through the help of student on our team specializing in biomedical computing, applied mathematics, and chemical engineering, we created a number of different models that were crucial to our project design.
Molecular Dynamic Simulations
One of our constructs relied on linkers of sufficient length and flexibility to convert a conformational change, into signal transduction. We have achieved this through firstly modeling with PyMol [[[[LINK TO LINKER DEVELOPMENT TAB]]] and then performing molecular dynamic simulations of the root-mean-square deviation of atomic position [[[LINK TO Molecular Dynamics Tab]]]].