Ser Archer (Talk | contribs) |
Ser Archer (Talk | contribs) |
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} | } | ||
</style> | </style> | ||
− | <div style="inline-height: | + | <div style="inline-height:50px;position:relative;overflow:hidden;color:white;font-size;20px;top:200px;" id="introduction"> |
Hepatocellular carcinoma (HCC), also called malignant hepatoma, is one of the deadliest cancers. Through the introduction of a double-stranded RNA to the targeted messenger RNA (mRNA), RNA interference (RNAi) leads to the specific cleavage of the mRNA and efficient silencing of gene expression. Since RNAi could be used to silence genes involved in the development and progression of carcinomas, it has promising therapeutic potential for their treatment. The gene therapy strategy we propose here: | Hepatocellular carcinoma (HCC), also called malignant hepatoma, is one of the deadliest cancers. Through the introduction of a double-stranded RNA to the targeted messenger RNA (mRNA), RNA interference (RNAi) leads to the specific cleavage of the mRNA and efficient silencing of gene expression. Since RNAi could be used to silence genes involved in the development and progression of carcinomas, it has promising therapeutic potential for their treatment. The gene therapy strategy we propose here: | ||
(1) utilize two cancer-specific promoters (one HCC-specific) to open an AND-gated system to target HCC, the selectivity supposed to be extremely high; | (1) utilize two cancer-specific promoters (one HCC-specific) to open an AND-gated system to target HCC, the selectivity supposed to be extremely high; | ||
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$(document).ready(function(){ | $(document).ready(function(){ | ||
$("#introduction").css("width",$(window).width()*0.6+"px"); | $("#introduction").css("width",$(window).width()*0.6+"px"); | ||
− | $("#introduction").css("margin-left",$(window).width()*0. | + | $("#introduction").css("margin-left",$(window).width()*0.2+"px"); |
− | $("#href").css("margin-left",$(window).width()*0. | + | $("#href").css("margin-left",$(window).width()*0.2+"px"); |
}) | }) | ||
</script> | </script> | ||
</html> | </html> |
Revision as of 14:35, 27 June 2018
More relevant background information can be seen in Background