Difference between revisions of "Team:Queens Canada/Description"

(Prototype team page)
 
Line 5: Line 5:
  
 
<div class="column full_size">
 
<div class="column full_size">
<h1>Description</h1>
+
<h1>Biosensors utilizing ligand dependent intein-splicing: Application in a Diagnostic Pacifier</h1>
  
<p>Tell us about your project, describe what moves you and why this is something important for your team.</p>
+
<p>This year’s project will produce a novel, simple, portable, and point of care method for quantification of ligands present in a solution. To achieve this goal, we will be developing an engineered protein construct that utilizes ligand binding domains, intein-splicing, and a luminescent or fluorescent reporter domain. The resulting signal can then be measured and quantified, providing a dose-dependent method of measuring analytes. One application for this novel technology is to detect and quantify the amount of cortisol present in saliva. In addition to our engineered protein, we are building a complimentary pacifier with a built in luminometer detector. In practice, a child would be given the pacifier, which would allow for real time analysis of the baby’s salivary cortisol, and this information would then be wirelessly transmitted to the parent or a healthcare professional through a pokédex application.</p>
  
 
</div>
 
</div>

Revision as of 20:35, 19 June 2018

Biosensors utilizing ligand dependent intein-splicing: Application in a Diagnostic Pacifier

This year’s project will produce a novel, simple, portable, and point of care method for quantification of ligands present in a solution. To achieve this goal, we will be developing an engineered protein construct that utilizes ligand binding domains, intein-splicing, and a luminescent or fluorescent reporter domain. The resulting signal can then be measured and quantified, providing a dose-dependent method of measuring analytes. One application for this novel technology is to detect and quantify the amount of cortisol present in saliva. In addition to our engineered protein, we are building a complimentary pacifier with a built in luminometer detector. In practice, a child would be given the pacifier, which would allow for real time analysis of the baby’s salivary cortisol, and this information would then be wirelessly transmitted to the parent or a healthcare professional through a pokédex application.

What should this page contain?

  • A clear and concise description of your project.
  • A detailed explanation of why your team chose to work on this particular project.
  • References and sources to document your research.
  • Use illustrations and other visual resources to explain your project.

Inspiration

See how other teams have described and presented their projects:

Advice on writing your Project Description

We encourage you to put up a lot of information and content on your wiki, but we also encourage you to include summaries as much as possible. If you think of the sections in your project description as the sections in a publication, you should try to be concise, accurate, and unambiguous in your achievements.

References

iGEM teams are encouraged to record references you use during the course of your research. They should be posted somewhere on your wiki so that judges and other visitors can see how you thought about your project and what works inspired you.