Difference between revisions of "Team:HUST-China/Collaborations"

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                               <li><a class="waves-effect waves-dark" href="https://2018.igem.org/Team:HUST-China/wetlab/protocols">Protocols</a></li>
 
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                               <li><a class="waves-effect waves-dark" href="https://2018.igem.org/Team:HUST-China/Comparison between PSB">Comparison between PSB</a></li>
 
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                  <h3><strong>1. <span class="red-content">Hold the 5th iGEM Central China Regional Conference</span></strong></h3>
                      When we set up the project, we try to make the project more related to social production and life. We decided to cater to China's energy transformation strategy and provide a new idea for utilization of solar energy. We communicate the experts of this field to know more about the concerns and requirements from the society, thus guiding our project to work in a more efficient way.  
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                <p>From July 10th to 11th, 2018, the iGEM HUST-China team successfully held the 5th iGEM Central China Regional Conference. The event aimed at promoting the understanding of each team in their competition projects, improving the project content, and giving opportunities for communication and mutual learning between different teams. The teams invited to participate in the conference were the 2018 iGEM team from Huazhong Agricultural University, Taiwan University-Taiwan Jiaotong University, Wuhan University, Taiwan Zhongxing University and Huazhong University of Science and Technology. At the meeting on July 11th, each team will make a 20-minute English presentation time to introduce the project content and current progress of their competition projects, while other teams listened cand raised questions and shared their opinions. Each team presented a number of constructive issues related to project feasibility, safety, experimental protocols, modeling methods, economic costs and application prospects. During the period, delegates also had a lively and in-depth discussion on some of these issues. Many of the questions and suggestions raised in the conference have effectively pointed out the possible disappointments of the project and provided feasible solutions to these problems.</p>
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                    <h3><strong>1. <span class="red-content">A communication with our professors</span></strong></h3>
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                  <p style="font-size:14px; line-height: 25px; text-indent:0px;">In the initial project design, we hope to co-culture cyanobacteria and Shewanella to build a bio-power producing system. Cyanobacteria could utilize solar energy to produce lactate, which can be the carbon source of Shewanella. Then, Shewanella could produce electricity. However, during the discussion, Professor Yunjun Yan pointed out a serious problem. Cyanobacteria would inevitably produce oxygen during photosynthesis, and Shewanella's electrogenesis relies on an anaerobic environment. This contradiction will make the system we build unstable and cannot work efficiently and continuously. <br/>
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                   We started to search for another kind of photosynthetic bacteria. After some effort, we finally chose Rhodopseudomonas palustris. This kind of bacteria can not only carry out photosynthesis without restricting the growth of Shewanella, but use sodium acetate as a energy source for growth. Sodium acetate is a metabolite of Shewanella after using lactate. Based on all these facts, Rhodopseudomonas palustris is a really great “teammate” to work with shewanella. After we set up the project, we try to make the project more related to social production and life. We decided to cater to China's energy transformation strategy and provide a new idea for utilization of solar energy. We communicate the experts of this field to know more about the concerns and requirements from the society, thus guiding our project to work in a more efficient way.</p>
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                <h3><strong>2. <span class="red-content">Investiation on Electric Company</span></strong></h3>
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                  <h3><strong>2. <span class="red-content">Participating in CCIC </span></strong></h3>
                  <p style="font-size:14px; line-height: 20px; text-indent:0px;">We took a visit to Shenglong Electric and Hiconics Drived Technology Co. These two companies mainly focus on producing electrical energy and designing more efficient solar panels. Workers over there gave us some information about the current status and future development direction of electrical industries. They also put forward some valuable opinions on our projects in many directions, such as portability, environmental protection and marketability.</p>
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The CCiC Conference is an academic conference launched by Chinese iGEMers. Its purpose is to promote the development of synthetic biology in China. In the 5th CCiC, our team worked as an organizer in the initial preparation of CCiC. During the meeting, we invited professors major in synthetic biology to communicate with iGEMers. We listened to lectures from top scholars in synthetic biology and gained a clearer understanding of the meaning of synthetic biology and its practical applications. In addition, we also introduced our project to other iGEMers so that they could give some suggestions to us about our project. We also enhanced the friendship with each other. The common progress has fully reflected the spirit of iGEMer's synergy.  
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When we were introducing our project, students from other team asked several questions about our interview with companies. By knowing about the situation of market and social requirements, we can make our project more suitable for the status at present.</p>
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                              <h3>a. A Visit to Shenglong Electric</h3>
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                              <p tyle="font-size:14px;">Shenglong Electric is one of the leading manufacturer of power transmission and distribution equipment in China. Shenglong Electric's business covers all provinces and cities in China and more than 20 countries overseas. We visited the company on August 9, 2018 and made an interview to their technical director. He mentioned that the biggest limitation to the construction of photovoltaic power plants is natural conditions. There is no suitable large-scale land to build solar power stations in the eastern regions in China. However, the electricity consumption in this area is really high. It will be a good idea that we use bacteria, a system at a really small scale to produce enough electric energy to solve the land limitation problem. In addition, when exposed to light, Rhodopseudomonas pallidum absorbs light energy and stores it in the negative electrode chamber in form of lactate. When the light is off, even if the lactate in the negative electrode chamber is consumed, its content does not change abruptly. That means the microbial fuel cell also has a certain energy storage function, which can continuously supply power, so the problem that solar power generation cannot be continuously powered on cloudy days and nights can be solved.</p>
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                  <h3><strong>3. <span class="red-content">Manchester United iGEM Idea Exchangement</span></strong></h3>
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Our team members visited the iGEM team at the University of Manchester on August 7th and had a friendly communication, which promoted the cooperation and friendship between two universities. When communicating with the iGEM team at the University of Manchester, we found that both teams were modifying special bacterial strains, not E. coli., which raised a better understanding between the two teams. During the communication, we also discussed several issues about the competition, and had a clearer understanding of their project. This communication activity built a bridge of friendship between our two universities, which made us recognize the importance of the spirit of cooperation and learn from each other's strengths to enhance ourselves and climb the peak of science. In addition, the projects of the two teams have some steps in common, so we focused on discussing about how to make these steps better.  
                              <h3>b. A Visit to Hiconics Drived Technology Co. (Wuhan) </h3>
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                              <p tyle="font-size:14px;">On August 15, 2018, we visited Hiconics Drived Technology Co. (Wuhan). This company’s products mainly focus on equipment manufacturing and high-tech industries with high-end manufacturing of energy-saving equipment, new energy vehicles and environmental protection. Representatives from the company took us visit the new energy vehicles, solar charging sheds, charging piles and charging stations they designed. They told us many things about the development of solar energy in our country, the national policy of new energy generation and the main problems exists at present, such as the recycling and reuse of solar panels made of monocrystalline and polycrystalline silicon and the impact of secondary pollution. We still need to pay more attention to the by-product of our “Optopia” to avoid the pollution. Because we are still working at a small scale, the pollution cannot be detected. We are going to do experiments at a larger scale to see its impact on the environment if possible.</p>
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                   <h3><strong>3. <span class="red-content">Communicate with the professors</span></strong></h3>
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                   <h3><strong>4. <span class="red-content">A Communication with MIT iGEM</span></strong></h3>
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In this MIT tour, our team members got a chance to meet with iGEMers from the Massachusetts Institute of Technology and conducted communication and discussions on the 2018 competition project to provide optimization possibilities for each other. The MIT iGEM team's project this year is to solve the health problems of human tooth decay through the transformation of engineering bacteria. The team members of two schools raised many meaningful questions and suggestions on the content of each other's project, which enabled us to further improve their respective project frameworks. In addition, we have the honor to visit the biological laboratory of their team. Through this visit, we saw the difference in scientific research between ourselves and internationally renowned college students, inspiring us to constantly improve ourselves and improve our comprehensive strength and scientific research quality.
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                              <h3>a. An Interview to Professor Zhiguang Zhu from TIBI</h3>
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                              <p tyle="font-size:14px;">We are really lucky to get the opportunity to interview Professor Zhiguang Zhu, a professor who studies biomass fuel cells based on multi-enzyme catalysis. We gave Prof. Zhu a detailed introduction to the synthetic biology knowledge related to our project and asked about the feasibility of our project ideas. Prof. Zhu highly recognized our project and further discussed with the team members about the possible content of bio-batteries. After that, Professor Zhu and our team members discussed about the current international market of bio-power generation and the problems to be solved in bio-electricity industrialization, which inspired our team members about the practical application of bio-generation. He also gave some suggestions to our project. For example, we are now simply mixing the 2 kinds of bacteria together, but this may lead to a greater internal electronic resistance. Moreover, as Rhodopseudomonas palustris can transfer solar energy into lactate, we can use this part to do something else such as medical production. This interview not only gave us a further understanding of our projects, but also broadened our horizons and gave us an insight into the global status of bio-generators.</p>
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                              <h3>b. An Interview with Professor Zhou Yinhua of WNRCO </h3>
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                              <p tyle="font-size:14px;">Professor Zhou Yinhua from the National Research Center for Optoelectronics of Huazhong University of Science and Technology is mainly involved in the research of organic/polymer semiconductor energy devices. During the conversation with Professor Zhou, he gave a professional explanation to make us a understanding solar energy even further. After that, Professor Zhou explained to us in detail the advantages of solar energy projects. Our team members exchanged our ideas with Professor Zhou on the current situation of solar energy and market prospect. This conversation taught us a lot of biological knowledge that we did not learn in the past, and also pointed out new directions for our future science and technology. He pointed out several problems existed nowadays in solar energy projects, such as the obstacles between the application of solar energy projects and real life, the commercialization of solar energy, the cost and so on. Therefore, we will take these issues into consideration and try to solve them through our project.</p>
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                  <h3><strong>5. <span class="red-content">BNU-China</span></strong></h3>
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This year, team BNU-China contacted us because they were intersted in our project in 2015 which was relevant to their project this year. Therefore, they contacted our team members who was responsible for the experimental design, and asked for some details about our project. We answered their questions about designing of surface display pathway, properties of viscous protein Mcfp-3 and silica binding protein Si-tag and the characterization of their functional properties.
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                  <h3><strong>6. <span class="red-content">USTC</span></strong></h3>
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Since the USTC did a project related to Shewanella last year, we contacted the team members of this iGEM team and they provided us with the wild type of Shewanella and the shuttle plasmid of Escherichia coli- Shewanella pYYDT. In addition, they also provided us with some experience and suggestions on the cultivation and integration of Shewanella.
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                  <h3><strong>7. <span class="red-content">NCHU_Taichung</span></strong></h3>
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Besides that we contacted team NCHU_Taichung and they gave us the shuttle plasmid of Rhodopseudomonas palustris-E. coli. Furthermore, they also gave some suggestions on the cultivation and transformation of Rhodopseudomonas palustris. In addition, since team NCTU_Taichung was the first time to participate in this competition, they may be lack of experience of modeling. Thus, they wrote several emails to ask our team members about this part. We gave assistance to them on structure and direction.
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                  <h3><strong>8. <span class="red-content">Tianjin</span></strong></h3>
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In the course of project researching, our team was fortunate to read a paper from Tianjin University, which is of great help to our project. Therefore, we contacted the students of team Tianjin and contacted their instructor. The instructor answered many questions about the paper patiently and gave some advice for our project. In late August of this year, our team's student, Cheng Long , had an opportunity to communicate with their iGEM team members about their programme which was focus on Shewanella , visit their laboratory and power generation equipment. Furthermore, this year team Tianjin has designed a synthetic biology picture book for children’s enlightenment. When they told us their intention, our team found that it was a meaningful thought and could help children know more about synthetic biology which was good for their growth. Therefore, our team came up with some suggestions on stories for their picture book.
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