Tufts Team iGEM 2018!
The synthetic biology club at Tufts participates in iGEM every year. Welcome to our website :)
![](https://static.igem.org/mediawiki/2018/9/93/T--Tufts--HomePage.png)
What was our project?
We used toehold switches that collapsed upon the binding of miRNAs, causing Cas13a to be transcribed, which would theoretically allow for a signal to be detected with the use of fluorescent probes.
Why is this important?
Whenever a disease process occurs in the human body, specialized miRNAs are released. Using these to cause the collapse of our toehold could allow for early detection of disease from blood samples.
![](https://gut.bmj.com/content/gutjnl/58/11/1546/F5.large.jpg)
Who are we?
![](https://static.igem.org/mediawiki/2018/8/82/T--Tufts--Us.png)
From left to right: Mina, Anna, Kenny, and Aiden