Team:Queens Canada/Interviews
NAVIGATION
Project
Overview
Background
Laboratory
Overview
Design
Experiments
Results
Improve
Parts
Safety
Notebook
Modelling
Overview
Molecular Dynamic Simulations
Linker Development
Michaelis-Menten Kinetics
Fluid Dynamics
Hardware
Overview
Pacifier
Luminometer
Thermistor
Software
Overview
Luminometer
Linker Software
Human Practices
Overview
Expert Interviews
Market Analysis
Education & Engagement
Collaborations
InterLab
QGEM
Team
Attributions
Sponsors
Entrepreneurship
iGEM TEAM QUEENS CANADA 2018
COLLAPSE NAVIGATION
Project
Overview
Background
Laboratory
Overview
Design
Experiments
Results
Improve
Parts
Safety
Notebook
Modelling
Overview
Molecular Dynamic Simulations
Linker Development
Michaelis-Menten Kinetics
Fluid Dynamics
Hardware
Overview
Pacifier
Luminometer
Thermistor
Software
Overview
Luminometer
Linker Software
Human Practices
Overview
Expert Interviews
Market Analysis
Education & Engagement
Collaborations
InterLab
QGEM
Team
Attributions
Sponsors
Entrepreneurship
Expert Interviews
Dr. Andrea Guerin
Department of Pediatrics, Queen’s University School of Medicine
 Steering Committees and is a member of the Board of Directors for the Canadian Pediatric Society. During our interview with Dr. Dow, we were able to gain valuable knowledge about daily procedures and processes that take place in Neonatal Intensive Care Units (NICU). By evaluating current practices involved in the maintenance of neonate well-being and pain-mitigation during different procedures, we were able to better understand how our project design could be implemented and beneficial in this setting. One of the specific applications that were elaborated on during our time with Dr. Dow was the use of our technology to aid in Newborn Abstinence Syndrome treatment plans and morphine dosage determination. The other application we discussed was the possibility of aiding with the use of sucrose as an analgesic for neonates, and determining the efficacy of this pain-reducing method that is currently employed. By creating a device that can quantify cortisol, stress and pain affecting non-verbal individuals can be better understood and managed to prevent detrimental developmental effects.</p><br>
<h3>Dr. Harriet Feilotter <br>Department of Pathology and Molecular Medicine, Queen’s University</h3>
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<p>Dr. Harriet Feilotter is an Associate Professor in the Department of Pathology and Molecular Medicine at Queen’s University. Her research focuses on the development of biomarkers to be used in the screening, diagnosis and treatment of human diseases in clinical settings. Our meeting with Dr. Feilotter was very informative and provided a lot of insight into what research is required to validate our biosensor technology and demonstrate its effectiveness and clinical utility. She provided information pertaining to important parameters that must be evaluated when working with biomarkers, including analytic and clinical specificity and sensitivity values, negative and positive predictive values, the concentration range our technology can measure, the saturation point of our assay and cross-reactivity that might occur with molecules resembling cortisol. Dr. Feilotter was also very knowledgeable about the safety testing and potential experiments that may be useful in demonstrating the validity and safety of our device.</p><br>
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