Difference between revisions of "Team:Lethbridge/Design"

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<h1>Objectives</h1>
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<p class="f14">Our design was focused on making a protein nanocompartment (PNC) toolkit to better facilitate research as a whole. Our primary focus was to make the VINCEnT toolkit: </p>
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Revision as of 03:30, 16 October 2018



Design Banner Image


Objectives

Our design was focused on making a protein nanocompartment (PNC) toolkit to better facilitate research as a whole. Our primary focus was to make the VINCEnT toolkit:

References

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  • Baldwin, B., Mayer, M., Dayton, J., Pau, N., Mendila, J., Sullivan, M., Moore, A., & Mills, E. (2002) Comparative growth and feeding in zebra and quagga mussels (Dreissena Polymorpha and Dreissena bugensis): implication for North American Lakes. Canadian Journal of Aquatic Science, 59, 680-694.
  • Bartnicki, F., Bonarek, P., Kowalska, & Strzalka, W. (2017) The argi-system: one-step purification of protein tagged with arginine-rich cell-penetrating peptides. Science Reports, 7, 2619.
  • Clever, J., Sassetti, C., & Parslow, T. G. (1995) RNA secondary structure and binding sites for gag gene products in the 5' packaging signal of human immunodeficiency virus type 1. J Virol, 69, 2101-2109.
  • Glasgow, J., Capehart, S., Francis, M., & Tullman-Ercek, D. (2012) Osmolyte-mediated encapsulation of proteins inside MS2 viral capsids. ACS Nano, 6, 8658-8664.
  • Mazzone, H. (1998) CRC Handbook of Viruses: Mass-Molecular Weight Value and Related Properties. Boca Raton (FL): CRC Press LLC.
  • Molloy, D., Mayer, D., Giamberini, L., & Gaylo, M. (2013) Mode of action of Pseudomonas fluorescens strain CL145A, a lethal control agent of Dreissend mussels (Bivalvaia: Dreissenidae). Journal of Invertebrate Pathology, 113, 115-121.
  • O’Neil, A., Prevelidge, P., Basu, G., & Douglas, T. (2012) Coconfinement of fluorescent proteins: spatially enforced communication of GFP and mCherry encapsulated within the P22 capsid. Biomacromolecules, 13, 3902-3907.
  • O’Neil, A., Reichhardt, C., Johnson, B., Prevelige, P., & Douglas, T. (2011) Genetically programmed in vivo packaging of protein cargo and its controlled release from bacteriophage P22. Angewandte Chemie International Edition, 50, 7425-7428.
  • Pastuzyn, E., Da, C., Kearns, R., Kyrke-Smith, M., Taibi, A., McCormick, J., Yoder, N., Belnap, D., Erlendsson, S., Morado, D., Briggs, J., Feschotte, C., & Shepherd, D. (2018) The neuronal gene Arc encodes a repurposed retrotransposon gag protein that mediates intercellular RNA transfer. Cell. 172, 275-288.
  • Qazi, S., Miettinen, H., Wilkinson, R., McCoy, K., Douglas, T., & Wiedenheft, B. (2016) Programmed self-assembly of an active P22-Cas9 nanocarrier system. Molecular Pharmaceutics, 13, 1191-1196.
  • Schmidt, N., Mishra, A., Lai, G., & Wong, G. (2010) Arginine-rich cell-penetrating peptides. FEBS Letters, 584, 1806-1813.
  • Sprung, M., & Rose, U. (1988) Influence of food size and food quantity on the feeding of the mussel Driessena Polymorpha. Oncologia, 77, 526-532.
  • Uchida, M., LaFrance, B., Broomwell, C., Prevelige Jr., P., & Douglas, T. (2015) Higher order assembly of virus-like particles (VLPs) mediated by multi-valent protein linkers. Small, 13, 1562-1570.