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<img src="https://static.igem.org/mediawiki/2018/5/58/T--Lethbridge--banner_Software.png" width=100% alt="Software Banner Image"> | <img src="https://static.igem.org/mediawiki/2018/5/58/T--Lethbridge--banner_Software.png" width=100% alt="Software Banner Image"> | ||
<div class="content"> <!--everything added for content goes after this line CHRISISAAC--> | <div class="content"> <!--everything added for content goes after this line CHRISISAAC--> | ||
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+ | <div class="container"><div class="row"><div class="col-sm"> | ||
+ | <h2>Protein Nanocompartment Designer</h2> | ||
+ | <h5>Lethbridge iGEM 2018</h5> | ||
+ | <p>The purpose of this tool is to facilitate a match between molecular cargo and cellular target and provide a protein nanocompartment recommendation as a starting point for the design of your own VINCEnT! The tool accepts user input to specify the cellular target, molecular cargo, and approximate size of the protein nanocompartment. After submitting, a recommendation will be generated and will provide a link to a datasheet with information on the PNC.</p> | ||
+ | <p>For instance, specifying a protein cargo, to be delivered to bacteria, greater than 60nm radius should recommend the capsid of Bacteriophage P22 for this application. | ||
+ | </div></div></div> | ||
<div style="height: 25px;"></div> | <div style="height: 25px;"></div> | ||
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− | <h3> | + | <h3>Software Tool</h3> |
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− | Remember, biology is a | + | Remember, biology is a cooperative endeavour. When people aren't careful with the biology they do, it can have long lasting effects on everyone else. Accordingly, you should be very careful about encapsulating nucleic acids that are able to self-replicate or integrate into a genome. Ideally, a PNC should be used to carry single-use cargo. For instance, encapsulating a gene drive, transposable element, or other heritable element is strongly discouraged. |
</p> | </p> | ||
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Revision as of 00:28, 18 October 2018
Protein Nanocompartment Designer
Lethbridge iGEM 2018
The purpose of this tool is to facilitate a match between molecular cargo and cellular target and provide a protein nanocompartment recommendation as a starting point for the design of your own VINCEnT! The tool accepts user input to specify the cellular target, molecular cargo, and approximate size of the protein nanocompartment. After submitting, a recommendation will be generated and will provide a link to a datasheet with information on the PNC.
For instance, specifying a protein cargo, to be delivered to bacteria, greater than 60nm radius should recommend the capsid of Bacteriophage P22 for this application.