Team:Aachen/Hardware/Overview

HARDWARE

Localized Surface Plasmon Resonance Sensor

Motivation

We had three requirements:
1. Sensitvity
2. Price
3. Quick
In order to get a fast result we decided that our sensing solution needed to be cell-free, because living genetically modified organism (GMOs) in the European Union are only allowed inside S1 laboratories. The main problem with the measurement of melatonin in clinical use today is that the probes need to be sent to specialized laboratories. Here at University Hospital Aachen one of the largest hospitals in Europe, the probes for melatonin are sent 100 km away to a lab in Moenchengladbach. This is both from a time perspective but also from a cost perspective not feasible. At first the idea was to built a photometer that could detect flourescence. Though this tool could be used universally, there are many open source devices out there with good performance. The iGEM Teams Munich 2017, Aberdeen 2014, Munich 2017 In one of our discussions with one of our advisors, Prof. Dr. Wiechert,Surface Plasmon Resonance sensing is one of the most sensetive methods out there. /comparison spectrophotometers /LSPR introduction /2 parts /Results Lorem ipsum dolor sit amet, consectetuer adipiscing elit. Aenean commodo ligula eget dolor. Aenean massa. Cum sociis natoque penatibus et magnis dis parturient montes [1], nascetur ridiculus mus. Donec quam felis, ultricies nec, pellentesque eu, pretium quis, sem. Nulla consequat massa[2] quis enim. Donec pede justo, fringilla vel, aliquet nec, vulputate eget, arcu. In enim justo, rhoncus ut, imperdiet a, venenatis vitae, justo. Nullam dictum felis eu pede mollis pretium. Integer tincidunt. Cras dapibus. Vivamus elementum semper nisi. Aenean vulputate eleifend tellus. Aenean leo ligula, porttitor eu, consequat vitae, elei

billy murray1
Figure 1: Good old Bill

Lorem ipsum dolor sit amet, consectetuer adipiscing elit. Aenean commodo ligula eget dolor. Aenean massa. Cum sociis natoque penatibus et magnis dis parturient montes, nascetur ridiculus mus[3].Donec quam felis, ultricies nec, pellentesque eu, pretium quis, sem. Nulla consequat massa quis enim. Donec pede justo, fringilla vel, aliquet nec, vulputate eget, arcu In enim justo, rhoncus ut, imperdiet a, venenatis vitae, justo. Nullam dictum felis eu pede mollis pretium. Integer tincidunt. Cras dapibus. Vivamus elementum semper nisi. Aenean vulputate eleifend tellus. Aenean leo ligula, porttitor eu, consequat vitae, elei

Bill Murray

Billy Murray ist ein cooler Dude

Donec quam felis, ultricies nec, pellentesque eu, pretium quis, sem. Nulla consequat massa quis enim. Donec pede justo, fringilla vel, aliquet nec, vulputate eget, arcu. In enim justo, rhoncus ut, imperdiet a, venenatis vitae, justo. Nullam dictum felis eu pede mollis pretium. Integer tincidunt. Cras dapibus. Vivamus elementum semper nisi. Aenean vulputate eleifend tellus. Aenean leo ligula, porttitor eu, consequat vitae, elei

Billy Murray
Figure 2: Bill Murray

Donec quam felis, ultricies nec, pellentesque eu, pretium quis, sem. Nulla consequat massa quis enim. Donec pede justo, fringilla vel, aliquet nec, vulputate eget, arcu. In enim justo[4] , rhoncus ut, imperdiet a, venenatis vitae, justo. Nullam dictum felis eu pede mollis pretium. Integer tincidunt. Cras dapibus. Vivamus elementum semper nisi. Aenean vulputate eleifend tellus. Aenean leo ligula, porttitor eu, consequat vitae, elei Donec quam felis, ultricies nec, pellentesque eu,

References

  1. Hughes, J. C., Brestan, E. V., & Valle, L. A. (2004).
  2. Kelley, P. C., & Chang, P. L. (2007).
  3. Kelley, P. C., & Chang, P. L. (2007).
  4. Courtois, C. A. (2004).