Team:Toulouse-INSA-UPS/Awards
AWARDS
Gold Medal
Special Prizes
Best Basic Part
A best new part should be fully characterized, have a touch of novelty, demonstrated efficiency, and should inspire the next generation of iGEMers. We feel the Cerberus part matches this statement. It encodes a protein platform with three domains to link very different organic or inorganic molecules. We have proven its strong affinity for cellulose and the functionality of its streptavidin head, but its more impressive asset is its azidophenylalanine head, based on an unnatural amino acid which allows the grafting of any molecule with an alkyne function by click chemistry. The structure and dynamics of Cerberus were methodically modelled. We also demonstrated its efficiency to functionalize cellulose with fluorescence or magnetism, but its potential goes well beyond that since it virtually allows linking any molecule to any other, even cell polymers. We are very curious to see what the next iGEM teams will do with it!
For more details, check out our Basic Parts page!
No dogs were harmed over the course of this iGEM project.
The whole Toulouse INSA-UPS team wants to thank our sponsors, especially:
And many more. For futher information about our sponsors, please consult our Sponsors page.
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