Difference between revisions of "Team:Calgary/Chromatin Modifying Elements"
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Revision as of 09:31, 15 October 2018
CHROMATIN MODIFYING ELEMENTS
Maintenance of Integrated Genes
via minimization of gene silencing and neighbourhood effects
Gene inserts are at risk of being rendered ineffective even after successful integration into the genome, as the spread of heterochromatin and DNA methylation can cause gene silencing. Furthermore, regulatory elements within both the insert and genome near the locus of integration may interact bidirectionally, leading to changes in gene expression known as neighbourhood effects.
Maintenance of Integrated Genes
via prevention of gene silencing and minimization of neighbourhood effects
Gene therapies encounter problems even after successful gene integration. Gene inserts are at risk of being silenced
Sub Concept 1
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Sub Concept 2
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Sub Concept 3
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