Difference between revisions of "Team:Pasteur Paris/TrainingThomas3"

 
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{{Pasteur_Paris/MenuBlock}}
 
{{Pasteur_Paris/MenuBlock}}
 
<html>
 
<html>
 +
    <style type="text/css">
 +
        footer {
 +
            position:absolute;
 +
            width: 100%;
 +
            height: auto;
 +
            margin:0 auto;
 +
            margin-top:25px;
 +
            bottom:-25px;
 +
            color:white;
 +
            background:#000000;
 +
            font-family: 'Raleway', sans-serif;
 +
            z-index:10;
 +
            display:inline-block;
 +
        }
  
−
<style type="text/css">
+
        .Pasteur_footercadre {
−
#runningchip {
+
          margin:10px 15px;
−
left: 485px;
+
          float:left;
−
}
+
        }
−
#hp_small {
+
        .Pasteur_footercadre a {
−
background-color: #292929;
+
          color:white;
−
}
+
        }
−
#banner {
+
        #runningchip {
−
background-image: ;
+
            left: 5px;
−
}
+
        }
−
@media screen and (max-width: 760px) {
+
        #home_small {
−
#banner {
+
            background-color: #292929;
−
background-image: ;
+
        }
−
}
+
        #banner {
−
</style>
+
            background-image: ;
 +
        }
 +
        @media screen and (max-width: 760px) {
 +
            #banner {
 +
                background-image: ;
 +
        }
 +
    </style>
  
−
<div id="banner">
+
    <style type="text/css">
−
<h1>SAFETY</h1>
+
        #SVGcontainer1{
−
</div>
+
            position: absolute;
 +
            height: 70vh;
 +
            right: 0%;
 +
            transition: right 3s;
 +
            transition-delay: 2s;
 +
            transition-timing-function: cubic-bezier(.74,0,.34,1);
 +
            display: block;
 +
        }
 +
        #Calque_1{
 +
            height: 100%;
 +
        }
 +
        #SVGcontainer2{
 +
            position: absolute;
 +
            height: 70vh;
 +
            left: 100%;
 +
            transition: left 3s;
 +
            transition-delay: 2s;
 +
            transition-timing-function: cubic-bezier(.74,0,.34,1);
 +
            display: block;
 +
        }
 +
        #Calque_2{
 +
            height: 100%;
 +
        }
 +
        #MenuSimulator{
 +
            width: 100%;
 +
            height: 80px;
 +
            position: relative;
 +
            display: block;
 +
        }
 +
        #Path1{
 +
            display: none;
 +
            fill: black;
 +
        }
 +
        #Path2{
 +
            display: none;
 +
            fill: black;
 +
        }
 +
        #Path3{
 +
            display: none;
 +
            fill: black;
 +
        }
 +
        #Path4{
 +
            display: none;
 +
            fill: black;
 +
        }
 +
        .CirclePicto {
 +
            transition: opacity 1s;
 +
        }
 +
        .CirclePicto:hover {
 +
            fill: #000063;
 +
            cursor: pointer;
 +
        }
 +
        .ShortText {
 +
        }
 +
        /* Begin Petits Textes*/
 +
            #TEXT1{
 +
                fill: black;
 +
                opacity: .6;
 +
                display: none;
 +
            }
 +
            #TEXT1:hover{
 +
                opacity: 1;
 +
            }
 +
            #TEXT2{
 +
                fill: black;
 +
                opacity: .6;
 +
                display: none;
 +
            }
 +
            #TEXT2:hover{
 +
                opacity: 1;
 +
            }
 +
            #TEXT3{
 +
                fill: black;
 +
                opacity: .6;
 +
                display: none;
 +
            }
 +
            #TEXT3:hover{
 +
                opacity: 1;
 +
            }
 +
            #TEXT4{
 +
                fill: black;
 +
                opacity: .6;
 +
                display: none;
 +
            }
 +
            #TEXT4:hover{
 +
                opacity: 1;
 +
            }
 +
            #TEXT5{
 +
                fill: black;
 +
                opacity: .6;
 +
                display: none;
 +
            }
 +
            #TEXT5:hover{
 +
                opacity: 1;
 +
            }
 +
            #TEXT6{
 +
                fill: black;
 +
                opacity: .6;
 +
                display: none;
 +
            }
 +
            #TEXT6:hover{
 +
                opacity: 1;
 +
            }
 +
            #TEXT7{
 +
                fill: black;
 +
                opacity: .6;
 +
                display: none;
 +
            }
 +
            #TEXT7:hover{
 +
                opacity: 1;
 +
            }
 +
        /* End Petits Textes*/
 +
        @media screen and (max-width: 960px) {
 +
            #MenuSimulator{
 +
                height: 40px;
 +
            }
 +
        }
 +
        body {
 +
            margin: 0px;
 +
            padding: 0px;
 +
        }
 +
    </style>
 +
    <script type="text/javascript">
 +
        $(document).ready(function() {
 +
            $('.CirclePicto').on("click", function() {
 +
                if ($(this).prev().css("display") == "none") {
 +
                    $(this).prev().fadeIn(500);
 +
                    $(this).next().fadeIn(500);
 +
                }
 +
                else {
 +
                    $(this).prev().fadeOut(500);
 +
                    $(this).next().fadeOut(500);
 +
                }
 +
            });
 +
        });
 +
    </script>
 +
    <script type="text/javascript">
 +
        $(document).ready(function() {
 +
            $('#SVGcontainer1').css("right", "100%");
 +
            $('#SVGcontainer2').css("left", "0%");
 +
            $('#Path1').delay(4500).fadeIn(500);
 +
            $('#Path2').delay(5000).fadeIn(500);
 +
            $('#Path3').delay(5500).fadeIn(500);
 +
            $('#Path4').delay(6000).fadeIn(500);
 +
            $('#TEXT1').delay(6500).fadeIn(500);
 +
            $('#TEXT2').delay(6600).fadeIn(500);
 +
            $('#TEXT3').delay(6700).fadeIn(500);
 +
            $('#TEXT4').delay(6800).fadeIn(500);
 +
            $('#TEXT5').delay(6900).fadeIn(500);
 +
            $('#TEXT6').delay(7000).fadeIn(500);
 +
            $('#TEXT7').delay(7100).fadeIn(500);
 +
            $('#Awards').delay(7500).fadeIn(1000);
 +
            $('#US').delay(7500).fadeIn(1000);
 +
            $('#Sponsors').delay(7500).fadeIn(1000);
  
 +
        });
 +
    </script>
 +
    <body>
 +
        <div id="GeneralContent">
 +
            <div id="MenuSimulator" ></div>
 +
            <div id="SVGcontainer1">
 +
                <svg version="1.1" id="Calque_1" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" x="0px" y="0px"
 +
                    height="100%" viewBox="0 0 1920 1080" style="enable-background:new 0 0 1920 1080;" xml:space="preserve">
 +
                    <style type="text/css">
 +
                        .st0{fill:black; font-size: 40px;}
 +
                        .st1{fill:none;stroke:#000000;stroke-linecap:round;stroke-linejoin:round;}
 +
                        .st2{fill:none;stroke:#000000;stroke-miterlimit:10;}
 +
                        .st3{fill:#FFFFFF;}
 +
                        .st4{fill:none;stroke:#FFFFFF;stroke-linecap:round;stroke-linejoin:round;}
 +
                    </style>
 +
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<p><a href="#Environment" class="link">Environment</a></p>
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<p><a href="#LabSafety" class="link">Lab Safety</a></p>
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<p><a href="#References" class="link">References</a></p>
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</div>
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<div class="block title" id="Environment">
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<h1>SAFETY FOR THE ENVIRONMENT</h1>
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<div class="block full">
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                        <text id="TEXT1" transform="matrix(1 0 0 1 350 90)"><tspan x="0" y="0" class="st0"><a href="https://2018.igem.org/Team:Pasteur_Paris/Growing_Back_Nerves" style="text-decoration: none;">GROWING BACK NERVES</a></tspan></text>
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<p>A major concern of our project is to prevent any risk for the environment and the human body. The genetically modified E.coli must not leave the biofilm because they could have unintended environmental or health consequences. In order to avoid collateral damage, we implemented two barriers to prevent the genetically modified bacteria to spread outside the biofilm.</p>
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<p>The first barrier is a physical one: the biofilm is contained inside a membrane having small porous that the bacteria cannot pass through because of its size. The biocompatible membrane made of aluminum oxide and covered by a polymer have porous of 0.2 micrometers which Is smaller than the size of the bacteria composing the biofilm. The second barrier is a biological one that we integrated in the genetically modified E.coli forming the biofilm. Indeed, we worked on a kill switch that is cryosensitive. The bacteria should die when they leave the prosthesis and go in an environment that has a temperature lower than 37°C. In theory the kill switch should work when the temperature is lower than 22°C. The membrane and the kill switch confine the bacteria inside our device, so they won’t spread inside the human body or the environment.</p>
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                        <text id="TEXT2" transform="matrix(1 0 0 1 683 180)"><tspan x="0" y="0" class="st0"><a href="https://2018.igem.org/Team:Pasteur_Paris/Fighting" style="text-decoration: none;">FIGHTING INFECTIONS</a></tspan></text>
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<div class="block full">
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<img src="">
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<div class="legend">This video explains in simple terms how the kill switch works. He featured to bacteria in the biofilm that explain the objective of this biological barrier. </div>
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<div class="block title" id="LabSafety">
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<h1>LAB SAFETY: <h1><h4>A time line to understand the lab worker's daily life</h4>
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</div>
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<img src="https://static.igem.org/mediawiki/2018/7/7d/T--Pasteur_Paris--LabSafety.png">
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<div class="legend"><b>Figure 1:</b> with this interactive timeline, we want to explain the main lab safety rules which are applied every day in labs!</div>
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</div>
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                    <g class="ShortText">
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<p>This role-playing shows that, during one day as a lab worker, you may have to work in laboratories with different biosafety levels. Then, a classification exists which takes into consideration the organism used, the equipment practices and procedures you have to follow. Mainly, BSL-1 and BSL-2 are used for research. However, in some important cases, you could use BSL-3 lab and more. An important point is that rules are cumulative, it means that in BSL-2 you have to apply BSL-1 rules and BSL-2 rules.  </p>
+
                        <text id="TEXT3" transform="matrix(1 0 0 1 890 520)"><tspan x="0" y="0" class="st0"><a href="https://2018.igem.org/Team:Pasteur_Paris/Technicals" style="text-decoration: none;">NEURONARCH SYSTEM</a></tspan></text>
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</div>
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<div class="block full">
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                        <text id="TEXT4" transform="matrix(1 0 0 1 968 610)"><tspan x="0" y="0" class="st0"><a href="https://2018.igem.org/Team:Pasteur_Paris/Scenario" style="text-decoration: none;">USER SCENARIO</a></tspan></text>
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<h3 style="text-align: left; color: #e90000;">BSL-1: a basic laboratory with a biosafety level 1</h3>
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                    </g>
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<p>This laboratory is used for basic teaching and research. In this lab, you have to use good microbiological techniques (GMT). GMT rules should be applied every time you work with any microorganism, regardless the biosafety level. No safety equipment is required <b>except an open bench work</b>. No isolation of laboratory is required.</p>
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</div>
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<div class="block full">
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<h3 style="text-align: left; color: #e90000;">BSL-2: a basic laboratory with a biosafety level 2      </h3>
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<p>This laboratory is used for primary health services, diagnostic services and research. As a BSL-1 lab, you have to adopt GMT practices but also wear <b>protective clothing</b>. In this lab, you will see the biohazard sign. With a bench work, in this lab, you must have a class II BSC: biological safety cabinet, a protection against potential aerosols. No isolation of laboratory is required.</p>
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</div>
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<div class="block full">
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<h3 style="text-align: left; color: #e90000;">BSL-3: the containment laboratory with a biosafety level 3</h3>
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<p>This laboratory is used for special diagnostic services and research. You must wear special clothing. This lab is controlled for its access, and has a directional airflow. As BSL-2 lab, this lab requires a class III BSC and other primary devices for special activities. Thus, isolation of laboratory is required.</p>
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</div>
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<div class="block full">
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<h3 style="text-align: left; color: #e90000;">BSL-4: the maximum containment laboratory with a biosafety level 4</h3>
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<p>This laboratory is a dangerous pathogen unit. In this lab, you have an airlock entry, a shower exit and special waste disposal. Safety equipment is composed of a class III BSC with a double ended autoclave. Moreover, the air is always filtered. Thus, isolation of laboratory is required.<br>
+
                        <text id="TEXT5" transform="matrix(1 0 0 1 856 810)"><tspan x="0" y="0" class="st0"><a href="https://2018.igem.org/Team:Pasteur_Paris/Human_Practices" style="text-decoration: none;">HUMAN PRACTICES</a></tspan></text>
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In this lab, you must pay attention to personnel safety monitoring capability: indeed, you must have a closed-circuit television and a two-way communication for example. </p>
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</div>
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                        <text id="TEXT6" transform="matrix(1 0 0 1 790 900)"><tspan x="0" y="0" class="st0"><a href="https://2018.igem.org/Team:Pasteur_Paris/Public_Engagement" style="text-decoration: none;">EDUCATION & ENGAGEMENT</a></tspan></text>
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<div class="block separator-mark"></div>
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                    </g>
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<div class="block title" id="References">
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<h1>REFERENCES</h1>
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</div>
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                    <p style="font-size: 100%; padding: 4px">Our technology aims at promoting nerves growth towards an interface between the body and a prosthesis, in order to transmit neuronal signals.</p>
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                    <p style="font-size: 100%; padding: 4px">Besides transimitting a neuronal signal, we also want our interface to be safe and avoid potential infections.</p>
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                    <p style="font-size: 100%; padding: 4px">Discover our fully-detailed plans for our interface between the body and the prosthesis !</p>
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                    <p style="font-size: 100%; padding: 4px">To fully understand all the complex issues raised by our solution, we had to prospect and integrate human practices to our project.</p>
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                    <p style="font-size: 100%; padding: 4px">We commited ourselves to educate and inform the general public about our project and biology in general.</p>
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                    <p style="font-size: 100%; padding: 4px">We explored the prosthesis market to be sure our innovation meets the demand ; you can see here our full business plan.</p>
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                    <p style="font-size: 100%; padding: 4px">Meet all our team members !</p>
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                    <p style="font-size: 100%; padding: 4px">We want to thank all our sponsors who supported us during our adventure. Discover all of them here !</p>
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Latest revision as of 17:31, 16 October 2018

""

GROWING BACK NERVES FIGHTING INFECTIONS NEURONARCH SYSTEM USER SCENARIO HUMAN PRACTICES EDUCATION & ENGAGEMENT BUSINESS PLAN

Our technology aims at promoting nerves growth towards an interface between the body and a prosthesis, in order to transmit neuronal signals.

Besides transimitting a neuronal signal, we also want our interface to be safe and avoid potential infections.

Discover our fully-detailed plans for our interface between the body and the prosthesis !

Developping an innovation is good, but thinking of all the aspects of the user's life with our product is better.

To fully understand all the complex issues raised by our solution, we had to prospect and integrate human practices to our project.

We commited ourselves to educate and inform the general public about our project and biology in general.

We explored the prosthesis market to be sure our innovation meets the demand ; you can see here our full business plan.

All the awards we are competing for.

Meet all our team members !

We want to thank all our sponsors who supported us during our adventure. Discover all of them here !

did not go to Boston :'( but I coded this page :D