Difference between revisions of "Team:Pasteur Paris"

 
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−
{{Pasteur_Paris/Fonts}}
+
{{Pasteur_Paris/MenuBlock}}
−
{{Pasteur_Paris/Menu}}
+
−
{{Pasteur_Paris/MediaMenu}}
+
 
<html>
 
<html>
 +
    <style type="text/css">
 +
        footer {
 +
            position:absolute;
 +
            width: 100%;
 +
            height: auto;
 +
            margin:0 auto;
 +
            margin-top:25px;
 +
            bottom:-25px;
 +
            color:white;
 +
            background:#000000;
 +
            font-family: 'Raleway', sans-serif;
 +
            z-index:10;
 +
            display:inline-block;
 +
        }
  
−
<style type="text/css">  
+
        .Pasteur_footercadre {
 +
          margin:10px 15px;
 +
          float:left;
 +
        }
 +
        .Pasteur_footercadre a {
 +
          color:white;
 +
        }
 +
        #runningchip {
 +
            left: 5px;
 +
        }
 +
        #home_small {
 +
            background-color: #292929;
 +
        }
 +
        #banner {
 +
            background-image: ;
 +
        }
 +
        @media screen and (max-width: 760px) {
 +
            #banner {
 +
                background-image: ;
 +
        }
 +
    </style>
  
 +
    <style type="text/css">
 +
        #SVGcontainer1{
 +
            position: absolute;
 +
            height: 70vh;
 +
            right: 0%;
 +
            transition: right 3s;
 +
            transition-delay: 2s;
 +
            transition-timing-function: cubic-bezier(.74,0,.34,1);
 +
            display: block;
 +
        }
 +
        #Calque_1{
 +
            height: 100%;
 +
        }
 +
        #SVGcontainer2{
 +
            position: absolute;
 +
            height: 70vh;
 +
            left: 100%;
 +
            transition: left 3s;
 +
            transition-delay: 2s;
 +
            transition-timing-function: cubic-bezier(.74,0,.34,1);
 +
            display: block;
 +
        }
 +
        #Calque_2{
 +
            height: 100%;
 +
        }
 +
        #MenuSimulator{
 +
            width: 100%;
 +
            height: 80px;
 +
            position: relative;
 +
            display: block;
 +
        }
 +
        #Path1{
 +
            display: none;
 +
            fill: black;
 +
        }
 +
        #Path2{
 +
            display: none;
 +
            fill: black;
 +
        }
 +
        #Path3{
 +
            display: none;
 +
            fill: black;
 +
        }
 +
        #Path4{
 +
            display: none;
 +
            fill: black;
 +
        }
 +
        .CirclePicto {
 +
            transition: opacity 1s;
 +
        }
 +
        .CirclePicto:hover {
 +
            fill: #000063;
 +
            cursor: pointer;
 +
        }
 +
        .ShortText {
 +
        }
 +
        /* Begin Petits Textes*/
 +
            #TEXT1{
 +
                fill: black;
 +
                opacity: .6;
 +
                display: none;
 +
            }
 +
            #TEXT1:hover{
 +
                opacity: 1;
 +
            }
 +
            #TEXT2{
 +
                fill: black;
 +
                opacity: .6;
 +
                display: none;
 +
            }
 +
            #TEXT2:hover{
 +
                opacity: 1;
 +
            }
 +
            #TEXT3{
 +
                fill: black;
 +
                opacity: .6;
 +
                display: none;
 +
            }
 +
            #TEXT3:hover{
 +
                opacity: 1;
 +
            }
 +
            #TEXT4{
 +
                fill: black;
 +
                opacity: .6;
 +
                display: none;
 +
            }
 +
            #TEXT4:hover{
 +
                opacity: 1;
 +
            }
 +
            #TEXT5{
 +
                fill: black;
 +
                opacity: .6;
 +
                display: none;
 +
            }
 +
            #TEXT5:hover{
 +
                opacity: 1;
 +
            }
 +
            #TEXT6{
 +
                fill: black;
 +
                opacity: .6;
 +
                display: none;
 +
            }
 +
            #TEXT6:hover{
 +
                opacity: 1;
 +
            }
 +
            #TEXT7{
 +
                fill: black;
 +
                opacity: .6;
 +
                display: none;
 +
            }
 +
            #TEXT7:hover{
 +
                opacity: 1;
 +
            }
 +
        /* End Petits Textes*/
 +
        @media screen and (max-width: 960px) {
 +
            #MenuSimulator{
 +
                height: 40px;
 +
            }
 +
        }
 +
        body {
 +
            margin: 0px;
 +
            padding: 0px;
 +
        }
 +
    </style>
 +
    <script type="text/javascript">
 +
        $(document).ready(function() {
 +
            $('.CirclePicto').on("click", function() {
 +
                if ($(this).prev().css("display") == "none") {
 +
                    $(this).prev().fadeIn(500);
 +
                    $(this).next().fadeIn(500);
 +
                }
 +
                else {
 +
                    $(this).prev().fadeOut(500);
 +
                    $(this).next().fadeOut(500);
 +
                }
 +
            });
 +
        });
 +
    </script>
 +
    <script type="text/javascript">
 +
        $(document).ready(function() {
 +
            $('#SVGcontainer1').css("right", "100%");
 +
            $('#SVGcontainer2').css("left", "0%");
 +
            $('#Path1').delay(4500).fadeIn(500);
 +
            $('#Path2').delay(5000).fadeIn(500);
 +
            $('#Path3').delay(5500).fadeIn(500);
 +
            $('#Path4').delay(6000).fadeIn(500);
 +
            $('#TEXT1').delay(6500).fadeIn(500);
 +
            $('#TEXT2').delay(6600).fadeIn(500);
 +
            $('#TEXT3').delay(6700).fadeIn(500);
 +
            $('#TEXT4').delay(6800).fadeIn(500);
 +
            $('#TEXT5').delay(6900).fadeIn(500);
 +
            $('#TEXT6').delay(7000).fadeIn(500);
 +
            $('#TEXT7').delay(7100).fadeIn(500);
 +
            $('#Awards').delay(7500).fadeIn(1000);
 +
            $('#US').delay(7500).fadeIn(1000);
 +
            $('#Sponsors').delay(7500).fadeIn(1000);
  
−
#home_logo, #sideMenu { display:none; }
+
        });
−
#sideMenu, #top_title, .patrollink  {display:none;}
+
    </script>
−
#content { margin-left:0px; margin-top:-7px; padding:0px; width:100%;}
+
    <body>
−
body {background-color:white; }
+
        <div id="GeneralContent">
−
#bodyContent h1, #bodyContent h2, #bodyContent h3, #bodyContent h4, #bodyContent h5 { margin-bottom: 0px; }
+
            <div id="MenuSimulator" ></div>
 +
            <div id="SVGcontainer1">
 +
                <svg version="1.1" id="Calque_1" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" x="0px" y="0px"
 +
                    height="100%" viewBox="0 0 1920 1080" style="enable-background:new 0 0 1920 1080;" xml:space="preserve">
 +
                    <style type="text/css">
 +
                        .st0{fill:black; font-size: 40px;}
 +
                        .st1{fill:none;stroke:#000000;stroke-linecap:round;stroke-linejoin:round;}
 +
                        .st2{fill:none;stroke:#000000;stroke-miterlimit:10;}
 +
                        .st3{fill:#FFFFFF;}
 +
                        .st4{fill:none;stroke:#FFFFFF;stroke-linecap:round;stroke-linejoin:round;}
 +
                    </style>
 +
                    <path d="M1900,598.5c0,4.8,0,9.5,0,14.3c-53.7-1.6-107.4-3.2-161.1-4.8c-3.4-0.1-6.7-0.2-10.1-0.3c-3.4-0.1-6.7-0.1-10.1-0.1
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                    <p style="font-size: 100%; padding: 4px">Our technology aims at promoting nerves growth towards an interface between the body and a prosthesis, in order to transmit neuronal signals.</p>
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                    <p style="font-size: 100%; padding: 4px">Besides transmitting a neuronal signal, we also want our interface to be safe and avoid potential infections.</p>
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                    <p style="font-size: 100%; padding: 4px">Discover our fully-detailed plans for our interface between the body and the prosthesis!</p>
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                    <p style="font-size: 100%; padding: 4px">Developing an innovation is good, but thinking of all the aspects of the user's life with our product is better.</p>
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                    <p style="font-size: 100%; padding: 4px">To fully understand all the complex issues raised by our solution, we had to prospect and integrate human practices to our project.</p>
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                    <p style="font-size: 100%; padding: 4px">We committed ourselves to educate and inform the general public about our project and biology in general.</p>
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                    <p style="font-size: 100%; padding: 4px">We explored the prosthesis market to be sure our innovation meets the demands; you can see here our full business plan.</p>
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                    <p style="font-size: 100%; padding: 4px">Meet all our team members !</p>
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                    <p style="font-size: 100%; padding: 4px">We want to thank all our sponsors who supported us during our adventure. Discover all of them here !</p>
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                <h3><a id="US" href="https://2018.igem.org/Team:Pasteur_Paris/Team" style="text-decoration: none; color: black; display: none;">Who are we ?</a></h3>
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            <div style="right: 0%; top: 50vh; position: absolute; color: transparent;"><p>did not go to Boston:'( but I coded this page :D</p></div>
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                        <h4 style="text-align:center;"><h3 style="text-align:center;">Collaboration</h3> Contact us here: igem.pasteur@gmail.com</h4>
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                        <h1>Context: Why prosthetics and biocompatibility?</h1>
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                        <p> In today’s society where equal access to means and opportunities is a priority, disabled citizens need to be given better tools for their daily lives. In this context, prosthetics and implants will become more and more sophisticated and we think it is necessary to develop a system to enhance the interface between the implanted-human and the mechanical component thanks to synthetic biology. One of the main actor obstructing the improvement in this domain is the connection between the nerves and the controllers. In addition, the development of bacterial biofilms on prosthetics or on other implantable devices is a major health risk. Biofilms are tolerated as they can evade the immune system. However, they may become colonized by other organisms such as S. aureus or microscopic fungi. They are responsible for chronic infections with more than 200 000 people in need of re-intervention on their devices just in the USA 1 . Some of the possible remedies include improving of the interface at the nerve or prosthetics junction, and secondly preventing this interface from getting infected by other pathogenic bacteria.</p>
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                            <p><b>Figure 1 : </b></p>
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                    <h1>Our project NeuronArch</h1>
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                        <p>With NeuronArch, instead of combating the biofilm, we will develop an innovative system by subverting it. To achieve this, we will deliberately coat the implant with a genetically modified lab-grown E. coli that would serve as an interface between the synthetic prosthesis and organic tissues. </p>
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                        <p>By doing so, our innovative biofilm would be capable of promoting neural connections. Secondly, it will fight other invasive pathogenic bacteria and reduce the risk of formation of an infectious biofilm. To do so, we will test the capacity of neuronal cells to grow and redirect towards a specific target under the influence of our biofilm. Then, we will test the capacity of our biofilm to diminish an invasive bacterial population in an in vitro culture titration.</p>
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                            <p><b>Figure 3 : </b>This is us</p>
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                        <h3>References</h3>
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                        <p>1: Treatment of Infections Associated with Surgical Implants, Darouiche R. New England Journal of Medicine (2004)</p>
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Latest revision as of 13:14, 17 October 2018

""

GROWING BACK NERVES FIGHTING INFECTIONS NEURONARCH SYSTEM USER SCENARIO HUMAN PRACTICES EDUCATION & ENGAGEMENT BUSINESS PLAN

Our technology aims at promoting nerves growth towards an interface between the body and a prosthesis, in order to transmit neuronal signals.

Besides transmitting a neuronal signal, we also want our interface to be safe and avoid potential infections.

Discover our fully-detailed plans for our interface between the body and the prosthesis!

Developing an innovation is good, but thinking of all the aspects of the user's life with our product is better.

To fully understand all the complex issues raised by our solution, we had to prospect and integrate human practices to our project.

We committed ourselves to educate and inform the general public about our project and biology in general.

We explored the prosthesis market to be sure our innovation meets the demands; you can see here our full business plan.

All the awards we are competing for.

Meet all our team members !

We want to thank all our sponsors who supported us during our adventure. Discover all of them here !

did not go to Boston:'( but I coded this page :D