Difference between revisions of "Team:NEFU China/Background"

 
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<ul id="sub_02">
 
<ul id="sub_02">
 
<li><a href="https://2018.igem.org/Team:NEFU_China/Background" target="_self">BACKGROUND</a></li>
 
<li><a href="https://2018.igem.org/Team:NEFU_China/Background" target="_self">BACKGROUND</a></li>
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<li><a href="https://2018.igem.org/Team:NEFU_China/Description" target="_self">DESCRIPTION</a></li>
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<li><a href="https://2018.igem.org/Team:NEFU_China/Description" target="_self">DESCRIPTION &amp; DESIGN</a></li>
−
<li><a href="https://2018.igem.org/Team:NEFU_China/Design" target="_self">DESIGN</a></li>
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<li><a href="https://2018.igem.org/Team:NEFU_China/Coding book" target="_self">CODE BOOK</a></li>
−
<li><a href="https://2018.igem.org/Team:NEFU_China/Coding book" target="_self">CODING BOOK</a></li>
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  </ul>
 
  </ul>
 
  </li>
 
  </li>
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<li class="mainlevel" id="mainlevel_03">
 
<li class="mainlevel" id="mainlevel_03">
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  <a href="https://2018.igem.org/Team:NEFU_China/Experiment"><img id="parts" src="https://static.igem.org/mediawiki/2018/6/62/T--NEFU_China--_RESULTS.png">EXPERIMENT</a>
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  <a href="https://2018.igem.org/Team:NEFU_China/Demonstrate"><img id="parts" src="https://static.igem.org/mediawiki/2018/6/62/T--NEFU_China--_RESULTS.png">EXPERIMENTS</a>
 
  <ul id="sub_03">
 
  <ul id="sub_03">
 
  <li><a href="https://2018.igem.org/Team:NEFU_China/Lock_Key" target="_self">LOCK &amp; KEY</a></li>
 
  <li><a href="https://2018.igem.org/Team:NEFU_China/Lock_Key" target="_self">LOCK &amp; KEY</a></li>
−
  <li><a href="https://2018.igem.org/Team:NEFU_China/Suicide" target="_self">SUICIDE</a></li>
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  <li><a href="https://2018.igem.org/Team:NEFU_China/Suicide" target="_self">INFORMATION DESTRUCTION</a></li>
−
  <li><a href="https://2018.igem.org/Team:NEFU_China/Splicing" target="_self">SPLICING</a></li>
+
  <li><a href="https://2018.igem.org/Team:NEFU_China/Splicing" target="_self">Pre-RNA SPLICING</a></li>
 
  <li><a href="https://2018.igem.org/Team:NEFU_China/Demonstrate" target="_self">DEMONSTRATE</a></li>
 
  <li><a href="https://2018.igem.org/Team:NEFU_China/Demonstrate" target="_self">DEMONSTRATE</a></li>
 
  <hr>
 
  <hr>
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  <ul id="sub_05">
 
  <ul id="sub_05">
 
  <li><a href="https://2018.igem.org/Team:NEFU_China/Model" target="_self">OVERVIEW</a></li>
 
  <li><a href="https://2018.igem.org/Team:NEFU_China/Model" target="_self">OVERVIEW</a></li>
−
  <li><a href="https://2018.igem.org/Team:NEFU_China/Model1" target="_self">MODEL1</a></li>
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  <li><a href="https://2018.igem.org/Team:NEFU_China/Model1" target="_self">CORRESPONDING COEFFICIENT</a></li>
−
  <li><a href="https://2018.igem.org/Team:NEFU_China/Model2" target="_self">MODEL2</a></li>
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  <li><a href="https://2018.igem.org/Team:NEFU_China/Model2" target="_self">KILLING MODEL</a></li>
 
  </ul>
 
  </ul>
 
  </li>
 
  </li>
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  <li><a href="https://2018.igem.org/Team:NEFU_China/Attributions" target="_self">ATTRIBUTIONS</a></li>
 
  <li><a href="https://2018.igem.org/Team:NEFU_China/Attributions" target="_self">ATTRIBUTIONS</a></li>
 
  <li><a href="https://2018.igem.org/Team:NEFU_China/Members" target="_self">MEMBERS</a></li>
 
  <li><a href="https://2018.igem.org/Team:NEFU_China/Members" target="_self">MEMBERS</a></li>
−
 
−
  <li><a href="https://2018.igem.org/Team:NEFU_China/Sponsoring" target="_self">SPONSORING</a></li>
 
 
  </ul>
 
  </ul>
 
  </li>
 
  </li>
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  <a href="https://2018.igem.org/Team:NEFU_China/Human_Practices"><img id="humanpractice" src="https://static.igem.org/mediawiki/2018/9/91/T--NEFU_China--_HUMANPRACTICE.png">HUMAN PRACTICE</a>
 
  <a href="https://2018.igem.org/Team:NEFU_China/Human_Practices"><img id="humanpractice" src="https://static.igem.org/mediawiki/2018/9/91/T--NEFU_China--_HUMANPRACTICE.png">HUMAN PRACTICE</a>
 
  <ul id="sub_08">
 
  <ul id="sub_08">
 +
  <li><a href="https://2018.igem.org/Team:NEFU_China/Human_Practices" target="_self">OVERVIEW</a></li>
 
  <li><a href="https://2018.igem.org/Team:NEFU_China/Gold_integrated" target="_self">GOLD INTEGRATED</a></li>
 
  <li><a href="https://2018.igem.org/Team:NEFU_China/Gold_integrated" target="_self">GOLD INTEGRATED</a></li>
 
  <li><a href="https://2018.igem.org/Team:NEFU_China/Silver" target="_self">SILVER</a></li>
 
  <li><a href="https://2018.igem.org/Team:NEFU_China/Silver" target="_self">SILVER</a></li>
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<div id="background-content">
 
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<h1 style="height: 65px;color: orange!important;">Background</h1>
 
−
 
−
<p>
 
−
Since ancient time, people have been seeking safe ways of information storage and transfer to combat message leaks that have recently become a public security problem and great concerns all over the world. To overcome this, encryption technologies have been developed and widely used to ensure the safety of important information.
 
−
</p>
 
−
<br>
 
−
<hr>
 
−
<br>
 
−
<table id="table1">
 
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<td valign="top">
 
−
 
−
<p>
 
−
    For example, the Da Vinci Cryptograph was commonly used in the Tang Dynasty. If the messages were retrieved in a wrong way, the letter with the white phosphorus would be self-destroyed.
 
−
        </p>
 
−
</td>
 
−
<td valign="top">
 
−
<img src="https://static.igem.org/mediawiki/2018/2/2f/T--NEFU_China--Figure_2.png" alt="Figure1" id="Figure1-img">
 
−
<h2 id="Figure1-title">Figure 1: This is Figure 1.</h2>
 
−
</td>
 
−
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−
<table id="table2">
 
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<td valign="top">
 
−
<img src="https://static.igem.org/mediawiki/2018/2/2f/T--NEFU_China--Figure_2.png" alt="Figure2" id="Figure2-img">
 
−
<h2 id="Figure2-title">Figure 2: This is Figure 2.</h2>
 
−
</td>
 
−
<td valign="top">
 
−
 
−
<p>
 
−
    However, these self-destruction approaches could not provide sufficient confidentiality. Then the steganography technique was developed, by which the information could only be present after special treatments, like dipped in alum water, instead of being read directly with naked eyes.
 
−
        </p>
 
−
</td>
 
−
</table>
 
−
<table id="table3">
 
−
<td valign="top">
 
−
 
−
<p>
 
−
In 1854, the Playfair cipher invented by Charles Wheatstone made the English alphabet frequency statistical analysis useless. This method is convenient and safe to be used, which also provides a great reference to our password books.
 
−
</p>
 
−
</td>
 
−
<td valign="top">
 
−
<img src="https://static.igem.org/mediawiki/2018/2/2f/T--NEFU_China--Figure_2.png" alt="Figure3" id="Figure3-img">
 
−
<h2 id="Figure3-title">Figure 3: This is Figure 3.</h2>
 
−
</td>
 
−
</table>
 
−
<table id="table4">
 
−
<td valign="top">
 
−
 
−
<p>
 
−
    Recently, two biological encryption systems built on the spores of Bacillus subtilis have been used to safely send a key and an encrypted message, respectively. Based on the previous work, we planned to establish a DNA-based information storage and transmission system of high safety using the knowledge and techniques of synthetic biology and computer science, and this time, we used yeast to achieve our goal.
 
−
        </p>
 
−
</td>
 
−
<td valign="top">
 
−
<img src="https://static.igem.org/mediawiki/2018/2/2f/T--NEFU_China--Figure_2.png" alt="Figure4" id="Figure4-img">
 
−
<h2 id="Figure4-title">Figure 4: This is Figure 4.</h2>
 
−
</td>
 
−
</table>
 
−
<p style="color: black">
 
−
In this project, we built an information storage and transfer system with high security on using yeast spores, which consists of six modules, including “CODING”, “WRITE IN”, “LOCKING”, “MISLEADING”, “TIME DELAY SUICIDE” and “READ OUT”. Together with the computation methods developed in this project, we designed and incorporated a considerable number of genetic parts into the six modules above to ensure the safety of information stored in and transferred using our system.
 
−
</p>
 
−
<br><br><br>
 
−
</div>
 
−
 
−
<div id="background-reference">
 
−
<h1>Reference</h1>
 
−
<p> <a href="#"> [1] Pu, Jinyue and Zinkus-Boltz, Julia and Dickinson, Bryan C. (2017) Evolution of a split RNA polymerase as a versatile biosensor platform. <em><em>Nat Chem Biol 13</em></em> , 432-438 </a>
 
−
<br>
 
−
<a href="#"> [2] Pu, Jinyue and Zinkus-Boltz, Julia and Dickinson, Bryan C. (2017) Evolution of a split RNA polymerase as a versatile biosensor platform. <em><em>Nat Chem Biol 13</em></em> , 432-438 </a>
 
−
<br>
 
−
<a href="#"> [3] Pu, Jinyue and Zinkus-Boltz, Julia and Dickinson, Bryan C. (2017) Evolution of a split RNA polymerase as a versatile biosensor platform. <em><em>Nat Chem Biol 13</em></em> , 432-438 </a>
 
−
<br>
 
−
<a href="#"> [4] Pu, Jinyue and Zinkus-Boltz, Julia and Dickinson, Bryan C. (2017) Evolution of a split RNA polymerase as a versatile biosensor platform. <em><em>Nat Chem Biol 13</em></em> , 432-438 </a>
 
−
<br>
 
−
<a href="#"> [5] Pu, Jinyue and Zinkus-Boltz, Julia and Dickinson, Bryan C. (2017) Evolution of a split RNA polymerase as a versatile biosensor platform. <em><em>Nat Chem Biol 13</em></em> , 432-438 </a>
 
−
<br>
 
−
<a href="#"> [6] Pu, Jinyue and Zinkus-Boltz, Julia and Dickinson, Bryan C. (2017) Evolution of a split RNA polymerase as a versatile biosensor platform. <em><em>Nat Chem Biol 13</em></em> , 432-438 </a>s
 
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<div id="foot-title">
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<h1 style="font-size: 65px;color: orange!important;height: 84px;">Background</h1>
−
<table frame="void">
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<tr>
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<p>
−
<td>
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Since ancient time, people have been seeking for safe ways of information storage and transfer to combat message leaks that have recently become a public security problem and greatly concerns all over the world. To overcome this, encryption technologies have been developed and widely used to ensure the safety of important information.
−
<h1>Userfull links</h1>
+
</p>
−
<h2>
+
<br>
−
<a href="https://2018.igem.org/Team:NEFU_China">Home</a>
+
<hr>
−
&nbsp;&nbsp;&nbsp;&nbsp;
+
<br>
−
<a href="https://2018.igem.org/Team:NEFU_China/Model">Model</a>
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<table id="table1">
−
&nbsp;&nbsp;&nbsp;
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<td valign="top" width="60%">
−
<a href="https://2018.igem.org/Team:NEFU_China/Description">Project</a>
+
−
    &nbsp;&nbsp;
+
−
    <a href="https://2018.igem.org/Team:NEFU_China/Software">Software</a>
+
−
</h2>
+
−
+
−
<h2>
+
−
+
−
<a href="https://2018.igem.org/Team:NEFU_China/Basic_Part">Parts</a>
+
−
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
+
−
<a href="https://2018.igem.org/Team:NEFU_China/Members">Teams</a>
+
−
&nbsp;&nbsp;
+
−
<a href="https://2018.igem.org/Team:NEFU_China/Lock_Key">Results</a>
+
−
&nbsp;
+
−
<a href="https://2018.igem.org/Team:NEFU_China/Notebook">Notebook</a>
+
−
</h2>
+
−
+
−
<h2>
+
−
<a href="https://2018.igem.org/Team:NEFU_China/Human_Practices">Human &nbsp;Practice</a>
+
−
</h2>
+
−
</td>
+
−
<td style="padding-left: 70px!important;">
+
−
<h1>Follow us</h1>
+
−
<img alt="facebook" src="https://static.igem.org/mediawiki/2018/b/b5/T--NEFU_China--facebook.png">
+
−
&nbsp;&nbsp;&nbsp;
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−
        <img alt="twitter" src="https://static.igem.org/mediawiki/2018/3/36/T--NEFU_China--twitter.png">
+
−
&nbsp;&nbsp;&nbsp;
+
−
<img alt="wehchat" src="https://static.igem.org/mediawiki/2018/c/ca/T--NEFU_China--wechat.png">
+
−
        <br>
+
−
        <img alt="facebook" src="https://static.igem.org/mediawiki/2018/b/b5/T--NEFU_China--facebook.png">
+
−
&nbsp;&nbsp;&nbsp;
+
−
        <img alt="twitter" src="https://static.igem.org/mediawiki/2018/3/36/T--NEFU_China--twitter.png">
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−
&nbsp;&nbsp;&nbsp;
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−
<img alt="wehchat" src="https://static.igem.org/mediawiki/2018/c/ca/T--NEFU_China--wechat.png">
+
 
 
−
</td>
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<p>
−
<td style="padding-left: 70px!important;">
+
    For example, the <i>Da Vinci code cylinder</i> was recorded in the <i>Da Vinci </i>manuscript. If the messages were retrieved in a wrong way, the letter with the white phosphorus would be self-destroyed.
−
<h1>Contact us</h1>
+
        </p>
−
<h2>iGEM-NEFU_China2018</h2>
+
−
<h2>Email: hexinglu@nefu.edu.cn</h2>
+
</td>
−
<h3>No.26 Hexing Road, Xiangfang <br>District, Harbin, Heilongjiang <br>Province 150000</h3>
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<td valign="top" width="40%">
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</td>
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<img style="width: 330px;" src="https://static.igem.org/mediawiki/2018/4/47/T--NEFU_China--Introduction01.png" alt="Figure1" id="Figure1-img">
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</tr>
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−
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</td>
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<div id="foot-declare">
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<p>
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    <br>
−
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<table id="table2" >
−
</p>
+
<td valign="top" width="35%">
−
</div>
+
<img style="width:330px;" src="https://static.igem.org/mediawiki/2018/b/bc/T--NEFU_China--Introduction04.png" alt="Figure2" id="Figure2-img">
 +
 +
</td>
 +
<td valign="top" width="65%">
 +
 
 +
 +
<p>
 +
    However, these self-destruction approaches could not provide sufficient confidentiality. Then the steganography technique was developed, by which the information could only be present after special treatments, like dipped in alum water, instead of being read directly with naked eyes.
 +
        </p>
 +
</td>
 +
</table>
 +
<br>
 +
<table id="table3">
 +
<td valign="top" width="65%">
 +
 +
<p>
 +
In 1854, the Playfair cipher invented by Charles Wheatstone made the English alphabet frequency statistical analysis useless. This method is convenient and safe to be used, which also provides a great reference to our password books.
 +
</p>
 +
</td>
 +
<td valign="top" width="35%" style="text-align: center;
 +
">
 +
<img style="width:300px;" src="https://static.igem.org/mediawiki/2018/b/b1/T--NEFU_China--Introduction03.png" alt="Figure3" id="Figure3-img">
 +
 +
</td>
 +
</table>
 +
<br>
 +
<table id="table4">
 +
<td valign="top" width="65%">
 +
 +
<p>
 +
    Recently, two biological encryption systems built on the spores of <i>Bacillus subtilis</i> have been used to safely send a key and an encrypted message, respectively. Based on the previous work, we planned to establish a DNA-based information storage and transmission system of high safety using the knowledge and techniques of synthetic biology and computer science, and this time, we used yeast to achieve our goal.
 +
        </p>
 +
</td>
 +
<td valign="top" width="35%" style="text-align: center;
 +
">
 +
<img style="width:300px;text-align: center;" src="https://static.igem.org/mediawiki/2018/1/10/T--NEFU_China--Introduction02.png" alt="Figure4" id="Figure4-img">
 +
 +
</td>
 +
</table>
 +
<p style="color: white">
 +
In this project, we built an information storage and transfer system with high security on using yeast spores, which consists of six modules, including<span style="color:orange"> “CODING”, “WRITE IN”, “LOCKING”, “MISLEADING”, “TIME DELAY SUICIDE” and “READ OUT”</span>. Together with the computation methods developed in this project, we designed and incorporated a considerable number of genetic parts into the six modules above to ensure the safety of information stored in and transferred using our system. <br>
 +
</p>
 +
<table id="table5">
 +
<td valign="top" width="100%" style="text-align: center;
 +
">
 +
<img style="width:100%;text-align: center;" src="https://static.igem.org/mediawiki/2018/5/5b/T--NEFU_China--background-bottom.png" alt="Figure4" >
 +
 +
</td>
 +
</table>
 +
 
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Latest revision as of 21:34, 17 October 2018

Background

Background

Since ancient time, people have been seeking for safe ways of information storage and transfer to combat message leaks that have recently become a public security problem and greatly concerns all over the world. To overcome this, encryption technologies have been developed and widely used to ensure the safety of important information.



For example, the Da Vinci code cylinder was recorded in the Da Vinci manuscript. If the messages were retrieved in a wrong way, the letter with the white phosphorus would be self-destroyed.

Figure1

Figure2

However, these self-destruction approaches could not provide sufficient confidentiality. Then the steganography technique was developed, by which the information could only be present after special treatments, like dipped in alum water, instead of being read directly with naked eyes.


In 1854, the Playfair cipher invented by Charles Wheatstone made the English alphabet frequency statistical analysis useless. This method is convenient and safe to be used, which also provides a great reference to our password books.

Figure3

Recently, two biological encryption systems built on the spores of Bacillus subtilis have been used to safely send a key and an encrypted message, respectively. Based on the previous work, we planned to establish a DNA-based information storage and transmission system of high safety using the knowledge and techniques of synthetic biology and computer science, and this time, we used yeast to achieve our goal.

Figure4

In this project, we built an information storage and transfer system with high security on using yeast spores, which consists of six modules, including “CODING”, “WRITE IN”, “LOCKING”, “MISLEADING”, “TIME DELAY SUICIDE” and “READ OUT”. Together with the computation methods developed in this project, we designed and incorporated a considerable number of genetic parts into the six modules above to ensure the safety of information stored in and transferred using our system.

Figure4