Difference between revisions of "Team:Jilin China"
| Line 731: | Line 731: | ||
<div> | <div> | ||
<div class="ss5_background"> | <div class="ss5_background"> | ||
| − | <h3> | + | <a href="https://2018.igem.org/Team:Jilin_China/Background"><h3>Background</h3></a> |
</div> | </div> | ||
<div class="ss5_project"> | <div class="ss5_project"> | ||
| − | <h3>Project</h3> | + | <a href="https://2018.igem.org/Team:Jilin_China/Project/Overview"><h3>Project</h3></a> |
</div> | </div> | ||
</div> | </div> | ||
<div> | <div> | ||
<div class="ss5_result"> | <div class="ss5_result"> | ||
| − | <h3>Results</h3> | + | <a href="https://2018.igem.org/Team:Jilin_China/Result/Version_1"><h3>Results</h3></a> |
</div> | </div> | ||
<div class="ss5_engine"> | <div class="ss5_engine"> | ||
| − | <h3>Explorer</h3> | + | <a href="https://2018.igem.org/Team:Jilin_China/Part/Search_Engine"><h3>Explorer</h3></a> |
</div> | </div> | ||
</div> | </div> | ||
<div> | <div> | ||
<div class="ss5_part"> | <div class="ss5_part"> | ||
| − | <h3>Part</h3> | + | <a href="https://2018.igem.org/Team:Jilin_China/Parts"><h3>Part</h3></a> |
</div> | </div> | ||
<div class="ss5_team"> | <div class="ss5_team"> | ||
| − | <h3>Team</h3> | + | <a href="https://2018.igem.org/Team:Jilin_China/Team"><h3>Team</h3></a> |
</div> | </div> | ||
</div> | </div> | ||
Revision as of 00:30, 18 October 2018
ABSTRACT
Many strategies could be used to regulate the gene expression responding to temperature changes in bacterial cells. A well-known class of biological thermoregulatory elements includes RNA-based thermosensors (RTs), which are located in the 5'- untranslated region in mRNA. RTs could sense temperature shift and influence the mRNA stability or ribosome accessibility, thereby controlling translation efficiency.
However, natural RNA-based thermosensors have complex structure and narrow sensing temperature range, which become the biggest limitation in their application. To address this issue, we have created a synthetic RNA-based thermosensor (SynRT) toolkit with different sensing temperatures. Additionally, we built a matched search engine for users.
The SynRT toolkit version has been updated from 1.0 to 3.0, and the latest version is composed of four types of SynRTs:
Human Practices
Several Exploration Improved
OUR TOOLKITs
meanwhile Inspiring Us to Make
A DECADE
WORKFLOW
Hear Our Stories
Several Innovative Kits
Promoting Us to
SPREAD and DISCUSS
Synthetic Biology
Hear Our Stories
Model
More