Difference between revisions of "Team:Rheda Bielefeld/Human Practices"

 
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<h2> Human practices </h2>
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After we thought about our project, we wanted to know if it could be established or, more specifically, if it is an idea that is profitable.
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<br> <br>
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To know that our project would work, we contacted many experts and explained them our intention. We contacted not only allergists to check if our test strip, which would identify the pollen exposure in the air, can help to measure out the medicine, but also scientists specialized in palynology (the scientific field of pollen) and the German fruit juice industry, because our Escherichia coli would produce pectinase, a substance that is often used in the juice industry to get more juice from the fruit by cracking the cells outer wall.<br><br>
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Another part of our Human Practice was to visit the Marta Event in Herford, Germany. Here you can see more of it at the <a href="https://2018.igem.org/Team:Rheda_Bielefeld/Marta_Event" style="color:yellow;">Marta Event</a>.
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We also worked on <a href="https://2018.igem.org/Team:Rheda_Bielefeld/Biosafety" style="color:yellow;">biosafety issues</a> and <a href="https://2018.igem.org/Team:Bielefeld-CeBiTec/Public_Engagement" style="color:yellow;">biosecurity issues with the iGEM Bielefeld-CeBiTec team</a> and for our participation we recieved the Dual Use Research of Concern Button.
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<img src="https://static.igem.org/mediawiki/2018/5/5b/T--Bielefeld-CeBiTec--Dual_Use_Awareness_Button_IR.png" style="width:100%;height:auto;">
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<h1>Human Practices</h1>
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<h2> Asking allergists and professors </h2>
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At iGEM we believe societal considerations should be upfront and integrated throughout the design and execution of synthetic biology projects. “Human Practices” refers to iGEM teams’ efforts to actively consider how the world affects their work and the work affects the world. Through your Human Practices activities, your team should demonstrate how you have thought carefully and creatively about whether your project is responsible and good for the world. We invite you to explore issues relating (but not limited) to the ethics, safety, security, and sustainability of your project, and to show how this exploration feeds back into your project purpose, design and execution.
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Another part of our Human Practice was contacting some allergists to
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figure out the negative impact and side effects of antihistamines which
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are tiring but the allergy itself lowers the capability of the affected people. Therefore, we asked an allergist who works at the universiticial hospital of Aachen in the otorhinolaryngology and allergology. She told us about a study at a British school.
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The result of the study was that during the seasons, when a lot of pollen are in the air and the students take anti-allergenics, their grades differ negatively up to a whole grade<i>(Walker, S., Khan-Wasti, S., Fletscher, M., Cullinan, P., Harris,J., Sheikh, A.: “Seasonal allergic rhinitis is associated with a detrimental effect on examination performance in United Kingdom teenagers: Case control study”, in Journal of Allergy and Clinical Immunology 2007: 120,2: 381-387)</i>. So the capability of the student's performance suffers from the medicine and another side effect is fatigue.
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<p>For more information, please see the <a href="https://2018.igem.org/Human_Practices">Human Practices Hub</a>. There you will find:</p>
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Jeroen Buters, a professor at the technical university of Munich, showed real interest in our general
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project.
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Even after the Giant Jamboree, we want to stay in contact with him because he wants to continue research of our project in the future.
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<li> an <a href="https://2018.igem.org/Human_Practices/Introduction">introduction</a> to Human Practices at iGEM </li>
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<li>tips on <a href="https://2018.igem.org/Human_Practices/How_to_Succeed">how to succeed</a> including explanations of judging criteria and advice about how to conduct and document your Human Practices work</li>
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Another thing we had to think about was the negative side of developing a biosensor. If the biosensor debuts, the center for pollen in the technical university of Munich which counted the pollen before would lose their purpose and it could cause a loss of jobs because the pollen were counted by hand with a microscope.
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<li>descriptions of <a href="https://2018.igem.org/Human_Practices/Examples">exemplary work</a> to inspire you</li>
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<h2> Asking the fruit juice industry </h2>
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<li>links to helpful <a href="https://2018.igem.org/Human_Practices/Resources">resources</a></li>
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<li>And more! </li>
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We communicated with the  fruit juice industry.
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<br>
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We found out that the fruit juice industry uses pectinase for clearing
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the juice, which is an important step for clear apple juice. If our E.coli could produce the pectinase, it could be used in the fruit juice industry because the amount of pectinase the industry needs is „quantum satis“ (limitless).
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<br>
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If there is a chance for the fruit juice industry to use the E. coli, it needs to be approved for the food production by the European Union that tests the E.coli if it is detrimental to ones health and if it can be used by the industry.<br>
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So this could be another way to use our E. coli and to research in
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<p>On this page, your team should document all of your Human Practices work and activities. You should write about the Human Practices topics you considered in your project, document any activities you conducted to explore these topics (such as engaging with experts and stakeholders), describe why you took a particular approach (including referencing any work you built upon), and explain if and how you integrated takeaways from your Human Practices work back into your project purpose, design and/or execution. </p>
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the future.
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<p>If your team has gone above and beyond in work related to safety, then you should document this work on your Safety wiki page and provide a description and link on this page. If your team has developed education and public engagement efforts that go beyond a focus on your particular project, and for which would like to nominate your team for the Best Education and Public Engagement Special Prize, you should document this work on your Education and Education wiki page and provide a description and link here. </p>
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<h2>Results of Human Practice</h2>
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<p>The iGEM judges will review this page to assess whether you have met the Silver and/or Gold medal requirements based on the Integrated Human Practices criteria listed below. If you nominate your team for the <a href="https://2018.igem.org/Judging/Awards">Best Integrated Human Practices Special Prize</a> by filling out the corresponding field in the <a href="https://2018.igem.org/Judging/Judging_Form">judging form</a>, the judges will also review this page to consider your team for that prize.  
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To conclude, our Human Practice we found out that there is a general interest in our idea and that not only the medicine but also the fruit juice industry could make profit out of our project. </article>
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<h3>Silver Medal Criterion #3</h3>
 
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<p>Convince the judges you have thought carefully and creatively about whether your work is responsible and good for the world. Document how you have investigated these issues and engaged with your relevant communities, why you chose this approach, and what you have learned. Please note that surveys will not fulfill this criteria unless you follow scientifically valid methods. </p>
 
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<h3>Gold Medal Criterion #1</h3>
 
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<p>Expand on your silver medal activity by demonstrating how you have integrated the investigated issues into the purpose, design and/or execution of your project. Document how your project has changed based upon your human practices work.
 
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<h3>Best Integrated Human Practices Special Prize</h3>
 
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<p>To compete for the Best Integrated Human Practices prize, please describe your work on this page and also fill out the description on the judging form. </p>
 
  
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<p>How does your project affect society and how does society influence the direction of your project? How might ethical considerations and stakeholder input guide your project purpose and design and the experiments you conduct in the lab? How does this feedback enter into the process of your work all through the iGEM competition? Document a thoughtful and creative approach to exploring these questions and how your project evolved in the process to compete for this award!</p>
 
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<p>You must also delete the message box on the top of this page to be eligible for this prize.</p>
 
  
 
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Latest revision as of 22:44, 22 November 2018

Home
The Team Our School Bielefeld University Rheda
Description Notebook
Overview Methods Pollen PCR Assays Cloning Strategy
Human Practices Marta Event
Safety Form Biosafety
Attributions Partners

Human practices

After we thought about our project, we wanted to know if it could be established or, more specifically, if it is an idea that is profitable.

To know that our project would work, we contacted many experts and explained them our intention. We contacted not only allergists to check if our test strip, which would identify the pollen exposure in the air, can help to measure out the medicine, but also scientists specialized in palynology (the scientific field of pollen) and the German fruit juice industry, because our Escherichia coli would produce pectinase, a substance that is often used in the juice industry to get more juice from the fruit by cracking the cells outer wall.

Another part of our Human Practice was to visit the Marta Event in Herford, Germany. Here you can see more of it at the Marta Event.

We also worked on biosafety issues and biosecurity issues with the iGEM Bielefeld-CeBiTec team and for our participation we recieved the Dual Use Research of Concern Button.

Asking allergists and professors

Another part of our Human Practice was contacting some allergists to figure out the negative impact and side effects of antihistamines which are tiring but the allergy itself lowers the capability of the affected people. Therefore, we asked an allergist who works at the universiticial hospital of Aachen in the otorhinolaryngology and allergology. She told us about a study at a British school. The result of the study was that during the seasons, when a lot of pollen are in the air and the students take anti-allergenics, their grades differ negatively up to a whole grade(Walker, S., Khan-Wasti, S., Fletscher, M., Cullinan, P., Harris,J., Sheikh, A.: “Seasonal allergic rhinitis is associated with a detrimental effect on examination performance in United Kingdom teenagers: Case control study”, in Journal of Allergy and Clinical Immunology 2007: 120,2: 381-387). So the capability of the student's performance suffers from the medicine and another side effect is fatigue.
Jeroen Buters, a professor at the technical university of Munich, showed real interest in our general project. Even after the Giant Jamboree, we want to stay in contact with him because he wants to continue research of our project in the future.
Another thing we had to think about was the negative side of developing a biosensor. If the biosensor debuts, the center for pollen in the technical university of Munich which counted the pollen before would lose their purpose and it could cause a loss of jobs because the pollen were counted by hand with a microscope.

Asking the fruit juice industry

We communicated with the fruit juice industry.
We found out that the fruit juice industry uses pectinase for clearing the juice, which is an important step for clear apple juice. If our E.coli could produce the pectinase, it could be used in the fruit juice industry because the amount of pectinase the industry needs is „quantum satis“ (limitless).
If there is a chance for the fruit juice industry to use the E. coli, it needs to be approved for the food production by the European Union that tests the E.coli if it is detrimental to ones health and if it can be used by the industry.
So this could be another way to use our E. coli and to research in the future.

Results of Human Practice

To conclude, our Human Practice we found out that there is a general interest in our idea and that not only the medicine but also the fruit juice industry could make profit out of our project.