Difference between revisions of "Team:Goettingen"

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                  <a href="https://2018.igem.org/Team:Goettingen"
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                    class="sidebar-items">Home</a>
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                    <a href="https://2018.igem.org/Team:Goettingen/Notebook"
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                    <a href="https://2018.igem.org/Team:Goettingen/InterLab"
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                    <a href="https://2018.igem.org/Team:Goettingen/Model"
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                      class="sidebar-items sidebar-drop_items">Model</a>
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                    <a href="https://2018.igem.org/Team:Goettingen/Results"
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                    <a href="https://2018.igem.org/Team:Goettingen/Demonstrate"
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                      class="sidebar-items sidebar-drop_items">Demonstrate</a>
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                    <a href="https://2018.igem.org/Team:Goettingen/Improve"
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                      class="sidebar-items sidebar-drop_items">Attributions</a>
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                    <a href="https://2018.igem.org/Team:Goettingen/Parts"
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                    <a href="https://2018.igem.org/Team:Goettingen/Basic_Part"
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                      class="sidebar-items sidebar-drop_items">Basic Parts</a>
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                    <a href="https://2018.igem.org/Team:Goettingen/Part_Collection"
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                  <a href="https://2018.igem.org/Team:Goettingen/Safety"
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                    <a href="https://2018.igem.org/Team:Goettingen/Human_Practices"
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                      class="sidebar-items sidebar-drop_items">Human Practices</a>
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                    <a href="https://2018.igem.org/Team:Goettingen/Public_Engagement"
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                      class="sidebar-items sidebar-drop_items">Education & Engagement</a>
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                    <a href="https://2018.igem.org/Team:Goettingen/Applied_Design"
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                      class="sidebar-items sidebar-drop_items">Applied Design</a>
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                    <a href="https://2018.igem.org/Team:Goettingen/Entrepreneurship"
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                      class="sidebar-items sidebar-drop_items">Entrepreneurship</a>
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                    <a href="https://2018.igem.org/Team:Goettingen/Measurement"
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                      class="sidebar-items sidebar-drop_items">Measurement</a>
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                    <a href="https://2018.igem.org/Team:Goettingen/Plant"
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                      class="sidebar-items sidebar-drop_items">Plant</a>
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                    <a href="https://2018.igem.org/Team:Goettingen/Software"
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                      class="sidebar-items sidebar-drop_items">Software</a>
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                    <div class="head-line"><h2>Glyphosate on my plate?!<br/>A bacterial roundup solution to the glyphosate controversy </h2></div>
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<h1> Welcome to iGEM 2018! </h1>
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                    <p>Feeding the steadily increasing world population is a major task that relies heavily on the use of fertilizers and herbicides. Glyphosate is the prominent example for a total-herbicide. Glyphosate has been the most used herbicide in the US for the past decades, while still showing an upward trend in its usage rate. The Herbicide is a controversial substance, as its effects on human health and the environment still remains unsure, with some sources stating the suspicion for it to be carcinogenic. It also could pose a threat to biodiversity, but no real long-term studies have been carried out so far in this regard. Our team has set itself the goal to approach the glyphosate controversy through a microbial reporter system, using the well-known model organism <i>Bacillus subtilis</i>. This system should be able to detect and indicate the presence of glyphosate. During our studies we also aim to enhance the understanding of the effects of glyphosate on bacteria. We want to show how it is taken up into the bacterial cell and which pathways are affected by it. We will present our work on the development of glyphosate-resistant <i>B. subtilis</i> strains. Using these suppressor mutants, we could for the first time identify a protein that is capable of transporting glyphosate. The glyphosate-resistant strains could even provide the possibility to develop a glyphosate degradation pathway, based on the hypothesis that Bacillus might use glyphosate as its carbon source. Our human practice section is dedicated to the raise of awareness for Glyphosate and microbial research, while simultaneously cooperating with other scientific labs to achieve our goal. In the end, this should provide an updated view on the Glyphosate controversy with renewed insights into the effects of the herbicide on organisms and possibly solution approaches with Glyphosate resistances.</p>
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<p>Your team has been approved and you are ready to start the iGEM season! </p>
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                    <p style="font-weight: bold; font-size:1.1em">iGEM-Team Göttingen, Georg-August University Göttingen, Germany</p>
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                        <th>Members:</th>
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                        <td>Rica Bremenkamp, Malte Holmer, Jonas Jennrich, Veronika Lutz, Janek Meißner, Lisa Schulz, Robert Warneke, Marie Wensien, Dennis Wicke</td>
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                        <th>Supervisors:</th>
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                        <td>Prof. Jörg Stülke, Dr. Fabian Commichau</td>
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<h3>Before you start</h3>
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<p> Please read the following pages:</p>
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<li> <a href="https://2018.igem.org/Competition">Competition Hub</a> </li>
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              <div id="footer"
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<li> <a href="https://2018.igem.org/Competition/Deliverables/Wiki">Wiki Requirements page</a></li>
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<li> <a href="https://2018.igem.org/Resources/Template_Documentation">Template documentation</a></li>
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                  <span class="footer_heading">Sponsored by:</span>
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                        alt="Sartorius-Sponsor">
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                        alt="Uni-Goettingen-Sponsor">
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                        alt="GZMB-Sponsor">
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<h3> Styling your wiki </h3>
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<p>You may style this page as you like or you can simply leave the style as it is. You can easily keep the styling and edit the content of these default wiki pages with your project information and completely fulfill the requirement to document your project.</p>
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                </div>
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<p>While you may not win Best Wiki with this styling, your team is still eligible for all other awards. This default wiki meets the requirements, it improves navigability and ease of use for visitors, and you should not feel it is necessary to style beyond what has been provided.</p>  
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                  <span class="footer_heading">Contact:</span>
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                      <th>E-mail:</th>
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                      <td><a href="mailto:igem2018@gwdg.de">igem2018@gwdg.de</a></td>
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                      <th>Adress:</th>
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                      <td>c/o iGEM 2018</td>
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<h3> Uploading pictures and files </h3>
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                      <td>Department of General Microbiology</td>
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<p> You must upload any pictures and files to the iGEM 2018 server. Remember to keep all your pictures and files within your team's namespace or at least include your team's name in the file name. </p>
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<p>When you upload, set the "Destination Filename" to <b> T--YourOfficialTeamName--NameOfFile.jpg</b>. (If you don't do this, someone else might upload a different file with the same "Destination Filename", and your file would be erased!)</p>
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                      <td>Grisebachstraße </td>
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<a href="https://2018.igem.org/Special:Upload">
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UPLOAD FILES
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                      <td>37077 Göttingen</td>
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                      <td>Germany</td>
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<h3> Wiki template information </h3>
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<p>We have created these wiki template pages to help you get started and to help you think about how your team will be evaluated. You can find a list of all the pages tied to awards here at the <a href="https://2018.igem.org/Judging/Pages_for_Awards">Pages for awards</a> link. You must edit these pages to be evaluated for medals and awards, but ultimately the design, layout, style and all other elements of your team wiki is up to you!</p>
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                  <p>We are especially grateful to our numerous sponsors on <a href="https://de.gofundme.com/glyphosate-on-my-plate">gofundme,</a>&nbsp;who supported our project and made it possible.<br/> Every donor, who helped us to achieve our goals got a special place on our bacterial wall of fame and a handdrawn microbe to show our appreciation. A link to that wall can be found here:</p>
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                  <p style="text-align: center; font-size: 1.3em; padding: 10px"><a href="#">Bacterial Wall of Fame</a></p>
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<h3> Editing your wiki </h3>
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<p>On this page you can document your project, introduce your team members, document your progress and share your iGEM experience with the rest of the world! </p>  
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<p>Use WikiTools - Edit in the black menu bar to edit this page</p>
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EDIT PAGE
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<h3>Tips</h3>
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<p>This wiki will be your team’s first interaction with the rest of the world, so here are a few tips to help you get started: </p>
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<li>State your accomplishments! Tell people what you have achieved from the start. </li>
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<li>Be clear about what you are doing and how you plan to do this.</li>
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<li>You have a global audience! Consider the different backgrounds that your users come from.</li>
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<li>Make sure information is easy to find; nothing should be more than 3 clicks away.  </li>
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<li>Avoid using very small fonts and low contrast colors; information should be easy to read.  </li>
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<li>Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the <a href="https://2018.igem.org/Calendar">iGEM 2018 calendar</a> </li>
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<li>Have lots of fun! </li>
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<h3>Inspiration</h3>
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<p> You can also view other team wikis for inspiration! Here are some examples:</p>
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<li> <a href="https://2014.igem.org/Team:SDU-Denmark/"> 2014 SDU Denmark </a> </li>
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<li> <a href="https://2014.igem.org/Team:Aalto-Helsinki">2014 Aalto-Helsinki</a> </li>
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<li> <a href="https://2014.igem.org/Team:LMU-Munich">2014 LMU-Munich</a> </li>
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<li> <a href="https://2014.igem.org/Team:Michigan"> 2014 Michigan</a></li>
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<li> <a href="https://2014.igem.org/Team:ITESM-Guadalajara">2014 ITESM-Guadalajara </a></li>
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<li> <a href="https://2014.igem.org/Team:SCU-China"> 2014 SCU-China </a></li>
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Revision as of 11:58, 6 August 2018

Glyphosate on my plate?!
A bacterial roundup solution to the glyphosate controversy

Feeding the steadily increasing world population is a major task that relies heavily on the use of fertilizers and herbicides. Glyphosate is the prominent example for a total-herbicide. Glyphosate has been the most used herbicide in the US for the past decades, while still showing an upward trend in its usage rate. The Herbicide is a controversial substance, as its effects on human health and the environment still remains unsure, with some sources stating the suspicion for it to be carcinogenic. It also could pose a threat to biodiversity, but no real long-term studies have been carried out so far in this regard. Our team has set itself the goal to approach the glyphosate controversy through a microbial reporter system, using the well-known model organism Bacillus subtilis. This system should be able to detect and indicate the presence of glyphosate. During our studies we also aim to enhance the understanding of the effects of glyphosate on bacteria. We want to show how it is taken up into the bacterial cell and which pathways are affected by it. We will present our work on the development of glyphosate-resistant B. subtilis strains. Using these suppressor mutants, we could for the first time identify a protein that is capable of transporting glyphosate. The glyphosate-resistant strains could even provide the possibility to develop a glyphosate degradation pathway, based on the hypothesis that Bacillus might use glyphosate as its carbon source. Our human practice section is dedicated to the raise of awareness for Glyphosate and microbial research, while simultaneously cooperating with other scientific labs to achieve our goal. In the end, this should provide an updated view on the Glyphosate controversy with renewed insights into the effects of the herbicide on organisms and possibly solution approaches with Glyphosate resistances.

iGEM-Team Göttingen, Georg-August University Göttingen, Germany

Members: Rica Bremenkamp, Malte Holmer, Jonas Jennrich, Veronika Lutz, Janek Meißner, Lisa Schulz, Robert Warneke, Marie Wensien, Dennis Wicke
Supervisors: Prof. Jörg Stülke, Dr. Fabian Commichau