Difference between revisions of "Team:Jilin China"
Amantadine (Talk | contribs) |
|||
| Line 724: | Line 724: | ||
</section> | </section> | ||
<section class="ss4 normal model"> | <section class="ss4 normal model"> | ||
| − | <h1>Model</h1><img src="https://static.igem.org/mediawiki/2018/ | + | <h1>Model</h1><img src="https://static.igem.org/mediawiki/2018/2/29/T--Jilin_China--Home_Model.png" width="100%"></img> |
</section> | </section> | ||
<section class="ss5 normal"> | <section class="ss5 normal"> | ||
Revision as of 22:10, 17 October 2018
ABSTRACT
Many strategies could be used to regulate the gene expression responding to temperature changes in bacterial cells. A well-known class of biological thermoregulatory elements includes RNA-based thermosensors (RTs), which are located in the 5'- untranslated region in mRNA. RTs could sense temperature shift and influence the mRNA stability or ribosome accessibility, thereby controlling translation efficiency.
However, natural RNA-based thermosensors have complex structure and narrow sensing temperature range, which become the biggest limitation in their application. To address this issue, we have created a synthetic RNA-based thermosensor (SynRT) toolkit with different sensing temperatures. Additionally, we built a matched search engine for users.
The SynRT toolkit version has been updated from 1.0 to 3.0, and the latest version is composed of four types of SynRTs:
Hot-induced 5'UTR
Human Practices
Several Exploration Improved
OUR TOOLKITs
meanwhile Inspiring Us to Make
A DECADE
WORKFLOW
Hear Our Stories
Several Innovative Kits
Promoting Us to
SPREAD and DISCUSS
Synthetic Biology
Hear Our Stories
Model
More
Title