Team:NEFU China/Gold integrated
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HUMAN PRACTICECollabortion
Overview
For this part, we thoroughly considered the application of our project in the actual situation, and discussed these issues with our teachers and experts with different professional expertise in biological companies. Here are our conclusions.
Human Practices - Gold integrated
Fixation
We discussed with Professor Zeng Fansuo. When we wanted to choose a chemical agent to induce the expression of Bax (BCL2 Associated X, Apoptosis Regulator) gene, Professor Zeng suggested that we could use the α-factor to induce the pFig2c promoter to initiate the expression of Bax suicide gene. In this case, α-type yeast can naturally produce α-factor, which can be recognized by a-type yeast to induce the pFig2c promoter.
Advantages
Because we have taken into account the interception of information during message transmission, spy yeast (a-type yeast) can be induced to trigger apoptosis by the α factor of the killer yeast (α-type yeast) in the process of complete cultivation. The limited culturing time of the yeast prior to their death can prevent information from being leaked out. When designated receiver gets the information-carrying yeast and culture it properly, the yeast can successfully survive. When we discussed these questions with Professor Niu Ben, he suggested that we can use introns that can be spliced out during mRNA maturation to further encrypt our information.
Applications
Through communication with experts from the National Secrecy Bureau of Heilongjiang Province in China, we learned that if our system can be used in the encryption industry, we should be as rigorous as possible in our biological principles. We must limit the equipment and personnel access scopes to ensure that the entire encryption process is rigorous enough. For example, the transport of information-carrying yeast powder and the storage of the keys should be the responsibility of different people, and each part should be accessible to a limited number of people.
