Team:Jilin China
ABSTRACT
Manystrategies could be used by bacteria to coordinate temperature-dependent gene expression. A well-known class of biological temperature sensitive element is RNA-based thermosensor (RT), which is thermoregulatory RNA sequence in the 5'-untranslated region of mRNAs. RNA thermosensors could induce equilibrium shift between closed and open conformations of the translation initiation region under temperature variation, which influences the mRNA degradation or ribosome accessibility, thereby controlling translation efficiency.
Hot-induced 5'UTR
Human Practices
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