Team:Calgary
SNIP EQUIP FLIP
The ideal medicine is not a perfect treatment - it’s a cure.
However, major roadblocks still exist in implementation.
Advancements in genetic modification have opened avenues towards numerous tracks of scientific development. In particular, the demand for permanent health solutions has sparked massive interest in gene therapy.
Despite the potential for establishing an ideal medicine, there are still numerous challenges. The selection of an integration target site, methodology pertaining to gene delivery, and maintenance of gene expression currently limit the potential for gene therapy to become common practice.
But how do we overcome these problems?
SNIP EQUIP FLIP
University of Calgary’s Snip, Equip, Flip aims to overcome the aforementioned obstacles.
This system allows
for the creation of eukaryotic cell lines via stable integration and expression of exogenous genes.
A simple and reliable method that can be used by experienced and entrant researchers
alike that can lead to a vast array of scientific discoveries.
The expression of integrated genes is then protected and maintained over time by adding flanking chromatin modifying elements.
University of Calgary iGEM also introduced novel eukaryotic parts into the iGEM registry and successfully built a multi-cloning site.
The team has created the following to complement Snip, Equip, Flip and give back to the iGEM community:
Droplet microfluidic device designed for scalable gene transfer system.
SARA, a software tool built for iGEM participants. SARA helps iGEMers find past software projects
for use in their own projects.
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