Basic Parts
These basic parts compose the OriginALS two-dimensional ALS therapy.
We can not wait to see what other projects these parts will be part of!
For more information click on the part link:
Short description |
NickName |
Part link |
Tissue inhibitor of metalloproteinases-1 promoter (pTIMP1) |
pTIMP1 |
|
gRNA#1 for SaCas9 targeting of IKKβ under U6 promoter |
U6 g1 |
|
gRNA#2 for SaCas9 targeting of IKKβ under U6 promoter |
U6-g2 |
|
gRNA#5 for SaCas9 targeting of IKKβ under U6 promoter |
U6-g5 |
|
gRNA#6 for SaCas9 targeting of IKKβ under U6 promoter |
U6-g6 |
|
Microglia specific promoter pF4/80 |
pF4/80 |
|
Six Transmembrane Epithelial Antigen of Prostate 4 promoter (pSTEAP4) with a point mutation |
pSTEAP4 +mut |
|
Six Transmembrane Epithelial Antigen of Prostate 4 promoter (pSTEAP4) |
pSTEAP4 |
|
Synthetic minimal adenovirus major late promoter (pMLPm) |
pMLP |
|
Ribozyme flanked gRNA for SadCas9 VP64 targeting synthetic activation promoter pMLPm |
RGR gRNA |