Difference between revisions of "Team:BGU Israel"

 
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{{BGU_Israel}}
 
{{BGU_Israel}}
<!DOCTYPE html>
+
<div id="homePage">
 +
{{Template:BGU_Israel/header}}
 +
</div>
 
<html lang="en">
 
<html lang="en">
<head>
 
 
 
  <title>OriginALS</title>
 
  <meta charset="utf-8">
 
  <meta name="viewport" content="width=device-width, initial-scale=1">
 
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padding-top:10px;
 
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}
 
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width:100%;
 
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#myBtn:hover {
 
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<body id="myPage"  data-spy="scroll" data-target=".navbar" data-offset="60">
 
<body id="myPage"  data-spy="scroll" data-target=".navbar" data-offset="60">
    <div id="top"></div>
+
   <header class="img-responsive masthead text-center">
    <a id="myBtn"  href="#top" title="To Top">
+
    <span class="glyphicon glyphicon-chevron-up"></span>
+
   </a>
+
 
+
<nav id="mainMenu" class="navbar navbar-default navbar-fixed-top">
+
  <div class="container">
+
    <div class="navbar-header">
+
      <button type="button" class="navbar-toggle" data-toggle="collapse" data-target="#myNavbar">
+
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+
        <span class="icon-bar"></span>
+
        <span class="icon-bar"></span>                       
+
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+
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+
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+
    <div class="collapse navbar-collapse" id="myNavbar">
+
      <ul class="nav navbar-nav navbar-right">
+
        <li><a href="index.html">Home</a></li>
+
        <li class="dropdown">
+
        <a class="dropdown-toggle" data-toggle="dropdown" href="https://2018.igem.org/Team:BGU_Israel/Description">Project
+
        </a>
+
        <ul class="dropdown-menu pull-right">
+
          <li><a href="https://2018.igem.org/Team:BGU_Israel/Description ">Description</a></li>
+
          <li><a href="https://2018.igem.org/Team:BGU_Israel/Design">Design</a></li>
+
            <li><a href="https://2018.igem.org/Team:BGU_Israel/Results">Results</a></li>
+
          <li><a href="https://2018.igem.org/Team:BGU_ISRAEL/Protocols">Protocols</a></li>
+
            <li><a href="https://2018.igem.org/Team:BGU_ISRAEL/Notebook">Notebook</a></li>
+
           
+
        </ul>
+
      </li>
+
          <li class="dropdown">
+
        <a class="dropdown-toggle" data-toggle="dropdown" href="https://2018.igem.org/Team:BGU_Israel/Description">Team
+
        </a>
+
        <ul class="dropdown-menu pull-right">
+
          <li><a href="https://2018.igem.org/Team:BGU_Israel/Team">Members</a></li>
+
          <li><a href="https://2018.igem.org/Team:BGU_Israel/Collaborations">Collaborations</a></li>
+
        </ul>
+
      </li>
+
          <li class="dropdown">
+
        <a class="dropdown-toggle" data-toggle="dropdown" href="https://2018.igem.org/Team:BGU_Israel/Description">Parts
+
        </a>
+
        <ul class="dropdown-menu pull-right">
+
          <li><a href="https://2018.igem.org/Team:BGU_Israel/Parts">Team Parts</a></li>
+
          <li><a href="https://2018.igem.org/Team:BGU_Israel/BasicParts ">Basic Parts</a></li>
+
            <li><a href="https://2018.igem.org/Team:BGU_Israel/PartImprovement">Part Improvement</a></li>
+
          <li><a href="https://2018.igem.org/Team:BGU_Israel/PartCollection">Part Collection</a></li>
+
        </ul>
+
      </li>
+
 
+
  <li class="dropdown">
+
        <a class="dropdown-toggle" data-toggle="dropdown" href="https://2018.igem.org/Team:BGU_Israel/Description">Practices
+
 
+
        </a>
+
        <ul class="dropdown-menu pull-right">
+
          <li><a href="https://2018.igem.org/Team:BGU_ISRAEL/ALSConference">ALS Conference</a></li>
+
          <li><a href="https://2018.igem.org/Team:BGU_ISRAEL/ALSFunding">Funding Race</a></li>
+
            <li><a href="https://2018.igem.org/Team:BGU_Israel/InterLab">InterLab</a></li>
+
          <li><a href="https://2018.igem.org/Team:BGU_ISRAEL/EthicsAndSafety">Ethics and Safty</a></li>
+
        </ul>
+
      </li>
+
        <li><a href="https://2018.igem.org/Team:BGU_ISRAEL/Attributions">Attributions</a></li>
+
          <!--<li><a href="https://2018.igem.org/Team:BGU_ISRAEL/Achievments">Achievments</a></li>-->
+
      </ul>
+
    </div>
+
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+
</nav>
+
  <header class="masthead text-center">
+
 
       <div class="container my-auto">
 
       <div class="container my-auto">
 
       </div>
 
       </div>
 
     </header>
 
     </header>
  
<!-- Container (About Section) -->
+
<div id="abstract" class="bg-white text-center">
<div id="abstract" class="container-fluid text-center">
+
 
   <div class="row">
 
   <div class="row">
<div class="col-sm-8 col-sm-offset-2">
+
        <div class="col-sm-4">
     <h1>Abstract</h1>
+
</div>
      <p style="margin:0px !important; padding:0!important;" class="mb-4 justified animated fadeInRight">Recent research studies of Amyotrophic Lateral Sclerosis (ALS) suggest that brain cells that have become toxic, directly contribute to the progression of the disease. These cells change their gene expression pattern and possess distinguishing genetic markers. In addition, they drive the death of other cells in the brain among them the motor neurons. <br><br>
+
        <div class="col-sm-8">
 +
     <h1>What we are all about</h1>
 +
</div>
 +
 
 +
<div class="col-sm-4 display">
 +
        <img src="https://static.igem.org/mediawiki/2018/5/51/T--BGU_Israel--home_char.png" !important class="img-responsive">
 +
<br/>
 +
<a href="https://2018.igem.org/Team:BGU_Israel/Description" class="btn btn-info" role="button" >Learn More</a>
 +
        </div>
 +
 
 +
        <div class="col-sm-8">
 +
<p class="mb-4 justified">Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's disease, is a devastating neurodegenerative disease that affects motor neurons in the central nervous system. Recent research studies of ALS suggest that brain cells that have become toxic, directly contribute to the progression of the disease. These cells change their gene expression pattern and possess distinguishing genetic markers. In addition, they drive the death of other cells in the brain among them the motor neurons. <br><br>
 
Our objective, as the BGU-IGEM team OriginALS, is to prolong survival of ALS patients via a novel genetic engineering approach. In order to reach this objective, we combine two separate strategies as our therapeutic approach: </p>
 
Our objective, as the BGU-IGEM team OriginALS, is to prolong survival of ALS patients via a novel genetic engineering approach. In order to reach this objective, we combine two separate strategies as our therapeutic approach: </p>
               <ol class="mb-4 justified animated fadeInRight">
+
               <ol class="justified">
 
                 <li> We identify and selectively eliminate only the toxic cells. In order to identify and target the toxic-cells only, we use distinguishing markers that are unique only to them.</li>
 
                 <li> We identify and selectively eliminate only the toxic cells. In order to identify and target the toxic-cells only, we use distinguishing markers that are unique only to them.</li>
 
                 <li>We prevent the generation of new toxic cells by genetically targeting specific molecules that generate the toxic cells.</li>
 
                 <li>We prevent the generation of new toxic cells by genetically targeting specific molecules that generate the toxic cells.</li>
 
               </ol>
 
               </ol>
               <p   class="mb-4 justified animated fadeInRight">
+
               <p class="mb-4 justified">
 
In conclusion, our approach combines an apoptotic destruction of toxic cells with the prevention of the formation of new toxic cells, thus aiming to significantly reduce the occurrence of toxic cells in the central neuronal system (CNS), which is aimed at a significant deceleration of the progression rate of ALS.</p>
 
In conclusion, our approach combines an apoptotic destruction of toxic cells with the prevention of the formation of new toxic cells, thus aiming to significantly reduce the occurrence of toxic cells in the central neuronal system (CNS), which is aimed at a significant deceleration of the progression rate of ALS.</p>
 
+
        </div>
 
</div>
 
</div>
   
 
 
   </div>
 
   </div>
 +
 
</div>
 
</div>
 
<div id="video" class="container-fluid text-center">
 
<div id="video" class="container-fluid text-center">
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<div class="col-sm-8 col-sm-offset-2">
 
<div class="col-sm-8 col-sm-offset-2">
 
     <h1>Long Story Short</h1>
 
     <h1>Long Story Short</h1>
    <!---
+
 
  <video width="100%" controls>  
+
<video width="100%" height="100%" controls>
<source src="https://static.igem.org/mediawiki/2018/f/fe/IGEM_Human_Practices.mp4" type="video/mp4">  
+
  <source src="https://static.igem.org/mediawiki/2018/8/84/T--BGU_Israel--OriginALS_animation.mp4" type="video/mp4">
 
</video>
 
</video>
--->
 
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</div>
 
</div>
 
      
 
      
 
   </div>
 
   </div>
 
</div>
 
</div>
<style>
 
    .footer-list {
 
        list-style: none;
 
        color:#fff;
 
    }
 
    .footer-list-item {
 
        padding:20px 0 20px 0 !important;
 
        border-bottom: 1px solid #fff;
 
    }
 
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        border:0;
 
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        color:#000;
 
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        padding: 60px 50px;
 
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</style>
 
 
<footer class="bg-dark">
 
    <div  class="container my-auto">
 
<div class="row">
 
    <div class="col-md-4">
 
        <h3>About OrignALS</h3>
 
        <p><br>Established in 2006, EchoSense Ltd. develops innovative ultrasound Doppler systems for the diagnosis and monitoring of cardiac and pulmonary diseases. EchoSense delivers a fast,reliable and non-invasive method of diagnosis and our technology has undergone successful clinical trials in the United States, Europe and Israel. The Echosense research and development center is based in Haifa, Israel.</p>
 
        <img class="responsive-img" src="originals_white.png" width="50%">
 
       
 
        <img class="img-responsive" src="">
 
    </div>
 
    <div class="col-md-4">
 
    <ul class="footer-list">
 
        <h3>Keep in Touch</h3>
 
       
 
  <li class="footer-list-item"><img class="img-responsive social-icons" src="facebook.png" > @iGEMBGU</li>
 
  <li class="footer-list-item"><img class="img-responsive social-icons" src="instagram.png" >@igem_2018_bgu</li>
 
  <li class="footer-list-item"><img class="img-responsive social-icons" src="twitter.png" > @originalsbgu</li>
 
        <li class="footer-list-item"><img class="img-responsive social-icons" src="email.png" > bgu_israel@gmail.com</li>
 
</ul>
 
    </div>
 
    <div class="col-md-4">
 
    <ul class="footer-list">
 
        <h3>Address</h3>
 
  <li class="footer-list-item">Ben-Gurion University of the Negev<br>
 
Ben Gurion 1, Beer Sheva 8410501, Israel</li>
 
 
 
          <li class="footer-list-item"><img class="responsive-img" src="bgu_white.png"></li>
 
</ul>
 
    </div>
 
   
 
</div>
 
        </div>
 
</footer>
 
 
 
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+
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+
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+
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+
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      });
+
    } // End if
+
  });
+
 
+
  $(window).scroll(function() {
+
    $(".slideanim").each(function(){
+
      var pos = $(this).offset().top;
+
 
+
      var winTop = $(window).scrollTop();
+
        if (pos < winTop + 600) {
+
          $(this).addClass("slide");
+
        }
+
    });
+
  });
+
})
+
</script>
+
<script type="text/javascript">
+
    /*!
+
* parallax.js v1.5.0 (http://pixelcog.github.io/parallax.js/)
+
* @copyright 2016 PixelCog, Inc.
+
* @license MIT (https://github.com/pixelcog/parallax.js/blob/master/LICENSE)
+
*/
+
 
+
;(function ( $, window, document, undefined ) {
+
 
+
  // Polyfill for requestAnimationFrame
+
  // via: https://gist.github.com/paulirish/1579671
+
 
+
  (function() {
+
    var lastTime = 0;
+
    var vendors = ['ms', 'moz', 'webkit', 'o'];
+
    for(var x = 0; x < vendors.length && !window.requestAnimationFrame; ++x) {
+
      window.requestAnimationFrame = window[vendors[x]+'RequestAnimationFrame'];
+
      window.cancelAnimationFrame = window[vendors[x]+'CancelAnimationFrame'] || window[vendors[x]+'CancelRequestAnimationFrame'];
+
    }
+
 
+
    if (!window.requestAnimationFrame)
+
      window.requestAnimationFrame = function(callback) {
+
        var currTime = new Date().getTime();
+
        var timeToCall = Math.max(0, 16 - (currTime - lastTime));
+
        var id = window.setTimeout(function() { callback(currTime + timeToCall); },
+
          timeToCall);
+
        lastTime = currTime + timeToCall;
+
        return id;
+
      };
+
 
+
    if (!window.cancelAnimationFrame)
+
      window.cancelAnimationFrame = function(id) {
+
        clearTimeout(id);
+
      };
+
  }());
+
 
+
 
+
  // Parallax Constructor
+
 
+
  function Parallax(element, options) {
+
    var self = this;
+
 
+
    if (typeof options == 'object') {
+
      delete options.refresh;
+
      delete options.render;
+
      $.extend(this, options);
+
    }
+
 
+
    this.$element = $(element);
+
 
+
    if (!this.imageSrc && this.$element.is('img')) {
+
      this.imageSrc = this.$element.attr('src');
+
    }
+
 
+
    var positions = (this.position + '').toLowerCase().match(/\S+/g) || [];
+
 
+
    if (positions.length < 1) {
+
      positions.push('center');
+
    }
+
    if (positions.length == 1) {
+
      positions.push(positions[0]);
+
    }
+
 
+
    if (positions[0] == 'top' || positions[0] == 'bottom' || positions[1] == 'left' || positions[1] == 'right') {
+
      positions = [positions[1], positions[0]];
+
    }
+
 
+
    if (this.positionX !== undefined) positions[0] = this.positionX.toLowerCase();
+
    if (this.positionY !== undefined) positions[1] = this.positionY.toLowerCase();
+
 
+
    self.positionX = positions[0];
+
    self.positionY = positions[1];
+
 
+
    if (this.positionX != 'left' && this.positionX != 'right') {
+
      if (isNaN(parseInt(this.positionX))) {
+
        this.positionX = 'center';
+
      } else {
+
        this.positionX = parseInt(this.positionX);
+
      }
+
    }
+
 
+
    if (this.positionY != 'top' && this.positionY != 'bottom') {
+
      if (isNaN(parseInt(this.positionY))) {
+
        this.positionY = 'center';
+
      } else {
+
        this.positionY = parseInt(this.positionY);
+
      }
+
    }
+
 
+
    this.position =
+
      this.positionX + (isNaN(this.positionX)? '' : 'px') + ' ' +
+
      this.positionY + (isNaN(this.positionY)? '' : 'px');
+
 
+
    if (navigator.userAgent.match(/(iPod|iPhone|iPad)/)) {
+
      if (this.imageSrc && this.iosFix && !this.$element.is('img')) {
+
        this.$element.css({
+
          backgroundImage: 'url(' + this.imageSrc + ')',
+
          backgroundSize: 'cover',
+
          backgroundPosition: this.position
+
 
         });
 
         });
      }
 
      return this;
 
    }
 
 
    if (navigator.userAgent.match(/(Android)/)) {
 
      if (this.imageSrc && this.androidFix && !this.$element.is('img')) {
 
        this.$element.css({
 
          backgroundImage: 'url(' + this.imageSrc + ')',
 
          backgroundSize: 'cover',
 
          backgroundPosition: this.position
 
        });
 
      }
 
      return this;
 
    }
 
 
    this.$mirror = $('<div />').prependTo(this.mirrorContainer);
 
 
    var slider = this.$element.find('>.parallax-slider');
 
    var sliderExisted = false;
 
 
    if (slider.length == 0)
 
      this.$slider = $('<img />').prependTo(this.$mirror);
 
    else {
 
      this.$slider = slider.prependTo(this.$mirror)
 
      sliderExisted = true;
 
    }
 
 
    this.$mirror.addClass('parallax-mirror').css({
 
      visibility: 'hidden',
 
      zIndex: this.zIndex,
 
      position: 'fixed',
 
      top: 0,
 
      left: 0,
 
      overflow: 'hidden'
 
 
     });
 
     });
 
    this.$slider.addClass('parallax-slider').one('load', function() {
 
      if (!self.naturalHeight || !self.naturalWidth) {
 
        self.naturalHeight = this.naturalHeight || this.height || 1;
 
        self.naturalWidth  = this.naturalWidth  || this.width  || 1;
 
      }
 
      self.aspectRatio = self.naturalWidth / self.naturalHeight;
 
 
      Parallax.isSetup || Parallax.setup();
 
      Parallax.sliders.push(self);
 
      Parallax.isFresh = false;
 
      Parallax.requestRender();
 
    });
 
 
    if (!sliderExisted)
 
      this.$slider[0].src = this.imageSrc;
 
 
    if (this.naturalHeight && this.naturalWidth || this.$slider[0].complete || slider.length > 0) {
 
      this.$slider.trigger('load');
 
    }
 
 
  }
 
 
 
  // Parallax Instance Methods
 
 
  $.extend(Parallax.prototype, {
 
    speed:    0.2,
 
    bleed:    0,
 
    zIndex:  -100,
 
    iosFix:  true,
 
    androidFix: true,
 
    position: 'center',
 
    overScrollFix: false,
 
    mirrorContainer: 'body',
 
 
    refresh: function() {
 
      this.boxWidth        = this.$element.outerWidth();
 
      this.boxHeight      = this.$element.outerHeight() + this.bleed * 2;
 
      this.boxOffsetTop    = this.$element.offset().top - this.bleed;
 
      this.boxOffsetLeft  = this.$element.offset().left;
 
      this.boxOffsetBottom = this.boxOffsetTop + this.boxHeight;
 
 
      var winHeight = Parallax.winHeight;
 
      var docHeight = Parallax.docHeight;
 
      var maxOffset = Math.min(this.boxOffsetTop, docHeight - winHeight);
 
      var minOffset = Math.max(this.boxOffsetTop + this.boxHeight - winHeight, 0);
 
      var imageHeightMin = this.boxHeight + (maxOffset - minOffset) * (1 - this.speed) | 0;
 
      var imageOffsetMin = (this.boxOffsetTop - maxOffset) * (1 - this.speed) | 0;
 
      var margin;
 
 
      if (imageHeightMin * this.aspectRatio >= this.boxWidth) {
 
        this.imageWidth    = imageHeightMin * this.aspectRatio | 0;
 
        this.imageHeight  = imageHeightMin;
 
        this.offsetBaseTop = imageOffsetMin;
 
 
        margin = this.imageWidth - this.boxWidth;
 
 
        if (this.positionX == 'left') {
 
          this.offsetLeft = 0;
 
        } else if (this.positionX == 'right') {
 
          this.offsetLeft = - margin;
 
        } else if (!isNaN(this.positionX)) {
 
          this.offsetLeft = Math.max(this.positionX, - margin);
 
        } else {
 
          this.offsetLeft = - margin / 2 | 0;
 
        }
 
      } else {
 
        this.imageWidth    = this.boxWidth;
 
        this.imageHeight  = this.boxWidth / this.aspectRatio | 0;
 
        this.offsetLeft    = 0;
 
 
        margin = this.imageHeight - imageHeightMin;
 
 
        if (this.positionY == 'top') {
 
          this.offsetBaseTop = imageOffsetMin;
 
        } else if (this.positionY == 'bottom') {
 
          this.offsetBaseTop = imageOffsetMin - margin;
 
        } else if (!isNaN(this.positionY)) {
 
          this.offsetBaseTop = imageOffsetMin + Math.max(this.positionY, - margin);
 
        } else {
 
          this.offsetBaseTop = imageOffsetMin - margin / 2 | 0;
 
        }
 
      }
 
    },
 
 
    render: function() {
 
      var scrollTop    = Parallax.scrollTop;
 
      var scrollLeft  = Parallax.scrollLeft;
 
      var overScroll  = this.overScrollFix ? Parallax.overScroll : 0;
 
      var scrollBottom = scrollTop + Parallax.winHeight;
 
 
      if (this.boxOffsetBottom > scrollTop && this.boxOffsetTop <= scrollBottom) {
 
        this.visibility = 'visible';
 
        this.mirrorTop = this.boxOffsetTop  - scrollTop;
 
        this.mirrorLeft = this.boxOffsetLeft - scrollLeft;
 
        this.offsetTop = this.offsetBaseTop - this.mirrorTop * (1 - this.speed);
 
      } else {
 
        this.visibility = 'hidden';
 
      }
 
 
      this.$mirror.css({
 
        transform: 'translate3d('+this.mirrorLeft+'px, '+(this.mirrorTop - overScroll)+'px, 0px)',
 
        visibility: this.visibility,
 
        height: this.boxHeight,
 
        width: this.boxWidth
 
      });
 
 
      this.$slider.css({
 
        transform: 'translate3d('+this.offsetLeft+'px, '+this.offsetTop+'px, 0px)',
 
        position: 'absolute',
 
        height: this.imageHeight,
 
        width: this.imageWidth,
 
        maxWidth: 'none'
 
      });
 
    }
 
  });
 
 
 
  // Parallax Static Methods
 
 
  $.extend(Parallax, {
 
    scrollTop:    0,
 
    scrollLeft:  0,
 
    winHeight:    0,
 
    winWidth:    0,
 
    docHeight:    1 << 30,
 
    docWidth:    1 << 30,
 
    sliders:      [],
 
    isReady:      false,
 
    isFresh:      false,
 
    isBusy:      false,
 
 
    setup: function() {
 
      if (this.isReady) return;
 
 
      var self = this;
 
 
      var $doc = $(document), $win = $(window);
 
 
      var loadDimensions = function() {
 
        Parallax.winHeight = $win.height();
 
        Parallax.winWidth  = $win.width();
 
        Parallax.docHeight = $doc.height();
 
        Parallax.docWidth  = $doc.width();
 
      };
 
 
      var loadScrollPosition = function() {
 
        var winScrollTop  = $win.scrollTop();
 
        var scrollTopMax  = Parallax.docHeight - Parallax.winHeight;
 
        var scrollLeftMax = Parallax.docWidth  - Parallax.winWidth;
 
        Parallax.scrollTop  = Math.max(0, Math.min(scrollTopMax,  winScrollTop));
 
        Parallax.scrollLeft = Math.max(0, Math.min(scrollLeftMax, $win.scrollLeft()));
 
        Parallax.overScroll = Math.max(winScrollTop - scrollTopMax, Math.min(winScrollTop, 0));
 
      };
 
 
      $win.on('resize.px.parallax load.px.parallax', function() {
 
          loadDimensions();
 
          self.refresh();
 
          Parallax.isFresh = false;
 
          Parallax.requestRender();
 
        })
 
        .on('scroll.px.parallax load.px.parallax', function() {
 
          loadScrollPosition();
 
          Parallax.requestRender();
 
        });
 
 
      loadDimensions();
 
      loadScrollPosition();
 
 
      this.isReady = true;
 
 
      var lastPosition = -1;
 
 
      function frameLoop() {
 
        if (lastPosition == window.pageYOffset) {  // Avoid overcalculations
 
          window.requestAnimationFrame(frameLoop);
 
          return false;
 
        } else lastPosition = window.pageYOffset;
 
 
        self.render();
 
        window.requestAnimationFrame(frameLoop);
 
      }
 
 
      frameLoop();
 
    },
 
 
    configure: function(options) {
 
      if (typeof options == 'object') {
 
        delete options.refresh;
 
        delete options.render;
 
        $.extend(this.prototype, options);
 
      }
 
    },
 
 
    refresh: function() {
 
      $.each(this.sliders, function(){ this.refresh(); });
 
      this.isFresh = true;
 
    },
 
 
    render: function() {
 
      this.isFresh || this.refresh();
 
      $.each(this.sliders, function(){ this.render(); });
 
    },
 
 
    requestRender: function() {
 
      var self = this;
 
      self.render();
 
      self.isBusy = false;
 
    },
 
    destroy: function(el){
 
      var i,
 
          parallaxElement = $(el).data('px.parallax');
 
      parallaxElement.$mirror.remove();
 
      for(i=0; i < this.sliders.length; i+=1){
 
        if(this.sliders[i] == parallaxElement){
 
          this.sliders.splice(i, 1);
 
        }
 
      }
 
      $(el).data('px.parallax', false);
 
      if(this.sliders.length === 0){
 
        $(window).off('scroll.px.parallax resize.px.parallax load.px.parallax');
 
        this.isReady = false;
 
        Parallax.isSetup = false;
 
      }
 
    }
 
  });
 
 
 
  // Parallax Plugin Definition
 
 
  function Plugin(option) {
 
    return this.each(function () {
 
      var $this = $(this);
 
      var options = typeof option == 'object' && option;
 
 
      if (this == window || this == document || $this.is('body')) {
 
        Parallax.configure(options);
 
      }
 
      else if (!$this.data('px.parallax')) {
 
        options = $.extend({}, $this.data(), options);
 
        $this.data('px.parallax', new Parallax(this, options));
 
      }
 
      else if (typeof option == 'object')
 
      {
 
        $.extend($this.data('px.parallax'), options);
 
      }
 
      if (typeof option == 'string') {
 
        if(option == 'destroy'){
 
            Parallax.destroy(this);
 
        }else{
 
          Parallax[option]();
 
        }
 
      }
 
    });
 
  }
 
 
  var old = $.fn.parallax;
 
 
  $.fn.parallax            = Plugin;
 
  $.fn.parallax.Constructor = Parallax;
 
 
 
  // Parallax No Conflict
 
 
  $.fn.parallax.noConflict = function () {
 
    $.fn.parallax = old;
 
    return this;
 
  };
 
 
 
  // Parallax Data-API
 
 
  $( function () {
 
    $('[data-parallax="scroll"]').parallax();
 
  });
 
 
}(jQuery, window, document));
 
 
 
    </script>
 
    <script>
 
// When the user scrolls down 20px from the top of the document, show the button
 
$(window).scroll(function() {
 
    if ($(this).scrollTop() > 20) {
 
        $('#myBtn').fadeIn(400);
 
    } else {
 
        $('#myBtn').fadeOut(400);
 
    }
 
 
});
 
});
 
 
</script>
 
</script>
 
</body>
 
</body>
 
</html>
 
</html>
 +
{{Template:BGU_Israel/footer}}

Latest revision as of 17:30, 17 October 2018

OriginALS

OriginALS

What we are all about

Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's disease, is a devastating neurodegenerative disease that affects motor neurons in the central nervous system. Recent research studies of ALS suggest that brain cells that have become toxic, directly contribute to the progression of the disease. These cells change their gene expression pattern and possess distinguishing genetic markers. In addition, they drive the death of other cells in the brain among them the motor neurons.

Our objective, as the BGU-IGEM team OriginALS, is to prolong survival of ALS patients via a novel genetic engineering approach. In order to reach this objective, we combine two separate strategies as our therapeutic approach:

  1. We identify and selectively eliminate only the toxic cells. In order to identify and target the toxic-cells only, we use distinguishing markers that are unique only to them.
  2. We prevent the generation of new toxic cells by genetically targeting specific molecules that generate the toxic cells.

In conclusion, our approach combines an apoptotic destruction of toxic cells with the prevention of the formation of new toxic cells, thus aiming to significantly reduce the occurrence of toxic cells in the central neuronal system (CNS), which is aimed at a significant deceleration of the progression rate of ALS.

Long Story Short

OriginALS

About Us


The BGU-iGEM team “OriginALS” hopes to develop an innovative therapeutic approach to prolong the life expectancy of ALS patients, using Synthetic Biology. We are dedicated to promoting ALS awareness and research in Israel through public engagement and educational activities.